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EC number: 263-158-1 | CAS number: 61790-67-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 24 November 2015 to 6 September 2016
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- effusion method: Knudsen cell
- Key result
- Temp.:
- 20 °C
- Vapour pressure:
- 0.001 Pa
- Temp.:
- 25 °C
- Vapour pressure:
- 0.001 Pa
- Conclusions:
- Under the conditions of the study, the vapour pressure of the test material was determined to be 0.00082 Pa at 20 °C and 0.00119 Pa at 25 °C.
- Executive summary:
The vapour pressure of the test material was investigated in a study which was performed under GLP conditions and in accordance with the standardised guideline OECD 104.
The experimental procedure followed the Knudsen cell effusion method. Preliminary experiments were performed to assess the potential effect of more volatile components in the test material. The data suggested that there were a proportion of volatile
components which slowly diminish over prolonged testing. For substance that contain volatile components, it has been previously proven that a new samples of test substance should be taken to be used for each temperature to gives an accurate estimation of the vapour pressure. A total of 14 aliquots (7 to 9 mg) of test material were weighed into 40 µL aluminium crucibles. Lids with an orifice of a nominal 1.0 mm diameter (accurately measured), were cold welded onto each crucible and the crucibles weighed. The test temperatures used were: 15, 20 (duplicated) 63, 74, 85 and 97 °C. Two crucibles were used for each temperature. The time under vacuum was 15 to 50 minutes, when the crucible was re-weighed and a sample taken for IR analysis. A separate crucible was prepared in the same manner, except a non-perforated lid was cold welded onto it. This crucible remained in the apparatus for the all the tests to act as a control. The test was started at 15 °C, but the vapour pressure was too low to be measured experimentally at this temperature so only data at 20 °C, 63 °C, 74 °C, 85 °C and 97 °C was used for the calculation of the vapour pressure.
Under the conditions of the study, the vapour pressure of the test material was determined to be 0.00082 Pa at 20 °C and 0.00119 Pa at 25 °C.
Reference
The test was started at 15 °C, but the vapour pressure was too low to be measured experimentally at this temperature so only data at 20 °C, 63 °C, 74 °C, 85 °C and 97 °C was used for the calculation of the vapour pressure.
The vapour pressure of the test material was 0.00082 Pa at 20 °C and 0.00119 Pa at 25 °C.
Small peaks on the IR spectrum at 3342 and 3313 cm^-1 were attributable to amine groups and test material. These peaks are present in about the same proportion in the control and untested sample, confirming thermal stability over the different temperatures. These peaks gradually diminished with the higher test temperature, until at 97 °C they were almost completely absent. The remainder of the spectra remained unchanged. This would suggest the removal of triethanolamine and the active ingredient remained stable.
Table 1. Vapour PressureMeasurements
Run Number |
Temp (°C) |
Crucible Weight (mg) |
1/T (K-1) |
Vapour Pressure (Pa) |
Ln (VP) |
|||
Test 1 |
Test 2 |
Test 1 |
Test 2 |
Test 1 |
Test 2 |
|||
2 |
20.0 |
56.279 |
55.681 |
3.41E-03 |
1.09E-03 |
1.07E-03 |
-6.82 |
-6.84 |
56.273 |
55.675 |
|||||||
3 |
20.0 |
56.459 |
56.136 |
3.41E-03 |
6.42E-04 |
4.95E-04 |
-7.35 |
-7.61 |
56.450 |
56.129 |
|||||||
4 |
63.0 |
56.352 |
57.026 |
2.97E-03 |
1.73E-02 |
1.78E-02 |
-4.06 |
-4.03 |
56.280 |
56.956 |
|||||||
5 |
74.0 |
55.851 |
56.692 |
2.88E-03 |
3.38E-02 |
2.30E-02 |
-3.39 |
-3.77 |
55.719 |
56.603 |
|||||||
6 |
85.0 |
55.260 |
56.493 |
2.79E-03 |
4.05E-02 |
4.62E-02 |
-3.21 |
-3.07 |
55.106 |
56.316 |
|||||||
7 |
97.0 |
57.207 |
55.993 |
2.70E-03 |
8.46E-03 |
6.24E-02 |
-2.47 |
-2.77 |
56.891 |
55.759 |
Table 2: Extrapolated Vapour Pressure (VP) Results
Slope |
Intercept |
Correlation |
Vapour Pressure (Pa) |
|
At 20 °C |
At 25 °C |
|||
-6513.1 |
15.11 |
-0.9909 |
0.00082 |
0.00119 |
Note the results for Run 1 are not recorded here, because the weight loss was too low for a vapour pressure to be recorded.
Description of key information
Under the conditions of the study, the vapour pressure of the test material was determined to be 0.00082 Pa at °C and 0.00119 Pa at 25 °C.
Key value for chemical safety assessment
- Vapour pressure:
- 0.001 Pa
- at the temperature of:
- 20 °C
Additional information
The vapour pressure of the test material was investigated in a study which was performed under GLP conditions and in accordance with the standardised guideline OECD 104. The study was assigned a reliability score of 1 in accordance with the criteria for assessing data quality set forth by Klimisch et al. (1997).
The experimental procedure followed the Knudsen cell effusion method. Preliminary experiments were performed to assess the potential effect of more volatile components in the test material. The data suggested that there were a proportion of volatile
components which slowly diminish over prolonged testing. For substance that contain volatile components, it has been previously proven that a new samples of test substance should be taken to be used for each temperature to gives an accurate estimation of the vapour pressure. A total of 14 aliquots (7 to 9 mg) of test material were weighed into 40 µL aluminium crucibles. Lids with an orifice of a nominal 1.0 mm diameter (accurately measured), were cold welded onto each crucible and the crucibles weighed. The test temperatures used were: 15, 20 (duplicated) 63, 74, 85 and 97 °C. Two crucibles were used for each temperature. The time under vacuum was 15 to 50 minutes, when the crucible was re-weighed and a sample taken for IR analysis. A separate crucible was prepared in the same manner, except a non-perforated lid was cold welded onto it. This crucible remained in the apparatus for the all the tests to act as a control. The test was started at 15 °C, but the vapour pressure was too low to be measured experimentally at this temperature so only data at 20 °C, 63 °C, 74 °C, 85 °C and 97 °C was used for the calculation of the vapour pressure. The vapour pressure of the test material was 0.00082 Pa at 20 °C and 0.00119 Pa at 25 °C.
Under the conditions of the study, the vapour pressure of the test material was determined to be 0.00082 Pa at 20 °C and 0.00119 Pa at 25 °C.
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