Registration Dossier
Registration Dossier
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EC number: 246-874-9 | CAS number: 25340-17-4
Endpoint summary
Administrative data
Key value for chemical safety assessment
Genetic toxicity in vitro
Description of key information
A number of in vitro studies (including Ames, in vitro cytogenetics and mammalian cell mutagenicity) and an in vivo mouse bonemarrow micronucleus assay showed no adverse effect observed (negative).
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (negative)
Genetic toxicity in vivo
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (negative)
Additional information
DEB mixed isomers was not genotoxic or mutagenic in any tests conducted, including the following: negative for bacterial and mammalian mutations, negative for chromosomal aberrations in CHO cells, and negative for induction of micronuclei in bone marrow erythrocytes from treated mice.
Justification for classification or non-classification
All test results were negative and therefore no classification for mutagenicity is required.
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