Registration Dossier

Administrative data

Link to relevant study record(s)

Description of key information

Tissue accumulation and retention of radioactivity was minimal, indicating complete clearance of the administered dose.

Key value for chemical safety assessment

Additional information

The RDP was used to form a prediction of metabolism and toxicokinetics for BDP via Read-cross route.       

Both Resorcinol bis-diphenylphosphate (RDP) CAS No. 125997-21-9, 57583-54-7 and Bisphenol A bis-diphenylphosphate (BDP) CAS No. 5945-33-5, 181028-79-5 which may be used to replace the flame retardant decabromodiphenyl ether (Deca-BDE) in electronic enclosures due to lower toxicity effects on human health and large chunks of tonnes are used to produce non-halogenated flame retardants such as Bisarylphosphates. These two substances have the analogous structure and functional groups which are considered have similar biophysicochemical property and metabolites in both rodent and non-rodent animals, therefore the toxicokinetics model which were contributed from RDP can be used to elicit a prediction of ADME for BDP.