Registration Dossier
Registration Dossier
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EC number: 269-102-2 | CAS number: 68187-50-8 This substance is identified in the Colour Index by Colour Index Constitution Number, C.I. 77498.
Endpoint summary
Administrative data
Description of key information
There is no study available with the target substance. In a study similar to OECD TG 423 performed with the structural analogue substance Iron cobalt chromite black spinel a discriminating dose > 2000 mg/kg bw in rats was observed.
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
- Dose descriptor:
- discriminating dose
- Value:
- 2 000 mg/kg bw
- Quality of whole database:
- similar to OECD TG 423 (Read Across)
Acute toxicity: via inhalation route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Acute toxicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
Oral
In an acute oral toxicity study similar to OECD TG 423, Sprague Dawley rats (3 males + 3 females) were given a single oral dose of the structural analogue substance Iron cobalt chromite black spinel (2000 mg/kg bw). Animals were observed for 14 days and necropsy was performed. All animals survived until the end of the observation period. Neither abnormal effects nor any toxicity signs that could be attributed to the test item were observed. The body weight gain of the treated animals was similar to that of control animals. At necropsy no substance-related signs of toxicity were detected. The discriminating dose was > 2000 mg/kg bw ( Laboratorio de análisis Dr. Echevarne-Laboratorio, 2003).
Justification for classification or non-classification
Classification, Labelling, and Packaging Regulation (EC) No 1272/2008
The available experimental test data is reliable and suitable for classification purposes under Regulation (EC) No 1272/2008. As a result the substance is not considered to be classified for acute toxicity under Regulation (EC) No 1272/2008, as amended for the tenth time in Regulation (EU) No 2017/776.
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