Registration Dossier
Registration Dossier
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EC number: 204-463-1 | CAS number: 121-30-2
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Migrated phrase: estimated by calculation
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- other: Prediction model
- Title:
- Biodegradation in water by EPI (Estimation Programs Interface) Suite
- Author:
- Sustainability Support Service (Europe) AB - estimated
- Year:
- 2 011
- Bibliographic source:
- Estimation Programs Interface Suite™ United States Environmental Protection Agency, Washington, DC, USA. version 4.1
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: Modeling database
- Principles of method if other than guideline:
- BIOWIN (v4.10) Program by EPI Suite estimation database.
- GLP compliance:
- no
Test material
- Reference substance name:
- 4-amino-6-chlorobenzene-1,3-disulphonamide
- EC Number:
- 204-463-1
- EC Name:
- 4-amino-6-chlorobenzene-1,3-disulphonamide
- Cas Number:
- 121-30-2
- Molecular formula:
- C6H8ClN3O4S2
- IUPAC Name:
- 4-amino-6-chlorobenzene-1,3-disulfonamide
- Details on test material:
- - Name of test material: 4-amino-6-chlorobenzene-1,3-disulphonamide
- Molecular formula: C6H8ClN3O4S2
- Molecular weight: 285.73
- Substance type: Organic
- Physical state: Solid
Constituent 1
Study design
- Oxygen conditions:
- other: estimation
- Inoculum or test system:
- not specified
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- test mat. analysis
Results and discussion
% Degradationopen allclose all
- Parameter:
- % degradation (test mat. analysis)
- Value:
- 0.195
- Remarks on result:
- other: Biowin1 (Linear Model Prediction)
- Parameter:
- % degradation (test mat. analysis)
- Value:
- 0.007
- Remarks on result:
- other: Biowin2 (Non-Linear Model Prediction)
Applicant's summary and conclusion
- Interpretation of results:
- other: Does Not Biodegrade Fast
- Conclusions:
- According to Biowin1 (Linear Model Prediction) and Biowin2 (Non-Linear Model Prediction) the biodegaradtion value of
4-amino-6-chlorobenzene-1,3-disulphonamide estimated to be 0.1954 and 0.0069 respectively indicating that 4-amino-6-chlorobenzene-1,3-disulphonamide is not readily biodegradable. - Executive summary:
------+-----+--------------------------------------------+---------+---------
TYPE | NUM | Biowin1 FRAGMENT DESCRIPTION | COEFF | VALUE
------+-----+--------------------------------------------+---------+---------
Frag | 1 | Aromatic chloride [-CL] | -0.1824 | -0.1824
Frag | 1 | Aromatic amine [-NH2 or -NH-] | -0.2338 | -0.2338
MolWt| * | Molecular Weight Parameter | | -0.1360
Const| * | Equation Constant | | 0.7475
============+============================================+=========+=========
RESULT | Biowin1 (Linear Biodeg Probability) | | 0.1954
============+============================================+=========+=========
------+-----+--------------------------------------------+---------+---------
TYPE | NUM | Biowin2 FRAGMENT DESCRIPTION | COEFF | VALUE
------+-----+--------------------------------------------+---------+---------
Frag | 1 | Aromatic chloride [-CL] | -2.0155 | -2.0155
Frag | 1 | Aromatic amine [-NH2 or -NH-] | -1.9070 | -1.9070
MolWt| * | Molecular Weight Parameter | | -4.0572
============+============================================+=========+=========
RESULT | Biowin2 (Non-Linear Biodeg Probability) | | 0.0069
============+============================================+=========+=========
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