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Toxicological information

Repeated dose toxicity: dermal

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Administrative data

Endpoint:
repeated dose toxicity: dermal
Data waiving:
other justification
Justification for data waiving:
other:

Data source

Materials and methods

Results and discussion

Target system / organ toxicity

Critical effects observed:
not specified

Applicant's summary and conclusion

Conclusions:
Chromium (VI) trioxide is corrosive to skin, therefore studies of repeated dose toxicity using dermal exposure are not justified for scientific reasons and on animal welfare grounds. Occupational exposure is primarily via inhalation; a repeated dose inhalation study is available.