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EC number: 239-937-7
CAS number: 15834-04-5
No chronic toxic effects to fish up to the limit of water solubility (< 1 mg/L) is expected, however a further long term toxicity test to aquatic invertebrates for CAS 15834-04-5 is planned.
The chemical safety assessment according to Annex I of Regulation (EC)
No. 1907/2006 does not indicate the need to investigate further the
long-term toxicity to fish. Thus, in accordance to Annex IX, column 2 no
further long-term toxicity testing to fish is proposed.
The available experimental studies on aquatic toxicity for all members
of the polyol esters category and in particular those which were chosen
as suitable read across for
(CAS-No.15834-04-5) show that on all three trophic levels no acute toxic
effects up to the water solubility occur. Furthermore the available data
on the long term toxicity of aquatic invertebrates does not reveal
adverse effects to daphnids. An experimental study for long-term
toxicity to aquatic invertebrates for 2,2-bis[[(1-oxopentyl)
oxy]methyl]propane-1,3-diyl divalerate (CAS-No. 15834-04-5) is planned.
This study together with a 21 day-long-term study with Daphnia magna
(Letinski and Bragin, 2012) for decanoic acid, mixed esters with
heptanoic acid, octanoic acid, pentaerythritol and valeric acid (CAS
71010-76-9) and a 15 day-long-term study with Daphnia magna (Low, 1996)
for fatty acids, C8-10 (even numbered), di-and triesters with
propylidynetrimethanol (CAS.No. 11138-60-6) will provide sufficient
evidence for the chronic ecotoxicity of this substance.
Moreover, as there was no sign that fish are the most sensitive species
in the short term tests, one can expected that a long-term test with
fish will not generate different results than the existing long-term
test with Daphnia. Hence due to animal welfare reasons and to avoid
unnecessary vertebrate tests, no further long-term test with fish is
required for 2,2-bis[[(1-oxopentyl)oxy]methyl]propane-1,3-diyl
divalerate (CAS-No.15834-04-5). In addition, due to its ready
biodegradability it is not likely that aquatic organisms are exposed to
the test substance since it will be ultimately degraded in sewage
treatment plants. Therefore, it can be concluded that chronic exposure
of this substance to fish is unlikely and that it would not pose a
higher risk to fish than it does to daphnids.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Tällä verkkosivustolla käytetään evästeitä parhaan mahdollisen käyttäjäkokemuksen varmistamiseksi.
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