Registration Dossier
Registration Dossier
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EC number: 204-909-5 | CAS number: 128-80-3
Endpoint summary
Administrative data
Description of key information
Bioaccumulation: aquatic / sediment
The bioaccumulation study in fishwas conducted for estimating the BCF (bioaccumulation factor) value of test chemical (authoritative database, 2017). The bioaccumulation factor (BCF) value was calculated using a log Kow of 8.69 and a regression-derived equation. The estimated BCF (bioaccumulation factor) value of test chemical was determined to be 500 dimensionless, which does not exceed the bioconcentration threshold of 2000, indicating that the test chemical is considered to be non-accumulative in aquatic organisms.
Additional information
Bioaccumulation: aquatic / sediment
Various studies and predicted data of the test chemical were reviewed for the bioaccumulation end point which are summarized as below:
In a key study from authoritative databases (2017), the bioaccumulation study in fishwas conducted for estimating the BCF (bioaccumulation factor) value of test chemical. The bioaccumulation factor (BCF) value was calculated using a log Kow of 8.69 and a regression-derived equation. The estimated BCF (bioaccumulation factor) value of test chemical was determined to be 500 dimensionless.
In a supporting study, the bioaccumulation study in fish was conducted for estimating the BCF (bioaccumulation factor) value of test chemical (secondary source, 2005). The estimated BCF (bioaccumulation factor) value of test chemical was determined to be 45.70 dimensionless.
For the test chemical, bioaccumulation study in fish was conducted for estimating the BCF (bioaccumulation factor) value of test chemical (secondary source, 1987). The bioaccumulation factor (BCF) value was calculated using a log Kow of 6.657 and a regression-derived equation. The estimated BCF (bioaccumulation factor) value of test chemical was determined to be ≥ 1000 dimensionless.
In a prediction done using the BCFBAF Program of Estimation Programs Interface was used to predict the bioconcentration factor (BCF) of test chemical. The bioconcentration factor (BCF) of test chemical was estimated to be 516.4 L/kg whole body w.w (at 25 deg C).
On the basis of above results for test chemical (from authoritative databases, secondary source and modelling database,2018), it can be concluded that the BCF value of test chemical ranges from 45.70 to ≥ 1000, respectively,which does not exceed the bioconcentration threshold of 2000, indicating that the test chemical is not expected to bioaccumulate in the food chain.
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