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Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 21 January 2021 to 26 January 2021
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Remarks:
- Vapour pressure was determined in the melting point range, so it is not known which form the vapour pressure measurement was taken. Overall the study was performed in accordance with the guideline and documented in sufficient detail, so this restriction in reliability is considered to be acceptable.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Version / remarks:
- 2006
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Version / remarks:
- 2008
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- effusion method: vapour pressure balance
- Key result
- Temp.:
- 25 °C
- Vapour pressure:
- 0.002 Pa
- Conclusions:
- The vapour pressure of the test item has been determined to be 0.00237 Pa at 25 °C.
- Executive summary:
The vapor pressure of the test item has been determined to be 2.37 x 10-3 Pa at 25 °C, using the vapor pressure balance method, designed to be compatible with Method A.4 Vapour Pressure of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 104 of the OECD Guidelines for Testing of Chemicals, 23 March 2006.
Reference
A total of 10 runs were performed for the main sequence, the mass readings achieved during these runs was very low thus producing graphs for extrapolation at the limit of the instrument. Runs 1 and 2 have not been reported as equilibration/degassing was still in progress, runs 6 and 7 have not been reported as the graphs produced were truly non-linear. Equilibrium has been achieved over the reported runs which have been used to calculate the vapor pressure of the test item. The use of these reported runs is considered more accurate than the in-house estimation method.
The results may represent rounded values obtained by calculations based on the exact raw data.
Recorded temperatures, mass differences and the resulting calculated values of vapour pressure are shown in the following tables:
Run 3
Table 1 - Vapour Pressure Data
Temperature (°C) | Temperature (K) | Reciprocal Temperature (K-1) | Mass Difference (µg) | Mass Difference (kg) | Vapour Pressure (Pa) | Log10 Vp |
36 | 309.15 | 0.003235 | 7.93 | 7.93e-09 | 0.01101 | -1.95821 |
37 | 310.15 | 0.003224 | 8.56 | 8.56e-09 | 0.01188 | -1.92518 |
38 | 311.15 | 0.003214 | 8.73 | 8.73e-09 | 0.01212 | -1.91650 |
39 | 312.15 | 0.003204 | 8.70 | 8.70e-09 | 0.01208 | -1.91793 |
40 | 313.15 | 0.003193 | 13.76 | 1.376e-08 | 0.01910 | -1.71897 |
41 | 314.15 | 0.003183 | 12.30 | 1.230e-08 | 0.01708 | -1.76751 |
42 | 315.15 | 0.003173 | 13.67 | 1.367e-08 | 0.01898 | -1.72170 |
43 | 316.15 | 0.003163 | 11.43 | 1.143e-08 | 0.001587 | -1.79942 |
44 | 317.15 | 0.003153 | 17.99 | 1.799e-08 | 0.02397 | -1.60258 |
45 | 318.15 | 0.003143 | 17.02 | 1.702e-08 | 0.02363 | -1.62654 |
46 | 319.15 | 0.003133 | 17.84 | 1.784e-08 | 0.02477 | -1.60607 |
A plot of Log10 (vapor pressure (Pa)) versus reciprocal temperature (1/T(K)) for Run 3 gives the following statistical data using an unweighted least squares treatment.
Slope: -3.70 x 103
Standard error in slope: 520
Intercept: 9.99
Standard error in intercept: 1.66
The results obtained indicate the following vapor pressure relationship:
Log10 (Vp (Pa)) = -3.70 x 103/temp(K) + 9.99
The above yields a vapor pressure (Pa) at 298.15 K with a common logarithm of -2.41.
Run 4
Table 2 - Vapour Pressure Data
Temperature (°C) | Temperature (K) | Reciprocal Temperature (K-1) | Mass Difference (µg) | Mass Difference (kg) | Vapour Pressure (Pa) | Log10 Vp |
36 | 309.15 | 0.003235 | 6.60 | 6.60e-09 | 0.00916 | -2.03810 |
37 | 310.15 | 0.003224 | 7.04 | 7.04e-09 | 0.00977 | -2.01011 |
38 | 311.15 | 0.003214 | 10.46 | 1.046e-08 | 0.01452 | -1.83803 |
39 | 312.15 | 0.003204 | 6.04 | 6.04e-09 | 0.00839 | -2.07624 |
40 | 313.15 | 0.003193 | 9.17 | 9.17e-09 | 0.01273 | -1.89517 |
41 | 314.15 | 0.003183 | 10.53 | 1.053e-08 | 0.01462 | -1.83505 |
42 | 315.15 | 0.003173 | 10.98 | 1.098e-08 | 0.01524 | -1.81702 |
43 | 316.15 | 0.003163 | 13.03 | 1.303e-08 | 0.001809 | -1.74256 |
44 | 317.15 | 0.003153 | 14.73 | 1.473e-08 | 0.02045 | -1.68931 |
45 | 318.15 | 0.003143 | 18.65 | 1.865e-08 | 0.02589 | -1.58687 |
46 | 319.15 | 0.003133 | 14.97 | 1.497e-08 | 0.02078 | -1.68235 |
A plot of Log10 (vapor pressure (Pa)) versus reciprocal temperature (1/T(K)) for Run 4 gives the following statistical data using an unweighted least squares treatment.
