Registration Dossier
Registration Dossier
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EC number: 200-860-9 | CAS number: 75-31-0
Endpoint summary
Administrative data
Description of key information
Relevant key information is given in the endpoint summaries on the respective properties.
For a summary and conclusion with regard to overall environmental fate properties, please see below!
Additional information
Summary "Environmental fate and pathways"
Isopropylamine has no intrinsic persistent or bioaccumulating properties:
In a valid standard ready biodegradability study according to OECD 301F, 72% biodegradation (O2 consumption) of test substance were observed within 28 days (BASF 1997; KS). This result is supported by a ready biodegradability study conducted according to OECD 301A, where 95% biodegradation (DOC) occurrerd within 21 days (Arkema 1992). Furthermore, a study for inherent biodegradability confirms the ready biodegradability of the test substance since biodegradation >83% (COD) within 5 days and >95% (COD) within 10 d were observed (Hoechst 1980).
No data from simulation tests on biodegradability in water, sediment or soil are available.
Based on model calculations, the half-life time of isopropylamine is supposed to be about 10 h in air due to OH radical-induced photolysis.
No bioaccumulation potential is expected in aquatic organisms, given the low logPow of < 1 and the short residence time in the environment. Based on the low soil adsorption potential determined for the close structural analogue n-butylamine in read-across (Koc = 43.2 L/kg; von Oepen et al. 1991), isopropylamine will not partition to any relevant extent to the solids phase. Accordingly and considering in addition the ready biodegradability of the submission substance, any potential for accumulation in soil can safely be excluded.
With a pKa of 10.8, isopropylamine as a strong base will exist predominantly in its protonated form in the environment, and the protonated form of isopropylamine is not expected to volatilize from water or moist soil surfaces based on a Henry's law constant of 0.001615 Pa*m^3/mol at pH 7 (25 °C; FoBiG 2019).
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