1-[(2-chloro-4-nitrophenyl)azo]-2-naphthol

Bioaccumulation: aquatic / sediment

Administrative data

Endpoint:

bioaccumulation in aquatic species: fish

Type of information:

migrated information: read-across based on grouping of substances (category approach)

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Read across to Pigment Red 3– this is another substance in the Monoazo Red consortium which is a structural analogue

Data source

Reference

Reference Type:

publication

Title:

Biodegradation and Bioconcentration of existing Chemical substances

Author:

Unknown

Bibliographic source:

National Insitute of Technology and Evaluation

Report date:

1998

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

OECD Guideline 305 C (Bioaccumulation: Test for the Degree of Bioconcentration in Fish)

GLP compliance:

not specified

Test material

Test material information

Constituent 1

Reference substance name:

1-(4-methyl-2-nitrophenylazo)-2-naphthol

EC Number:

219-372-2

EC Name:

1-(4-methyl-2-nitrophenylazo)-2-naphthol

Cas Number:

2425-85-6

Molecular formula:

C17H13N3O3

IUPAC Name:

1-[(4-methyl-2-nitrophenyl)diazenyl]-2-naphthol

Details on test material:

Purity: 96.6%

Test organisms

Test organisms (species):

Cyprinus carpio

Study design

Total exposure / uptake duration:

6 wk

Test conditions

Nominal and measured concentrations:

Nominal concentrations: 0.1 and 1 mg/L

Results and discussion

Bioaccumulation factor

Bioaccumulation factor 1

Type:

BCF

Value:

< 2.9 L/kg

Remarks on result:

other: Conc.in environment / dose:0.1mg/L

Bioaccumulation factor 2

Type:

BCF

Value:

0.3 - < 2.7 L/kg

Remarks on result:

other: Conc.in environment / dose:1 mg/L

Applicant's summary and conclusion

Validity criteria fulfilled:

yes

Conclusions:

Low bioaccumulatuion potential