Registration Dossier
Registration Dossier
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EC number: 233-054-0 | CAS number: 10026-04-7
Eye irritation
Administrative data
- Endpoint:
- eye irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- No data
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- documentation insufficient for assessment
Data source
Reference
- Title:
- Unnamed
- Year:
- 1 978
- Report date:
- 1978
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- GLP compliance:
- no
Test material
- Reference substance name:
- Silicon tetrachloride
- EC Number:
- 233-054-0
- EC Name:
- Silicon tetrachloride
- Cas Number:
- 10026-04-7
- Molecular formula:
- Cl4Si
- IUPAC Name:
- tetrachlorosilane
Constituent 1
Test animals / tissue source
- Species:
- rabbit
- Strain:
- not specified
Test system
- Vehicle:
- unchanged (no vehicle)
- Amount / concentration applied:
- 0.1 mL/undiluted
- Duration of treatment / exposure:
- 24 hour(s)
Results and discussion
In vivo
Results
- Irritation parameter:
- other: Overall irritation score
- Remarks on result:
- other: Immediate observations: corrosive to conjunctivae; Following 10 minutes exposure: cornea opalescent; Following 24 hours: corrosive
Applicant's summary and conclusion
- Interpretation of results:
- study cannot be used for classification
- Conclusions:
- In a very limited summary of an in vivo eye irritation study, not conducted according to any OECD Test Guideline and GLP, silicon tetrachloride was concluded to be corrosive to the eye of rabbits.
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