Slope: -4.17 x 103
Standard error in slope: 705
Intercept: 11.4
Standard error in intercept: 2.24
The results obtained indicate the following vapor pressure relationship:
Log10 (Vp (Pa)) = -4.17 x 103/temp(K) + 11.4
The above yields a vapor pressure (Pa) at 298.15 K with a common logarithm of -2.55.
Run 5
Table 3 - Vapour Pressure Data
Temperature (°C) | Temperature (K) | Reciprocal Temperature (K-1) | Mass Difference (µg) | Mass Difference (kg) | Vapour Pressure (Pa) | Log10 Vp |
36 | 309.15 | 0.003235 | 6.38 | 6.83e-09 | 0.00886 | -2.05257 |
37 | 310.15 | 0.003224 | 5.66 | 5.66e-09 | 0.00786 | -2.10458 |
38 | 311.15 | 0.003214 | 4.68 | 4.68e-08 | 0.00650 | -2.18709 |
39 | 312.15 | 0.003204 | 4.82 | 4.82e-09 | 0.00669 | -2.17457 |
40 | 313.15 | 0.003193 | 6.83 | 6.83e-09 | 0.00948 | -2.02319 |
41 | 314.15 | 0.003183 | 6.75 | 6.75e-09 | 0.00937 | -2.02826 |
42 | 315.15 | 0.003173 | 7.54 | 7.54e-09 | 0.01047 | -1.98005 |
43 | 316.15 | 0.003163 | 17.63 | 1.763e-08 | 0.02447 | -1.61137 |
44 | 317.15 | 0.003153 | 12.29 | 1.299e-08 | 0.01706 | -1.76802 |
45 | 318.15 | 0.003143 | 10.41 | 1.041e-08 | 0.01445 | -1.84013 |
46 | 319.15 | 0.003133 | 15.49 | 1.549e-08 | 0.02150 | -1.66756 |
A plot of Log10 (vapor pressure (Pa)) versus reciprocal temperature (1/T(K)) for Run 5 gives the following statistical data using an unweighted least squares treatment.
Slope: -4.82 x 103
Standard error in slope: 1.18 x 103
Intercept: 13.4
Standard error in intercept: 3.56
The results obtained indicate the following vapor pressure relationship:
Log10 (Vp (Pa)) = -4.82 x 103/temp(K) + 13.4
The above yields a vapor pressure (Pa) at 298.15 K with a common logarithm of -2.77.
Run 8
Table 4 - Vapour Pressure Data
Temperature (°C) | Temperature (K) | Reciprocal Temperature (K-1) | Mass Difference (µg) | Mass Difference (kg) | Vapour Pressure (Pa) | Log10 Vp |
36 | 309.15 | 0.003235 | 4.59 | 4.59e-09 | 0.00637 | -2.19586 |
37 | 310.15 | 0.003224 | 3.28 | 3.28e-09 | 0.00455 | -2.34199 |
38 | 311.15 | 0.003214 | 4.89 | 4.89e-09 | 0.00679 | -2.16813 |
39 | 312.15 | 0.003204 | 4.74 | 4.74e-09 | 0.00658 | -2.18177 |
40 | 313.15 | 0.003193 | 8.44 | 8.44e-09 | 0.01172 | -1.93107 |
41 | 314.15 | 0.003183 | 9.60 | 9.60e-09 | 0.01333 | -1.87517 |
42 | 315.15 | 0.003173 | 7.92 | 7.92e-09 | 0.01099 | -1.95900 |
43 | 316.15 | 0.003163 | 8.79 | 8.79e-09 | 0.01220 | -1.91364 |
44 | 317.15 | 0.003153 | 7.48 | 7.48e-09 | 0.01038 | -1.98380 |
45 | 318.15 | 0.003143 | 8.82 | 8.82e-09 | 0.01224 | -1.91222 |
46 | 319.15 | 0.003133 | 8.69 | 8.69e-09 | 0.01206 | -1.91865 |
A plot of Log10 (vapor pressure (Pa)) versus reciprocal temperature (1/T(K)) for Run 8 gives the following statistical data using an unweighted least squares treatment.
Slope: -3.74 x 103
Standard error in slope: 928
Intercept: 987
Standard error in intercept: 2.96
The results obtained indicate the following vapor pressure relationship:
Log10 (Vp (Pa)) = -3.74 x 103/temp(K) + 9.87
The above yields a vapor pressure (Pa) at 298.15 K with a common logarithm of -2.67.
