Registration Dossier
Registration Dossier
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EC number: - | CAS number: -
Endpoint summary
Administrative data
Description of key information
To assess the short-term toxicity of the registered substance to aquatic organisms, experimental studies of reliability 1 (Klimisch rating), are available on two trophic levels: algae and aquatic invertebrates. The results were the following:
48h-EC50 (Daphnia magna) > 100 mg/L; OECD TG 202 and EU Method C.2
These results were found when testing the algae Raphidocelis subcapitata for 72 hours:
Growth rate:
EC10: 15 mg/L
EC50: 25 mg/L
Yield:
EC10: 11 mg/L
EC50: 17 mg/L
LOEC = 32 mg/L; NOEC = 10 mg/L
(OECD 201 and EU Method C.3, with GLP compliance)
Additional information
The two studies fulfilled the requirements of REACH Annex VII 9.1.1 (short-term toxicity to aquatic invertebrates (Daphnia) test) and 9.1.2 (Aquatic plant growth inhibition (algae) test).
In the aquatic invertebrate test Daphnia were exposed for 48 hours to a range of concentrations of the test substance (10, 18, 32, 56 and 100 mg/L), their immobilisation and sub-lethal effects were observed. No significant effects were present in any concentrations, therefore the NOEC for this endpoint was established as 100 mg/L.
The substance showed higher toxicity to algae (Raphidocelis subcapitata). In this test the algae were exposed to a range of concentrations of the substance (1.0, 10 and 100 mg/L in the range finding test, 0.32, 1.0, 3.2, 10, 32 and 100 mg/L in the definite test) for 72 hours. The cell densities were measured and from this the growth rate and yield were established. The results are summarised in the section above, the LOEC was established to be 32 mg/L and the NOEC 10 mg/L.
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