(8α,9R,8'''α,9'''R)-1,1'-[(2,3,5,6-tetrafluoro-1,4-phenylene)bis(methylene)]bis(6'-methoxycinchonan-1-ium-9-ol) dibromide

Melting point / freezing point

Link to relevant study record(s)

Reference

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 102 (Melting point / Melting Range)

Version / remarks:

1995

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

differential scanning calorimetry

Key result

Decomposition:

yes

Decomp. temp.:

> 166 °C

The substance was determined to decompose, without any evidence of melting, from approximately 166 °C (439 K). Decomposition was observed in both air and nitrogen atmospheres.

Conclusions:

A melting temperature could not be determined due to thermal decomposition of the substance.

Executive summary:

The melting temperature of the substance was determined under GLP in a study conducted according to OECD TG 102, by differential scanning calorimetry. Aliquots of about 5 to 6 mg of the test substance were placed in aluminium crucibles with manually pierced lids. Two determinations were made in an air atmosphere and two determinations in a nitrogen atmosphere under atmospheric pressure. On thermal analysis, no evidence of a phase transition (melting) was observed in any determination. All thermogram profiles showed only a single exothermic thermal event, attributed to decomposition of the test substance, which started from approximately 166 °C.

Description of key information

A melting temperature could not be determined due to thermal decomposition of the substance, starting from about 166 °C.