Run 9
Table 5 - Vapour Pressure Data
Temperature (°C) | Temperature (K) | Reciprocal Temperature (K-1) | Mass Difference (µg) | Mass Difference (kg) | Vapour Pressure (Pa) | Log10 Vp |
36 | 309.15 | 0.003235 | 5.11 | 5.11e-09 | 0.00709 | -2.14935 |
37 | 310.15 | 0.003224 | 3.21 | 3.21e-09 | 0.00446 | -2.35067 |
38 | 311.15 | 0.003214 | 4.80 | 4.80e-09 | 0.00666 | -2.17653 |
39 | 312.15 | 0.003204 | 1.63 | 1.63e-09 | 0.00226 | -2.64589 |
40 | 313.15 | 0.003193 | 5.30 | 5.30e-09 | 0.00736 | -2.13312 |
41 | 314.15 | 0.003183 | 3.52 | 3.52e-09 | 0.00489 | -2.31069 |
42 | 315.15 | 0.003173 | 5.17 | 5.17e-09 | 0.00718 | -2.14388 |
43 | 316.15 | 0.003163 | 4.02 | 4.20e-09 | 0.00558 | -2.25337 |
44 | 317.15 | 0.003153 | 6.63 | 6.63e-09 | 0.00920 | -2.03621 |
45 | 318.15 | 0.003143 | 7.35 | 7.35e-09 | 0.01020 | -1.99140 |
46 | 319.15 | 0.003133 | 8.69 | 8.69e-09 | 0.01206 | -1.91865 |
A plot of Log10 (vapor pressure (Pa)) versus reciprocal temperature (1/T(K)) for Run 9 gives the following statistical data using an unweighted least squares treatment.
Slope: -3.37 x 103
Standard error in slope: 1.61 x 103
Intercept: 8.54
Standard error in intercept: 5.14
The results obtained indicate the following vapor pressure relationship:
Log10 (Vp (Pa)) = -3.37 x 103/temp(K) + 8.54
The above yields a vapor pressure (Pa) at 298.15 K with a common logarithm of -2.77.
Run 10
Table 6 - Vapour Pressure Data
Temperature (°C) | Temperature (K) | Reciprocal Temperature (K-1) | Mass Difference (µg) | Mass Difference (kg) | Vapour Pressure (Pa) | Log10 Vp |
36 | 309.15 | 0.003235 | 2.78 | 2.78e-09 | 0.00386 | -2.41341 |
37 | 310.15 | 0.003224 | 2.47 | 2.47e-09 | 0.00343 | -2.46471 |
38 | 311.15 | 0.003214 | 4.33 | 4.33e-09 | 0.00601 | -2.22113 |
39 | 312.15 | 0.003204 | 4.54 | 4.54e-09 | 0.00630 | -2.20066 |
40 | 313.15 | 0.003193 | 3.26 | 3.26e-09 | 0.00453 | -2.34390 |
41 | 314.15 | 0.003183 | 4.99 | 4.99e-09 | 0.00693 | -2.15927 |
42 | 315.15 | 0.003173 | 4.05 | 4.05e-09 | 0.00562 | -2.25026 |
43 | 316.15 | 0.003163 | 3.87 | 3.87e-09 | 0.00537 | -2.27003 |
44 | 317.15 | 0.003153 | 3.99 | 3.99e-09 | 0.00554 | -2.25649 |
45 | 318.15 | 0.003143 | 4.52 | 4.52e-09 | 0.00627 | -2.0273 |
46 | 319.15 | 0.003133 | 4.75 | 4.75e-09 | 0.00659 | -2.18111 |
A plot of Log10 (vapor pressure (Pa)) versus reciprocal temperature (1/T(K)) for Run 10 gives the following statistical data using an unweighted least squares treatment.
Slope: -1.84 x 103
Standard error in slope: 751
Intercept: 3.59
Standard error in intercept: 2.39
The results obtained indicate the following vapor pressure relationship:
Log10 (Vp (Pa)) = -1.84 x 103/temp(K) + 3.59
The above yields a vapor pressure (Pa) at 298.15 K with a common logarithm of -2.58.
The values of vapour pressure at 25°C, extrapolated from each graph, are summarised in the following table:
Table 7: Summary of Vapour Pressure Data
Run | Log10[Vp(25°C)] |
3 | -2.41 |
4 | -2.55 |
5 | -2.77 |
8 | -2.67 |
9 | -2.77 |
10 | -2.58 |
Mean | -2.63 |
Description of key information
2.37 x 10-3 Pa at 25°C; Ford, A. J. (2021)
Key value for chemical safety assessment
- Vapour pressure:
- 0.002 Pa
- at the temperature of:
- 25 °C
Additional information
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