Brief Profile

Data platform availability banner - brief profile

Please be aware that the REACH registration parts of this Brief Profile are no longer maintained; they remain frozen as of 19th May 2023. All other data parts (substance identity, C&L, key regulatory lists etc. are up to date).

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

EC / List no.:
216-374-5
CAS no.:
1569-02-4
Index number:
603-177-00-8
Molecular formula:
C5H12O2
SMILES:
CCOCC(C)O
InChI:
InChI=1/C5H12O2/c1-3-7-4-5(2)6/h5-6H,3-4H2,1-2H3
Type of substance:
Mono constituent substance
Origin:
Organic
Registered compositions:
8
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Warning! According to the harmonised classification and labelling (CLP00) approved by the European Union, this substance is a flammable liquid and vapour and may cause drowsiness or dizziness.

Additionally, the classification provided by companies to ECHA in REACH registrations identifies that this substance causes serious eye irritation.

Breakdown of all 679 C&L notifications submitted to ECHA

Flam. Liq. 3 H226 Harmonised Classification
STOT SE 3 H336 Harmonised Classification
Eye Irrit. 2 H319
STOT SE 3 H335
Eye Irrit. 2B H320
Not Classified
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://echa.europa.eu/o/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://echa.europa.eu/o/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://echa.europa.eu/o/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

At least one notifier has indicated that an impurity or an additive present in the substance impacts the notified classification.

Properties of concern

Regulatory context

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 8 active registrations under REACH, 1 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Registration dossiers submitted to ECHA for this substance have been evaluated under REACH.
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Persistent Organic Pollutants Regulation (POPs)

List of substances subject to the POPs Regulation:
List of substances proposed as POPs:

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Seveso Annex I:
Industrial accident prevention and reporting requirements have been established for this substance.
Notified C&L:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 000 to < 100 000 tonnes per annum.

This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is used in the following products: coating products, inks and toners, polymers and finger paints.

Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

This substance is used in the following activities or processes at workplace: high energy work-up of substances bound in materials or articles (e.g. hot rolling/forming, grinding, mechanical cutting, drilling or sanding).

Other release to the environment of this substance is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials), indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment), outdoor use in long-life materials with high release rate (e.g. tyres, treated wooden products, treated textile and fabric, brake pads in trucks or cars, sanding of buildings (bridges, facades) or vehicles (ships)) and indoor use in long-life materials with high release rate (e.g. release from fabrics, textiles during washing, removal of indoor paints).

This substance can be found in complex articles, with no release intended: vehicles. This substance can be found in products with material based on: wood (e.g. floors, furniture, toys), metal (e.g. cutlery, pots, toys, jewellery), paper (e.g. tissues, feminine hygiene products, nappies, books, magazines, wallpaper) and plastic (e.g. food packaging and storage, toys, mobile phones).

This substance is used in the following products: coating products and non-metal-surface treatment products.

This substance is used in the following areas: printing and recorded media reproduction and building & construction work. This substance is used for the manufacture of: machinery and vehicles.

This substance is used in the following activities or processes at workplace: transfer of chemicals, roller or brushing applications, treatment of articles by dipping and pouring, mixing in open batch processes, non-industrial spraying and hand mixing with intimate contact only with personal protective equipment available.

Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

This substance is used in the following products: coating products and non-metal-surface treatment products.

This substance is used in the following activities or processes at workplace: transfer of chemicals, mixing in open batch processes, laboratory work, transfer of substance into small containers, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation and batch processing in synthesis or formulation with opportunity for exposure.

Release to the environment of this substance can occur from industrial use: formulation of mixtures and formulation in materials.

This substance is used in the following products: semiconductors.

This substance is used in the following areas: formulation of mixtures and/or re-packaging and printing and recorded media reproduction. This substance is used for the manufacture of: chemicals, electrical, electronic and optical equipment and plastic products.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, laboratory work, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation and batch processing in synthesis or formulation with opportunity for exposure.

Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites, as an intermediate step in further manufacturing of another substance (use of intermediates) and in the production of articles.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure and laboratory work.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: keep away from heat, sparks, open flames and/or hot surfaces – No smoking; use non-sparking tools; ground and bond container and receiving equipment; wash parts of the body (as specified by manufacturer/supplier)in contact with substance thoroughly after handling; use explosion-proof equipment (electrical/ventilating/lighting/etc.); keep container tightly closed; avoid breathing the dust, fume, gas, mist, vapours or spray; take actions to prevent static discharges; use only outdoors or in a well-ventilated area; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier.

Response statements

In case of incident: If on skin (or hair): take off immediately all contaminated clothing. Rinse skin with water or shower. If eye irritation persists get medical advice/attention. Call a poison center or doctor/physician if you feel unwell. If inhaled: remove victim to fresh air and keep at rest in a position comfortable for breathing. In case of fire: Use (measures specified by manufacturer/supplier) for extinction. If in eyes: rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing.

Storage statements

Store this substance in a well-ventilated place and Keeping it cool; locked up; in a well-ventilated place and keeping container tightly closed.

Disposal statements

The substance must be disposed in accordance with local/regional/national/international regulation.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • INEOS nv, Haven 1053 -- Nieuwe Weg 1 2070 Zwijndrecht Belgium
  • JSR Micro n.v., Technologielaan 8 3001 Leuven Belgium
  • Milliken Europe B.V., Ham 18-24 9000 Gent Belgium
  • REACHlaw Ltd., Vänrikinkuja 3 JK 21 FI-02600 Espoo Finland
  • Shell Nederland Raffinaderij B.V., Vondelingenweg 601 Postbus 3000 3190 GA Rotterdam Netherlands Netherlands
  • Sun Chemical Nyomdafesték Kereskedelmi ès Gyarto KFT, Telek u. 7-9 H-1152 Budapest Hungary
  • TFL ITALIA SpA, Via dei Campacci 11 20010 Buscate MI Italy

