Registration Dossier
Registration Dossier
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EC number: 261-716-9 | CAS number: 59354-78-8
Endpoint summary
Administrative data
Description of key information
Additional information
The following Aquatic toxicity PNECs were derived for Neononanoic acid based on the available study data:
The O.E.C.D. 203, GLP. Klimisch 1 rainbow trout study is condisered the most reliable and appropriate dataset for deriving a Fish PNEC value. The NOEC value from this study was 460 mg/L. Following ECHA guidance (RIP 3.2, Chapter R. 10) the derived Fresh water fish PNEC is 460 ug/L and the Marine fish PNEC is 46 ug/L.
An O.E.C.D. 202 Testing Guideline GLP Klimisch 1 study was conducted with the fresh water crustacea Daphnia magna with analytical verification of test substance concentration. The NOEC for the Daphnia magna study was 220 mg/L. Based on ECHA guidance (RIP 3.2, Chapter R. 10) the PNEC for fresh water crustacea is 220 ug/L and the PNEC for marine crustacea is 22 ug/L.
The Klimisch 1 acute 72 hr algal study conducted according to O.E.C.D. Testing Guideline 201 with GLP compliance and test substance concetration analytical determination is the most appropriate and reliable study on which to base an algal PNEC. The NOEC value for this study was 100 mg/L. Following ECHA guidance (RIP 3.2, Chapter R. 10) the Fresh water algae PNEC is 100 ug/L and the marine algae PNEC is10 ug/L.
Based on the derived PNECs for the three tropic levels, the PNEC of 100 ug/l is believed to be protective of fresh water organisms and the PNEC of 10 ug/L is considerd to be protective of marine organisms.
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