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EC number: 200-753-7
CAS number: 71-43-2
(Draize et al 1944):
Time after end of application
Mean score for erythema
Mean score for edema
The irritation potential of benzene was
assessed on the skins of six shaved rabbits exposed to neat benzene for
4 hours, using an exposure chamber of 6 cm2. One hour after
exposure oedema grade 2 and erythema grade 1 were documented. No oedema,
but mean scores of 2.0/2.2/2.4 for erythema were recorded at 24, 48, and
72 hours after the end of exposure. Erythema increased to a mean of
grade 3 at 6 days.
It is concluded that benzene is irritating
to rabbit skin and should be classified as Category 2, H315 under CLP.
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