Substance names and other identifiers

1-Ethoxy-2-propanol
Other
1-ethoxypropan-2-ol
EC Inventory
1-ethoxypropan-2-ol
REACH pre-registration
1-ethoxypropan-2-ol 2PG1EE 1-ethoxy-2-propanol propylene glycol monoethyl ether
C&L Inventory
1-ethoxypropan-2-ol; 2PG1EE; 1-ethoxy-2-propanol; propylene glycol monoethyl ether
Aerosols Directive - Flammable Contents - Labelling Requirements, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Regulation - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Medical Devices Regulation - Hazardous Substances, Pressure Equipment Directive - Group 1 Fluids Hazardous Substances, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties
2-Propanol, 1-ethoxy-
Other
Propylene glycol ethyl ether
Other
1-ethoxypropaan-2-ol 2PG1EE 1-ethoxy-2-propanol propyleenglycolethylether propyleenglycolmonoether (nl)
C&L Inventory
1-Ethoxypropan-2-ol 2PG1EE 1-Ethoxy-2-propanol Propylenglycol-Ethylether Propylenglycol-Monoether (de)
C&L Inventory
1-ethoxypropan-2-ol 2PG1EE propylenglycolmonoethylether (da)
C&L Inventory
1-etoksipropan-2-ol 2PG1EE 1-etoksi-2-propanol propilen glikol monoetil eter (sl)
C&L Inventory
1-Etoksipropan-2-oli 2PG1EE 1-Etoksi-2-propanoli Propyleeniglykolin monoetyylieetteri (fi)
C&L Inventory
1-etoksipropan-2-olis 2PG1EE 1-etoksi-2-propanolis propilenglikolio monoetileteris (lt)
C&L Inventory
1-etoksipropān-2-ols 2PG1EE 1-etoksi-2-propanols propilēnglikola monoetilēteris (lv)
C&L Inventory
1-etoksypropan-2-ol 1-etoksy-2-propanol 2PG1EE eter monoetylowy glikolu propylenowego (pl)
C&L Inventory
1-etoksypropan-2-ol 2PG1EE 1-etoksy-2-propanol propylenglykolmonoetyleter (no)
C&L Inventory
1-etoksüpropaan-2-ool 2PG1EE 1-etoksü-2-propanool propüleenglükoolmonoetüüleeter (et)
C&L Inventory
1-etossipropan-2-olo 2PG1EE 1-etossi-2-propanolo propilene glicol monoetiletere (it)
C&L Inventory
1-etoxi-2-propanol (sv)
C&L Inventory
1-etoxipronan-2-ol 2PG1EE 1-etoxi-2-propanol propilenglicol monoetil eter (es)
C&L Inventory
1-etoxipropan-2-ol 2PG1EE 1-etoxi-2-propanol propilen glicol monoetil eter (ro)
C&L Inventory
1-etoxipropan-2-ol 2PG1EE 1-etoxi-2-propanol propilenoglico etil éter éter etílico do propilenoglicol (pt)
C&L Inventory
1-etoxipropán-2-ol 2PG1EE 1-etoxi-2-propanol propilén-glikol-monoetil-éter (hu)
C&L Inventory
1-etoxypropán-2-ol 2PG1EE 1-etoxy-2-propanol propylénglykol-monoetyléter (sk)
C&L Inventory
1-éthoxypropan-2-ol; 2PG1EE; 1-éthoxy-2-propanol; éther monoéthylique de propylène glycol; 2PG1EE 1-éthoxy-2-propanol éther éthylique du propylène glycol éther monoéthylique du propylène glycol (fr)
C&L Inventory
1-етоксипропан-2-ол 2PG1EE 1-етокси-2-пропанол пропилeнгликол моноетилов етер (bg)
C&L Inventory
1-Ethoxy-2-propanol
C&L Inventory, Registration dossier
1-ethoxy-2-propanol; propylene glycol monoethyl ether
C&L Inventory
1-ethoxypropam-2-ol
C&L Inventory
1-ETHOXYPROPAN-2-OL
C&L Inventory, Registration dossier, Other
1-ETHOXYPROPAN-2-OL
C&L Inventory, Registration dossier, Other
1-ethoxypropan-2-ol; 2PG1EE; 1-ethoxy-2-propanol; propylene glycol monoethyl ether;
C&L Inventory
1-etossipropan-2-olo
C&L Inventory
2-Propanol, 1-ethoxy-
C&L Inventory
2PG1EE
C&L Inventory
ethoxy propanol
Registration dossier
Ethoxypropanol
C&L Inventory
Ethoxypropanol
Registration dossier
propylene glycol monoethyl ether
C&L Inventory
Propyleneglycol ethyl ether
Registration dossier
EP
Registration dossier
Ethoxy Propanol
Registration dossier
ethoxypropanol
Registration dossier
ETHYLPROXITOL
Registration dossier
PGEE
Registration dossier
propylene glycol ethyl ether
Registration dossier
1569-02-4
CAS number
EC Inventory, C&L Inventory, Registration dossier, REACH pre-registration, Other, Aerosols Directive - Flammable Contents - Labelling Requirements, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Regulation - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Medical Devices Regulation - Hazardous Substances, Pressure Equipment Directive - Group 1 Fluids Hazardous Substances, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties
603-177-00-8
Index number
C&L Inventory

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 1 study submitted
  • 1 study processed
C Physical state at 20°C and 1013 hPa
Liquid (100%) [1]
C Odour
Sweetish (100%) [1]
C Substance type
Organic (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Melting/freezing point

Study results
  • 4 studies submitted
  • 1 study processed
R Melting / freezing point
-70 °C @ 101.325 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Melting / freezing point at 101 325 Pa
-70.15 °C

