Brief Profile
Brief Profile
Data platform availability banner - brief profile
Please be aware that the REACH registration parts of this Brief Profile are no longer maintained; they remain frozen as of 19th May 2023. All other data parts (substance identity, C&L, key regulatory lists etc. are up to date).
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Brief Profile
The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.
Ethanol
Brief Profile - Last updated: 14/10/2024 Print
-
Sub. description
Substance description
Substance description
The ’Substance description’ gives an overview of the main substance identifiers, substance classification, on-going regulatory activities, main uses of the substance and which registrants manufacture and/or import the substance. By summarising this information in a single page, ECHA aims to make this information accessible in a user-friendly way in line with the Agency’s goals and standards.
Data from all dossiers registered and the Classifications and Labelling Inventory (C&L) for the same substance are used to generate the Brief Profile. The information provided in the free-text fields is not published in the Brief Profiles.
The Brief Profile is automatically generated; information requirements under different legislative frameworks may, therefore, not be up-to-date or complete. For accuracy reasons, substance manufacturers and importers are responsible for consulting official sources. This Brief Profile is covered by the ECHA Legal Disclaimer.
Generating the Brief Profiles
The Brief Profile summarises the non-confidential data on substances as it is held in the databases of the European Chemical Agency (ECHA), including data provided by third parties. The Brief Profile is produced based on data in ECHA’s databases and maintained by the Agency, and therefore the Brief Profile as a dissemination tool falls under ECHA’s responsibility.
Due to the quantity of information and the number of chemicals, the Brief Profile is automatically generated based on the information available and is not manually verified. For sections such as substance use, chemical properties and the classification and labelling of substances, the quantity and quality of the information is the responsibility of manufacturers and importers. While the Agency tries to aggregate the information on chemicals in the best possible way, ECHA cannot check whether all the information provided by industry is free of errors.
Updates
Brief Profiles are updated regularly and new information is added when available. Since the source data can be updated at any time while the Brief Profiles are updated at intervals, a slight delay in the publication of information may occur.
The date of the last update corresponds to the publication date of the Brief Profile and not necessarily to the date in which the update occurred in the source data (registered dossiers, the C&L Inventory or a regulatory process).
Furthermore, updates in the source data may not always result in an update of the Brief Profile. For example, an update in a section of a dossier that is not displayed in the Brief Profile will not result in an update of the Brief Profile.
Dealing with Brief Profile errors
If you have any comments or suggestions, please contact ECHA using our contact form.
-
Sci. properties
Scientific properties
Scientific properties
The ‘Scientific properties’ section gives an overview of summarised scientific data from registered dossiers. By summarising the endpoint study data, ECHA aims to make this information accessible in a user-friendly way in line with the Agency’s goals and standards.
All the source data on which the summaries on this page are based, is provided by industry and stored in the ECHA databases. Data from all dossiers registered for the same substance is used in the summarisation and aggregation process, as it is presumed that all data submitted by the registrants is relevant for the substance being registered. If the test material used is different from the substance being registered an indication will be provided. Please note that the information provided in the free-text fields is not published in the brief profiles.
Information in the ‘Scientific properties’ section is structured by substance properties, further broken down into endpoints. Each endpoint includes three information blocks:
- Study results – this information is collected from those endpoint study records provided by registrants of REACH dossiers which are flagged as Key or Weight of Evidence studies, and which have an indicated reliability (i.e. Klimisch score) of 1 or 2. Other types of studies are not processed for the Brief Profiles.
- Type of study provided – Provides an overview of the type of study records behind the presented results and data–waving justifications (e.g. key experimental study, Supporting QSAR study, etc.)
- Summary data – this information is collected from the endpoint summaries provided by registrants of REACH dossiers.
Note: Information presented in this section is generated as part of an automatic process, i.e. there is no manual verification or assessment of the correctness of the data. If no data is available in the registered substance dossiers, this will be indicated by a notification stating ‘Data not provided by the registrant’.
Summarisation and prioritisation of data
There are four methods to aggregate and summarise data, depending on the available data and endpoint. An icon is displayed to indicate the type of aggregation and summarisation performed:
- [R] Range of values – Range of results values (min-max) and range values of experimental condition(s) (min-max).
- [C] Concatenate distinct – Value types are ranked from most to least commonly provided, with a % attributed based on the count of total values provided.
- [M/C] Most conservative - Most conservative of all the data values provided, applying a precautionary principle (e.g. the lowest threshold or most hazardous statement)
- [P] Prioritisation – The result to be displayed is based on a set of criteria. For example, for endpoints related to (eco)toxicology four main types of criteria exist to prioritise the display of information: test species, dose descriptor, duration and measurement units. For Toxicology endpoint summaries two other criteria can be applied: Test type (Chronic, subchronic and subacute) and endpoint conclusion.
The precise data summarisation methods are specified per endpoint summary/study.
When more than one numerical result is available per endpoint the count is displayed between square brackets.
Units and data are normalised when possible and therefore the unit of measure/order of magnitude in the Brief Profile data may not correspond exactly to the one in the registered dossier. For temperature for example, data is standardised and displayed in Celsius (°C). For other data an order of magnitude logic might apply; e.g. 1 000 g will be displayed as 1 kg.
