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Diss Factsheets
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EC number: 201-762-9 | CAS number: 87-66-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Appearance / physical state / colour
Administrative data
- Endpoint:
- appearance / physical state / colour
- Type of information:
- other: observation
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- Final Report on the Safety Assessment of Pyrogallol
- Author:
- CIR - COSMETIC INGREDIENT REVIEW
- Year:
- 1 991
- Bibliographic source:
- JOURNAL OF THE AMERICAN COLLEGE OF TOXICOLOGY. 10(1): 67-85
Materials and methods
Test guideline
- Qualifier:
- no guideline required
- Principles of method if other than guideline:
- - Principle of test:
There is no guideline method for this endpoint. Data presented based on visual observation (supported by data on melting point)
- Short description of test conditions: an observation at standard temperature and pressure was performed.
- Parameters analysed / observed: physical state, color and odor of the substance. - GLP compliance:
- not specified
- Other quality assurance:
- other: not specified
- Remarks:
- primary source: WINDHOLZ, M., BUDVARI, S., BLUMETTI, R.F., and OTTERBEIN, F.A. 119831. The Merck Index, 10th ed. Rahway, NJ: Merck and Co., Inc., p, 1154
Test material
- Reference substance name:
- Pyrogallol
- EC Number:
- 201-762-9
- EC Name:
- Pyrogallol
- Cas Number:
- 87-66-1
- Molecular formula:
- C6H6O3
- IUPAC Name:
- benzene-1,2,3-triol
- Reference substance name:
- unknown impurities
- IUPAC Name:
- unknown impurities
- Test material form:
- not specified
- Details on test material:
- not specified
Constituent 1
impurity 1
- Specific details on test material used for the study:
- SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: not specified
- Expiration date of the lot/batch: not specified
- Purity test date: not specified
RADIOLABELLING INFORMATION (if applicable) not applicable
- Radiochemical purity: -
- Specific activity: -
- Locations of the label: -
- Expiration date of radiochemical substance: -
STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: not specified
- Stability under test conditions: not specified
- Solubility and stability of the test substance in the solvent/vehicle: not specified
- Reactivity of the test substance with the solvent/vehicle of the cell culture medium: not specified
TREATMENT OF TEST MATERIAL PRIOR TO TESTING
- Treatment of test material prior to testing: not relevant
- Preliminary purification step (if any): not specified
- Final dilution of a dissolved solid, stock liquid or gel: not relevant
- Final preparation of a solid: not relevant
FORM AS APPLIED IN THE TEST (if different from that of starting material) solid
TYPE OF BIOCIDE/PESTICIDE FORMULATION (if applicable) not applicable
OTHER SPECIFICS: Pyrogallol consists of a minimum of 99% Pyrogallol.
A UV spectral analysis of chemically pure (99%) Pyrogallol, 0.1% w/v in methanol, showed a single absorbance maximum at 267.5 nm
Results and discussion
- Physical state at 20°C and 1013 hPa:
- solid
Form / colour / odour
- Key result
- Form:
- solid: crystalline
- Remarks:
- (crystals)
- Colour:
- white
- Odour:
- odourless
- Substance type:
- organic
Applicant's summary and conclusion
- Conclusions:
- Pyrogallol is an organic solid and ordorless at standard temperature and pressure.
- Executive summary:
Pyrogallol is an organic solid and ordorless at standard temperature and pressure (@20°C and 1013 hPa).
No information on data or the test method used to measure this endpoint are available in the handbook. However, this information is taken from a peer reviewed handbook (primary source: The Merck Index, 10th ed) and mentioned in a high quality review so, it can be considered reliable and suitable for use as the key study for this endpoint
.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.