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Diss Factsheets
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EC number: 216-343-6 | CAS number: 1562-00-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Dissociation constant
Administrative data
Link to relevant study record(s)
Description of key information
Experimental data could not be determined according to OECD guideline 112.
Calculated results:
pKa1 = 15.10 ± 0.10, pKa1 is associated with the hydroxyl group.
pKa2 = 1.39 ± 0.50, pKa2 is associated with the sulfonic acid function.
Key value for chemical safety assessment
Additional information
A guideline study (OECD 112) did not deliver results for the dissociation constants of sodium 2 -hydroxyethanesulphonate. Therefore, a calculation was performed for the corresponding 2-hydroxyethanesulphonic acid with a commercially available software tool. Two values for the two functional groups were predicted. Each value is provided with its 95% confidence limits:
pKa1 = 15.10 ± 0.10, pKa1 is associated with the hydroxyl group.
pKa2 = 1.39 ± 0.50, pKa2 is associated with the sulfonic acid function.
The calculated data are consistent with what would be expected for the functional groups present in the molecule.
From this data it can be concluded that under environmental relevant conditions 2 -hydroxyethanesulphonic acid exists only in its single ionized form, represented by the hydroxysulfonate anion.
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