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EC number: 274-778-7 | CAS number: 70693-62-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to soil macroorganisms except arthropods
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to soil macroorganisms except arthropods: short-term
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2006-11-13 - 2007-01-10
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 207 (Earthworm, Acute Toxicity Tests)
- Deviations:
- no
- GLP compliance:
- yes
- Analytical monitoring:
- no
- Details on sampling:
- not indicated
- Vehicle:
- no
- Details on preparation and application of test substrate:
- not indicated
- Test organisms (species):
- Eisenia fetida
- Animal group:
- annelids
- Details on test organisms:
- TEST ORGANISM
- Common name: Earthworm (Eisenia foetida)
- Source: Vickers Farms, Orlando, Florida
- Age at test initiation: > 2 months, < 12 months
- Weight at test initiation: 300 – 600 mg
ACCLIMATION
- Acclimation period: 48 h
- Acclimation conditions: 18 to 22 °C - Study type:
- laboratory study
- Substrate type:
- artificial soil
- Limit test:
- no
- Total exposure duration:
- 14 d
- Post exposure observation period:
- not indicated
- Test temperature:
- 20°C±2°C
- pH:
- 5.9 – 6.3
- Moisture:
- 30 - 35%
- Details on test conditions:
- TEST SYSTEM
- Test container (material, size): gass jars of approx. 1.8 L volume
- Amount of soil or substrate: 0.75 kg/container
- No. of organisms per container: 10
- No. of replicates per concentration: 4
SOURCE AND PROPERTIES OF SUBSTRATE
- Composition of artificial substrate: 10% sphagnum, 20% kaolin clay (kaolinite content above 30%), 70% industrial sand (> 50% of the particles between 50 and 200 µm), Calcium carbonate
OTHER TEST CONDITIONS
- Photoperiod: continuous
- Light intensity: 401 – 541 lux
EFFECT PARAMETERS MEASURED: Mortality, biomass
Earthworms were assessed for mortality and behavioural effects after 7 and 14 days of exposure and earthworm body weights were assessed at day 0 and day 14.
VEHICLE CONTROL PERFORMED: no
TEST CONCENTRATIONS
- Range finding study:
- Test concentrations: 0 (control), 0.10, 1.0, 10, 100 and 1000 mg/kg KMPS triple salt/kg dry soil
- Results used to determine the conditions for the definitive study: After seven days of incubation, there was no mortality in the control through the highest treatment level. - Nominal and measured concentrations:
- Nominal levels of test concentrations: 65, 130, 250, 500, 1000 mg KMPS/mg dry soil
- Reference substance (positive control):
- yes
- Remarks:
- 2-Chloroacetamide
- Duration:
- 14 d
- Dose descriptor:
- LC0
- Effect conc.:
- 1 000 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Key result
- Duration:
- 14 d
- Dose descriptor:
- LC50
- Effect conc.:
- > 1 000 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Details on results:
- Details are given under "Remarks on results including tables and figures"
- Results with reference substance (positive control):
- 14-d LC50 > 1000 mg/kg dry soil
- Reported statistics and error estimates:
- No LC50 value could be calculated due to lack of mortality.
- Validity criteria fulfilled:
- yes
- Remarks:
- (Mortality of control animals < 10% )
- Conclusions:
- The study and the conclusions which are drawn from it fulfill the quality criteria (validity, reliability, repeatability). The study was performed according to OECD guideline 207. Control mortality was <10%. The validity criterion was met. The LC50 for earthworms was determined to be > 1000 mg/kg soil.
- Executive summary:
Materials and methods
The acute toxicity of KMPS triple salt to Eisenia foetida was determined in a dose-response 14-day test according to the OECD guideline 207.
Results and discussion
After 14 days of exposure to treated artificial soil the LC50 for earthworms was determined to be >1000 mg KMPS triple salt/mg soil. No effects on biomass or behaviour were evident.
LC0 = 1000 mg/kg soil
LC50 > 1000 mg/kg soil
Reference
Effects on biomass and mortality
Test item concentration (mg/kg soil) | Mean weight change per treatment (mg) | % weight change | Mortality (%) |
Control | -682 | -15 | 0 |
65 | -549 | -14 | 0 |
130 | -614 | -14 | 0 |
250 | -563 | -13 | 0 |
500 | -618 | -14 | 0 |
1000 | -597 | -14 | 0 |
Effect data
- | 14 d [mg/kg soil] | 95 % c.l. |
LC0 | 1000 | - |
LC50 | >1000 | - |
LC100 | not applicable | - |
based on nominal concentrations
Description of key information
The toxicity to soil macroorganisms of the test item was tested in an acute toxicity test to earthworm. The test was carried out in accordance with the OECD Guideline 207 (Earthworm, Acute Toxicity Tests).
Key value for chemical safety assessment
- Short-term EC50 or LC50 for soil macroorganisms:
- 1 000 mg/kg soil dw
Additional information
Shot-term toxicity to invertebrates
The acute toxicity of KMPS triple salt to Eisenia foetida was determined in a dose-response 14-day test according to the OECD guideline 207. After 14 days of exposure to treated artificial soil the LC50 for earthworms was determined to be >1000 mg KMPS triple salt/mg soil. No effects on biomass or behaviour were evident.
LC0 = 1000 mg/kg soil
LC50 > 1000 mg/kg soil
Long term toxicity to invertebrates
In accordance to section 9.4.4 of Annex X, long-term toxicity to invertebrates, does not need to be conducted if direct and indirect exposure of the soil compartment is unlikely. An acute toxicity test in Eisenia fetida was done with KMPS triple salt. Up to a test concentration of 1000 mg/L no toxic effect could be observed (LC50 > 1000 mg KMPS triple salt/ L). This result shows that KMPS triple salt has a very low acute toxicity to earthworms (IUCLID section 6.3.1). As there are no other indications of concern for the terrestrial compartment, further long-term testing is considered to be scientifically not justified.
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