Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Exposure related observations in humans: other data

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Administrative data

Endpoint:
exposure-related observations in humans: other data
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: study data do not give sufficient experimental details

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1958

Materials and methods

Type of study / information:
skin irritation in human volunteers
Endpoint addressed:
skin irritation / corrosion
Principles of method if other than guideline:
other: patch-test
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
6,6'-di-tert-butyl-2,2'-methylenedi-p-cresol
EC Number:
204-327-1
EC Name:
6,6'-di-tert-butyl-2,2'-methylenedi-p-cresol
Cas Number:
119-47-1
Molecular formula:
C23H32O2
IUPAC Name:
2-tert-butyl-6-[(3-tert-butyl-2-hydroxy-5-methylphenyl)methyl]-4-methylphenol
Details on test material:
no data

Method

Details on study design:
no data

Results and discussion

Results:
No irritating effects were observed in 0/6 volunteers

Any other information on results incl. tables

No irritating effects were observed at the end of the treatment.

Applicant's summary and conclusion