Boiling point

Study results
  • 5 studies submitted
  • 1 study processed
R Boiling point
130.5 - 134.5 °C @ 101.325 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 4
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Boiling point at 101 325 Pa
131.85 °C

Density

Study results
  • 3 studies submitted
  • 1 study processed
R Density
0.888 - 0.908 g/cm³ @ 10 - 30 °C [3]

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Relative density at 20°C
897

Vapour pressure

Study results
  • 4 studies submitted
  • 1 study processed
R Vapour pressure
20.064 - 56.054 hPa @ 33.6 - 55.7 °C [4]

Type of Study provided
Studies with data
Key study 1
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Vapour pressure
10 hPa @ 23.85 °C

Partition coefficient

Study results
  • 5 studies submitted
  • 3 studies processed
R Log Pow
0 - 1.46 @ 20 °C and pH 6.8 - 7 [3]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence 2 1
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Log Kow (Log Pow)
0 @ 20 °C

Water solubility

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Water solubility
897 g/L

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Flash point

Study results
  • 2 studies submitted
  • 1 study processed
R Flash point
40 °C @ 101.325 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Flash point at 101 325 Pa
39.85 °C

Auto flammability

Study results
  • 5 studies submitted
  • 3 studies processed
R Autoflammability / self-ignition
197 - 287 °C @ 10.13 - 96.659 kPa [4]

Type of Study provided
Studies with data
Key study 1 1
Supporting study 1
Weight of evidence 2
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Flammability

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Explosiveness

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Oxidising

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 1 study submitted
  • 1 study processed
C Dissociating properties
No (100%) [1]
R Dissociation constant
14.98 @ 25 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
pKa at 20 °C
15

Viscosity

Study results
  • 1 study submitted
  • 1 study processed
R kinematic viscosity (in mm²/s)
1.513 - 4.498 [5]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Dynamic viscosity at 20 °C
2.21 mPa.s

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Hydrolysis

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Phototransformation in water

Data not provided by the registrant

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Study results
  • 2 studies submitted
  • 2 studies processed
C Interpretation of results
Readily biodegradable (100%) [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Biodegradation in water
Readily biodegradable (100%)

Biodegradation in water & sediment - simulation tests

Data not provided by the registrant

Biodegradation in soil

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Bioaccumulation: aquatic / sediment

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Henrys law constant (H)

Data not provided by the registrant

Distribution modelling

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers

No summary exists for this scientific endpoint

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 1 summary submitted
  • 1 summary processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater 10 mg/L (1)
Intermittent releases (freshwater) 19 mg/L (1)
Marine water 1 mg/L (1)
Intermittent releases (marine water) -
Sewage treatment plant (STP) 1.25 g/L (1)
Sediment (freshwater) 37.6 mg/kg sediment dw (1)
Sediment (marine water) 3.76 mg/kg sediment dw (1)
Hazard for Air
Air No hazard identified (1)
Hazard for Terrestrial Organism
Soil 1.97 mg/kg soil dw (1)
Hazard for Predators
Secondary poisoning 142 mg/kg food (1)

Short–term toxicity to fish

Study results
  • 6 studies submitted
  • 5 studies processed
P/RResults
LC50 (4 days) 560 - 10 000 mg/L [5]
LC0 (4 days) 200 - 4 640 mg/L [2]
LC100 (4 days) 10 g/L [2]
EC50 (4 days) 180 - 320 mg/L [1]
NOEC (4 days) 180 - 4 640 mg/L [3]

Type of Study provided
Studies with data
Key study 1 1
Supporting study
Weight of evidence 3 1
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Short–term toxicity to aquatic invertebrates

Study results
  • 5 studies submitted
  • 4 studies processed
P/RResults
EC50 (48 h) 1 g/L [1]
LC50 (48 h) 2.5 - 25.9 g/L [3]
LC0 (48 h) 1.412 g/L [1]
LC100 (48 h) 50 g/L [2]
NOEC (48 h) 560 - 1 412 mg/L [2]

