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Physical & Chemical properties

Vapour pressure

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Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
from 2021-11-26 to 2022-01-11
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Version / remarks:
2009
Deviations:
no
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Version / remarks:
2006
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
effusion method: Knudsen cell
Key result
Temp.:
25 °C
Vapour pressure:
2.751 Pa
Key result
Temp.:
20 °C
Vapour pressure:
2.184 Pa

The vapour pressure was measured in the temperature range of 30 to 45 °C. The evaluation of the vapour pressure was performed in the range of 30 to 45 °C.













































Table: Results of the Effusion method



Temperature, °C



Δm/Δt, mg/min



Vapour pressure, Pa



 



30.1



1.7795 x 10-2



3.7057



 



33.0



1.8309 x 10-2



3.8311



 



36.2



1.9417 x 10-2



4.0841



 



39.3



2.4375 x 10-2



5.1524



 



45.2



3.1644 x 10-2



6.7519



 



 





















Table: Regression data of the vapour pressure curve - Regression output



Intercept



Slope



R. Squared



 



6.3169



-1752.3564



0.9363



 


Conclusions:
The vapour pressure of the test item at 25 °C was determined to be 2.7506 Pa.
Executive summary:

An experimental study was conducted to determine the vapour pressure of the test item according to EU Method A.4. and OECD Test Guideline 104 using the Knudsen cell. The vapour pressure at 20 and 25 °C was extrapolated from the linear regression of the vapour pressure curve of the measurements performed in the range of 30 to 45 °C. The vapour pressure of the test item at 20 and 25 °C was determined to be 2.1837 and 2.7506 Pa, respectively.

Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
comparable to guideline study with acceptable restrictions
Qualifier:
equivalent or similar to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Deviations:
not specified
GLP compliance:
no
Type of method:
other: not specified
Test no.:
#1
Temp.:
25 °C
Vapour pressure:
2.5 Pa
Conclusions:
The vapour pressure of Incozol 2 was determined to be 2.5 Pa at 25 °C.

Description of key information

The vapour pressure of the test item at 25 °C was determined to be 2.7506 Pa.

Key value for chemical safety assessment

Vapour pressure:
2.751 Pa
at the temperature of:
25 °C

Additional information

An experimental study was conducted to determine the vapour pressure of the test item according to EU Method A.4. and OECD Test Guideline 104 using the Knudsen cell. The vapour pressure at 20 and 25 °C was extrapolated from the linear regression of the vapour pressure curve of the measurements performed in the range of 30 to 45 °C. The vapour pressure of the test item at 20 and 25 °C was determined to be 2.1837 and 2.7506 Pa, respectively.


The vapour pressure is supported by company data without detailed documentation. In the SDS the vapour pressure is reported as 2.5 Pa at 25 °C.