Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 208-307-3 | CAS number: 521-18-6
Water solubility
Administrative data
Link to relevant study record(s)
Description of key information
GLP study according to EU Testing Guideline A.6 (column elution method).
Analytical Development Physical Chemistry, Schering AG Berlin. Study report No. A04561 (ADP 2001_113), dated 2001-07-12.
Result: S approx. 3.5 mg/L at 20°C (below LOQ)
Key value for chemical safety assessment
Additional information
The water solubility of androstanolone at 20°C was determined using the column elution method, which is based on the elution of the test substance with water from a micro column which is filled with an inert support material (quartz), previously charged with the test substance. The water is continuously circulated through the column until saturation equilibrium is reached as indicated by a practically constant concentration of androstanolone. The concentration was monitored by HPLC analysis in samples drawn during the course of equilibration time.
The water solubility at 20°C was found between the limit of detection (2.3 mg/L) and the limit of quantitation (8.4 mg/L) of the HPLC method to be approx. 3.5 mg/L.
Androstanolone can be considered as insoluble in water in accordance with the descriptive term of EP 3rd ed. and USP 24.
The pH value of the saturated water solutions was determined to be 5.4.Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
