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EC number: 204-463-1 | CAS number: 121-30-2
Biodegradation in water and sediment: simulation tests
Administrative data
- Endpoint:
- biodegradation in water and sediment: simulation tests
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Migrated phrase: estimated by calculation
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- other: Prediction model
- Title:
- Bio-degradation in water and sediment by EPI (Estimation Programs Interface) Suite
- Author:
- Sustainability Support Service (Europe) AB - estimated
- Year:
- 2 011
- Bibliographic source:
- Estimation Programs Interface Suite™ United States Environmental Protection Agency, Washington, DC, USA. version 4.1
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: Modeling database
- Principles of method if other than guideline:
- Fugacity Model by EPI Suite estimation database
- GLP compliance:
- no
Test material
- Reference substance name:
- 4-amino-6-chlorobenzene-1,3-disulphonamide
- EC Number:
- 204-463-1
- EC Name:
- 4-amino-6-chlorobenzene-1,3-disulphonamide
- Cas Number:
- 121-30-2
- Molecular formula:
- C6H8ClN3O4S2
- IUPAC Name:
- 4-amino-6-chlorobenzene-1,3-disulfonamide
- Details on test material:
- - Name of test material: 4-amino-6-chlorobenzene-1,3-disulphonamide
- Molecular formula: C6H8ClN3O4S2
- Molecular weight: 285.73
- Substance type: Organic
- Physical state: Solid
Constituent 1
- Radiolabelling:
- not specified
Study design
- Oxygen conditions:
- other: estimation
- Inoculum or test system:
- not specified
- Parameter followed for biodegradation estimation:
- test mat. analysis
Results and discussion
Mean total recoveryopen allclose all
- Compartment:
- other: water, material (mass) balance
- % Recovery:
- 33.9
- Compartment:
- other: sediment, material (mass) balance
- % Recovery:
- 0.089
% Degradationopen allclose all
- % Degr.:
- 50
- Parameter:
- other: Half life
- Sampling time:
- 60 d
- Remarks on result:
- other: 50% degradation in water
- % Degr.:
- 50
- Parameter:
- other: Half Life
- Sampling time:
- 541.66 d
- Remarks on result:
- other: 50% degradation in sediment.
Half-life of parent compound / 50% disappearance time (DT50)open allclose all
- Compartment:
- water
- DT50:
- 60 d
- Type:
- other: Estimated data
- Remarks on result:
- other: 50% degradation in water
- Compartment:
- sediment
- DT50:
- 541.66 d
- Type:
- other: Estimated data
- Remarks on result:
- other: 50% degradation in sediment.
- Transformation products:
- not specified
- Evaporation of parent compound:
- not specified
- Volatile metabolites:
- not specified
- Residues:
- not specified
Applicant's summary and conclusion
- Conclusions:
- 4-amino-6-chlorobenzene-1,3-disulphonamide is 50% biodegradable in water in 60 days (half-life) while in sediment it is 50% biodegradable in 541.66 days (half-life) indicating that it is persistent ( not readily biodegradable) in both water and sediment.
- Executive summary:
Mass Amount
(percent)
Half-Life
(hr)
Emissions
(kg/hr)
Water
33.9
1.44e+003
1000
Sediment
0.0887
1.3e+004
0
Fugacity
(atm)
Reaction
(kg/hr)
Advection
(kg/hr)
Reaction
(percent)
Advection
(percent)
Water
2.33e-019
740
1.54e+003
24.7
51.3
Sediment
2.29e-019
0.215
0.0806
0.00718
0.00269
Persistence Time: 1.51e+003 hr
Reaction Time: 3.11e+003 hr
Advection Time: 2.95e+003 hr
Percent Reacted: 48.7
Percent Advected: 51.3
Half-Lives (hr), (based upon Biowin (Ultimate) and Aopwin):
Air: 74.16
Water: 1440
Soil: 2880
Sediment: 1.296e+004
Biowin estimate: 2.226 (months )
Advection Times (hr):
Air: 100
Water: 1000
Sediment: 5e+004
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