Registration Dossier
Registration Dossier
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EC number: 213-986-4 | CAS number: 1071-22-3
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
A 48-hour EC50 value of >100 mg/L and NOEC of ≥100 mg/L have been determined for the effects of the read-across substance 3-(triethoxysilyl)propiononitrile on mobility of Daphnia magna. It is likely that the test organisms were exposed to both the test substance and its hydrolysis products.
Key value for chemical safety assessment
Additional information
No data are available for the submission substance,
3-(trichlorosilyl)propiononitrile.
However data are available for the read-across substance3-(triethoxysilyl)propiononitrile.
The hydrolysis half-lives of 3 -(trichlorosilyl)propiononitrile and 3-(triethoxysilyl)propiononitrileindicate that, under conditions relevant to ecotoxicity assessment, both will hydrolyse to3-(trihydroxysilyl)propionitrile. The other hydrolysis products are hydrogen chloride and ethanol, respectively; the properties of these substances are well characterised. Ethanol is non-toxic to the environment and it is considered unlikely that it’s presence significantly affected the results of the test performed with3-(triethoxysilyl)propiononitrile.Effects of hydrogen chloride on aquatic organisms are limited to those that result from changes to pH in unbuffered media.Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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