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EC number: 202-716-0
CAS number: 98-95-3
Upon inhalative exposure of 7 persons to nitrobenzene vapour
(5 to 30 µg/L) for 6 hours, retention in the lungs was found
to be in average 80% (exposure diminished from 87% to
73% during the 6 -hour exposure, indicating a low rate of conversion of nitrobenzene
in the body taht leads to blodd saturation). Urine was tested for p-aminophenol and
p-nitrophenol; only the latter was found. It represented in
average about 13 to 16% of the retained dose with very
variable individual results (6 to 37%). Excretion was
maximal at the end of the exposure period and proceeded very slowly
(half life of about 5 and > 70 h). In some cases, p-nitrophenol could be detected in
the urine after more than 100 hours. In the
investigated dose range an average of 6 to 22% of the dose is excreted in
the urine as p-nitrophenol.
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