Registration Dossier
Registration Dossier
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EC number: 203-744-6 | CAS number: 110-18-9
PBT assessment
Administrative data
PBT assessment: overall result
- Name:
- TMEDA
- Type of composition:
- boundary composition of the substance
- State / form:
- liquid
- Reference substance:
- TMEDA
- Name:
- TMEDA
- Type of composition:
- legal entity composition of the substance
- State / form:
- liquid
- Reference substance:
- TMEDA
- PBT status:
- the substance is not PBT / vPvB
- Justification:
Based on available data, it is concluded that TMEDA does not meet the criteria to be considered either PBT or vPvB.
Simulation studies investigating the degradability of TMEDA are not available, however a ready biodegradability study according to OECD guideline 301B is available which concluded that TMEDA is not readily biodegradable. Consequently, it is concluded that TMEDA should be considered to be potentially persistent (P) or very persistent (vP).
The n-octanol/water partition coefficient (log Pow) of TMEDA was determined to be -0.13 according an OECD guideline 107 and EC method A.8 (440/2008/EEC) experimental study. Given this low log Kow value (i.e. < 3), it is concluded that TMEDA has no potential for bioaccumulation and as such is concluded to be not bioaccumulative (B) or very bioaccumulative (vB).
Experimental data investigating the ecotoxicity of TMEDA are available from a short-term fish toxicity study, a short-term Daphnia toxicity study and an algal growth inhibition study. Long-term ecotoxicity data are not available for fish or aquatic invertebrates. The algal growth inhibition study showed the most conservative toxicity data from these studies, having resulted in a 72-h ErC50 value of 20.5 mg/L and a 72-h NOEC of 0.954 mg/L. As such, it is concluded that TMEDA is not considered to be toxic (T) as the basis of ecotoxicity.
Referenceopen allclose all
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