Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
Reaction mass of Potassium sodium 3-{[4-({3-(substitutedamino)-4-[(2-sulfonato-4-{[2-(sulfonatooxy)ethyl]sulfonyl}phenyl)diazenyl]phenyl}amino)-6-chloro-heteromonocyl-2-yl]amino}-2-substituted-5-{[2-(sulfonatooxy)ethyl]sulfonyl}benzenesulfonate (1:3:1) and Potassium sodium 3-[(4-{[3-(subsitutedamino)-4-{[4-(ethenylsulfonyl)-2-sulfonatophenyl]diazenyl}phenyl]amino}-6-chloro-heteromonocy-2-yl)amino]-2-substituted-5-{[2-(sulfonatooxy)ethyl]sulfonyl}benzenesulfonate (3:9:3)
EC number: - | CAS number: -
Partition coefficient
Administrative data
Link to relevant study record(s)
Description of key information
Determination of the partition coefficient of FAT 40863/A TE using the shake-flask method.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- -2.79
- at the temperature of:
- 21.9 °C
Additional information
The determination was carried out using the shake-flask method, designed to be compatible with Method A8 Partition Coefficient of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 107 of the OECD Guidelines for Testing of Chemicals, 27 July 1995.
Since the test item is a salt, testing was performed at pH 7 as indicated in test guidance.
The test system consisted of an aqueous and an n-octanol phase in the same vessel. A defined amount of test item was added (pre-dissolved in the appropriate phase). Partition of the test item between both phases was achieved by inversion of the mixture. The temperature was in the range of 20 to 25 °C and kept constant (± 1 °C).
Discussion
The determination of partition coefficient was performed using the shake-flask method, as indicated for salts.
The stock solution was prepared in n-octanol saturated water in place of water saturated n-octanol. This was due to the insolubility of the test item in the organic phase. This issue has been considered to have had a negligible impact on the overall results and has been considered to be more appropriate to obtain a realistic partition coefficient value.
Conclusion
The partition coefficient of the test item has been determined to be 1.67 x 10-3at 21.9 ± 0.5 °C, log10Pow-2.79.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
