Registration Dossier
Registration Dossier
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EC number: 419-330-5 | CAS number: -
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
FAT 40543/A was shown to have no toxic effects to zebra-fish, even well above the limit of water solubility. Thus, the NOEC is 92.9 mg/L (maximum concentration measured in test) respectively 0.38 mg/L based on maximum water solubility in distilled water and the LC50 is accordingly > 92.9 mg/L respectively >0.38 mg/L.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 92.9 mg/L
Additional information
The nominal concentrations for the main test were selected as 45, 100 and 220 mg test article/L. Additionally, a vehicle and a blank control without any additions were tested. The test concentrations were prepared from direct samples weight. Since the test substance is badly soluble in water, all test concentrations were clouded and a sediment at the bottom of the test aquaria was observed after the start. Because of the low solubility of the test article in the test water, the actual test concentrations in the analysed test media were in the range of 26.2 - 77.8 % of the nominal values. Therefore, the reported results are related to the actual mean concentrations of the test article in the test medium measured at the beginning, at 48 hours and at the end of the test. The test medium was strongly coloured in all test concentrations. Therefore, the behaviour of the fish could not be observed.
In the controls and in all test concentrations no mortality of the test fish was observed after 96 hours. The NOEC and the LCQ value after 96 hours were determined to be 92.9 mg/l. The LC100 value could not be determined , but is clearly higher than 92.9 mg/l.
The LC50 value after 96 hours could not be calculated.
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