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Registration Dossier
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EC number: 269-198-6 | CAS number: 68189-42-4
Surface tension
Administrative data
- Endpoint:
- surface tension
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 17 November 2020
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 020
- Report date:
- 2020
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.5 (Surface Tension)
- Version / remarks:
- Regulation EC No. 440/2008
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 115 (Surface Tension of Aqueous Solutions)
- Version / remarks:
- 1995
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- ring method
Test material
- Reference substance name:
- Methanol
- EC Number:
- 200-659-6
- EC Name:
- Methanol
- Cas Number:
- 67-56-1
- Molecular formula:
- CH4O
- IUPAC Name:
- methanol
- Reference substance name:
- Acetone
- EC Number:
- 200-662-2
- EC Name:
- Acetone
- Cas Number:
- 67-64-1
- Molecular formula:
- C3H6O
- IUPAC Name:
- acetone
- Reference substance name:
- Water
- EC Number:
- 231-791-2
- EC Name:
- Water
- Cas Number:
- 7732-18-5
- Molecular formula:
- H2O
- IUPAC Name:
- Oxidane
- Reference substance name:
- p-nitrophenyl dihydrogen phosphate, compound with 2-amino-2-(hydroxymethyl)propane-1,3-diol (1:2)
- EC Number:
- 269-198-6
- EC Name:
- p-nitrophenyl dihydrogen phosphate, compound with 2-amino-2-(hydroxymethyl)propane-1,3-diol (1:2)
- Cas Number:
- 68189-42-4
- Molecular formula:
- C6H6NO6P.2C4H11NO3
- IUPAC Name:
- 4-nitrophenyl dihydrogen phosphate - 2-amino-2-(hydroxymethyl)propane-1,3-diol (1:2)
- Test material form:
- solid
- Details on test material:
- Batch / Lot No. 46587100
impurity 1
impurity 2
impurity 3
Constituent 1
- Specific details on test material used for the study:
- Batch No.: 46587100
Storage: Refrigerator (approx. 2-8°C)
Results and discussion
Surface tension
- Key result
- Surface tension:
- 72.1 mN/m
- Temp.:
- 20 °C
- Conc.:
- 1 g/L
- Remarks on result:
- other: overall mean of first measurement (6 values measured) and second measurement (6 values measured) concentration refers to nominal concentration of the test item
Any other information on results incl. tables
The detailed results of two measurements are summarized in the table below.
Value No. | 1st Measurement (8 min after preparing the solution) s [mN/m] | 2nd Measurement (25 min after preparing the solution) s [mN/m] |
1 | 72.01 | 72.15 |
2 | 72.02 | 72.16 |
3 | 72.02 | 72.14 |
4 | 72.02 | 72.15 |
5 | 72.01 | 72.15 |
6 | 72.01 | 72.15 |
Mean value of the individual values | 72.02 ± <0.01 | 72.15 ± <0.01 |
Total mean value | 72.08 ± 0.07 | |
Applicant's summary and conclusion
- Conclusions:
- According to OECD Test Guideline 115 and Regulation (EC) No. 440/2008 Part A Method A.5. the surface tension at 20 °C and at a concentration of 1 g/L of test item 4-NPP, di-TRIS (CAS no. 68189-42-4) in water was determined to be 72.1 mN/m. According to regulation (EC) No. 440/2008 Part A Method A.5 substances showing a surface tension lower than 60 mN/m under the conditions of method A.5 should be regarded as being surface active materials.
Thus, the test item is not regarded as surface active material. - Executive summary:
According to OECD Test Guideline 115 and Regulation (EC) No. 440/2008 Part A Method A.5. the surface tension at 20 °C and at a concentration of 1 g/L of test item 4-NPP, di-TRIS (CAS no. 68189-42-4) in water was determined to be 72.1 mN/m. According to Regulation EC No. 440/2008 Part A Method A.5. the test item is not to be regarded as surface active material.
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