Registration Dossier
Registration Dossier
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EC number: 201-152-2 | CAS number: 78-87-5
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2003
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- publication
- Title:
- OECD SIDS 1,2-DICHLOROPROPANE
- Author:
- OECD SIDS
- Year:
- 2 003
- Bibliographic source:
- UNEP PUBLICATIONS
- Report date:
- 2003
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Method not available
- GLP compliance:
- no
- Test type:
- acute toxic class method
Test material
- Reference substance name:
- 1,2-dichloropropane
- EC Number:
- 201-152-2
- EC Name:
- 1,2-dichloropropane
- Cas Number:
- 78-87-5
- Molecular formula:
- C3H6Cl2
- IUPAC Name:
- 1,2-dichloropropane
- Details on test material:
- Name. 1,2-dichloropropane
Constituent 1
Test animals
- Species:
- rat
- Strain:
- other: Carforth-Wistar
- Sex:
- male/female
Administration / exposure
- Route of administration:
- oral: unspecified
- Vehicle:
- unchanged (no vehicle)
Results and discussion
Effect levels
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- 2 200 mg/kg bw
Any other information on results incl. tables
Acute oral LD50 = 1.9 +/- 0.2 ml/kg (mean and SD) This is equivalent to 2200 mg/kg bw, based on a density of 1.155 g/ml [Source: MacKay et al (1993) Illustrated Handbook of Physical-Chemical Properties and Environmental Fate for Organic Chemicals, Vol III, p479]
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- LD50 = 2200 mg/kg bw
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