Type of Study provided
Studies with data
Key study 1 1
Supporting study
Weight of evidence 2 1
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 3 studies submitted
  • 1 study processed
P/RResults
NOEC (21 days) 180 mg/L [1]
EC50 (21 days) 180 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence 1
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic algae and cyanobacteria

Study results
  • 6 studies submitted
  • 4 studies processed
P/RResults
EC50 (7 days) 1 g/L [1]
EC50 (4 days) 1.466 g/L [1]
EC50 (72 h) 100 - 3 440 mg/L [2]
EC50 (48 h) 1 - 5.583 g/L [2]
EC50 (24 h) 100 mg/L [1]

Type of Study provided
Studies with data
Key study 1 1
Supporting study 1
Weight of evidence 3
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
EC50 for freshwater algae
1.9 g/L
EC10 or NOEC for freshwater algae
500 mg/L

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Study results
  • 1 study submitted
  • 1 study processed
P/RResults
EC10 (16 h) 4.6 g/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Sediment toxicity

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial arthropods

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial plants

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to soil microorganisms

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to birds

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 1 summary submitted
  • 1 summary processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 106 mg/m³ repeated dose toxicity
Acute /short term: (DNEL) 500 mg/m³ repeated dose toxicity
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 74 mg/kg bw/day repeated dose toxicity
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
EYE Exposure
Medium hazard (no threshold derived)
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 127 mg/m³ repeated dose toxicity
Acute /short term: (DNEL) 300 mg/m³ repeated dose toxicity
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 44.3 mg/kg bw/day repeated dose toxicity
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 14 mg/kg bw/day repeated dose toxicity
Acute /short term: No hazard identified
EYE Exposure
Medium hazard (no threshold derived)

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study 1
Supporting study 4
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal absorption
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Acute toxicity

Study results
oral
  • 1 study submitted
  • 1 study processed
P/RResults
LD50 2 mL/kg bw (rat) [1]
LD0 2 mL/kg bw (rat) [1]
M/CInterpretations of results
Not classified [1]

Type of Study provided
oral
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
inhalation
  • 2 studies submitted
  • 1 study processed
P/RResults
LC50 (4 h) 9.59 mg/L air (rat) [1]
LC0 (4 h) 9.59 mg/L air (rat) [1]
M/CInterpretations of results
Not classified [1]

inhalation
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
dermal
  • 4 studies submitted
  • 3 studies processed
P/RResults
LD50 2 000 mg/kg bw (rat) [1]
LD0 2 009 mg/kg bw (rat) [2]
M/CInterpretations of results
Not classified [3]

dermal
Studies with data
Key study 3 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
other routes
  • 0 studies submitted
  • 0 studies processed

No data available

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Irritation / corrosion

Study results
Study data: skin
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: eye
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin
No adverse effect observed (not irritating)
Eye
Adverse effect observed (irritating)

Sensitisation

Study results
Study data: skin
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1 1
Supporting study
Weight of evidence 1
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin sensitisation
No adverse effect observed (not sensitising)

Repeated dose toxicity

Study results
Study data: oral
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Study data: oral
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: inhalation
  • 2 studies submitted
  • 1 study processed
P/RResults
NOAEC (rat): 1.266 mg/L air [1]
LOAEC (rat): 8.36 mg/L air [1]

Study data: inhalation
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal
  • 2 studies submitted
  • 1 study processed
P/RResults
NOAEL (rabbit): 1 800 mg/kg bw/day [1]

Study data: dermal
Studies with data
Key study 1 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Genetic toxicity

Study results
Study data: in vitro
  • 9 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 4 1
Supporting study 2 2
Weight of evidence
Other
Data waiving
no waivers
Study data: in vivo
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Carcinogenicity

Data not provided by the registrant

Toxicity to reproduction

Study results
Study data: reproduction
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 1 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Study data: developmental
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Neurotoxicity

Data not provided by the registrant

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant