Registration Dossier

Toxicological information

Carcinogenicity

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Description of key information

There is no available study on the chronic toxicity and carcinogenicity of tert-dodecanethiol (TDM). However, results from subchronic studies indicate that TDM does not cause any significant systemic toxicity resulting from prolonged exposure. The consistently negative results from the series of in vitro genotoxicity tests assessing gene mutation, DNA perturbation and chromosomal damage do not suggest any cause for concern with respect to carcinogenicity.

Key value for chemical safety assessment

Carcinogenicity: via oral route

Endpoint conclusion
Endpoint conclusion:
no study available

Carcinogenicity: via inhalation route

Endpoint conclusion
Endpoint conclusion:
no study available

Carcinogenicity: via dermal route

Endpoint conclusion
Endpoint conclusion:
no study available

Additional information

Justification for classification or non-classification