Processed studies and data-waiving
Due to the number of the substances and the associated information, substance data is processed and aggregated in an automatic process. Therefore, data has to fit the format and aggregation logic that is used for the Brief Profile.
Though the Agency aims to include as many studies as possible in the Brief Profile endpoint study results/summaries, those studies which do not fit the format or miss crucial information (such as measurement conditions) cannot be processed and therefore will not be included on this page. These study results can however be consulted when opening the source data.
The number of studies provided is indicated by ‘[x] studies submitted’, while the actual number of studies processed for the endpoint is indicated by ‘[x] studies processed’.
Data waiving
If only waived data is available for the substance, following justifications for data-waiving can be displayed in the Brief Profile:
- Study technically not feasible
- Study scientifically unjustified
- Exposure considerations
- Other justification
Excluded endpoints
Some endpoints are not included in the Brief Profile due to the use of free text and/or complex field(s) in the reporting of information, which cannot be easily summarised by an automatic algorithm. Please see the registered dossiers for substance information for the following endpoints:
- Particle size distribution
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- Additional physical-chemical information
- Mode of degradation in actual use
- Other distribution data
- Environmental data (monitoring data/field studies)
- Additional information on environmental fate and behaviour
- Toxicity to other aquatic organisms
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxicological information
- Skin irritation/corrosion (study results)
- Eye irritation (study results)
- Skin sensitisation (study results)
- Respiratory sensitisation (study results)
- Repeating dose toxicity oral/inhalation/dermal/other routes (study results)
- Toxicity to reproduction (study results)
- Developmental toxicity (study results)
- Toxicity to reproduction: other studies
- Specific investigations: other studies
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological information
Substance Description
Substance identity
The ’Substance identity’ section links substance identification information from all databases that are maintained by ECHA. The substance identifiers – if available and not claimed confidential – displayed in the ’Substance identity’ section of the Brief Profile are:
- EC name/number
- IUPAC name/number
- CAS number
- Index number
- Molecular formula
- Smiles
- InChI
In addition, information on the type of substance, origin, number and type of registered compositions and other places where the substance is listed are displayed in this section.
EC (European Community) name/number
The EC name and number are the official identifiers for substances within the European Union and can be found in the EC Inventory.
The EC Inventory is a combination of three independent European lists of substances from the previous EU chemicals regulatory frameworks (EINECS, ELINCS and the NLP-list). More information about the EC Inventory can be found here. If the substance has no EC number attributed, ECHA will attribute a list number. These numbers start with 6, 7, 8 or 9.
IUPAC name/number
An IUPAC name is based on the international standard chemical nomenclature set by the International Union of Pure and Applied Chemistry (IUPAC).
The IUPAC nomenclature is a systematic way of naming chemical substances, both organic and inorganic. In IUPAC nomenclature, prefixes, suffixes and infixes are used to describe the type and position of functional groups in the substance.
If more than one IUPAC name is available from REACH registered dossiers, all IUPAC names are displayed in ‘Other names’ section of the Brief Profile.
See the official IUPAC website for more information on the International Union of Pure and Applied Chemistry.
CAS (Chemical Abstract Service) registry number
The CAS number is the substance numerical identifier assigned by the Chemical Abstract Service, a division of the American Chemical Society, to substances registered in the CAS registry database. A substance may have more than one CAS number associated. In this case, the preferred CAS number is displayed first. More about CAS and the CAS registry can be found here.
Index number
The Index number is the identification code given to substances in Part 3 of Annex VI to the CLP Regulation ((EC) No 1272/2008). A distinct classification and labelling corresponds to each Index number.
The Index number for each substance is in the form of a digit sequence of the type ABC-RST-VW-Y. ABC corresponds to the atomic number of the most characteristic element or the most characteristic organic group in the molecule. RST is the consecutive number of the substance in the series ABC. VW denotes the form in which the substance is produced or placed on the market. Y is the check-digit calculated in accordance with the 10-digit ISBN method.
Molecular formula
The molecular formula identifies each type of element by its chemical symbol and identifies the number of atoms of each element found in one discrete molecule of the substance. If such information is available in ECHA’s database and is it not claimed confidential, the molecular formula and molecular structure will be displayed here.
SMILES
SMILES is the acronym for Simplified Molecular Input Line Entry Specification, a chemical notation system used to represent a molecular structure by a linear string of symbols.
With standard SMILES, the name of a molecule is synonymous with its structure: it indirectly shows a two dimensional picture of the molecular structure. Since a two dimensional chemical structure can be drawn in various ways, there are several correct SMILES notations for one molecule.
The basis of SMILES is the representation of a valence model of a molecule. SMILES notations are comprised of atoms (designated by elemental symbols), bonds, parentheses (used to show branching), and numbers (used for cyclic structures).
InChI
InChI is an abbreviated name for IUPAC International Chemical Identifier, a chemical identifier developed and supported by the InChI Trust.
InChIs consist of text strings comprising different layers and sublayers of information separated by slashes (/). Each InChI string starts with the InChI version number followed by the main layer. This main layer contains sublayers for the chemical formula, atom connections and hydrogen atoms. Depending on the structure of the molecule the main layer may be followed by additional layers e.g. for charge, stereo–chemical and/or isotopic information.
Molecular structure
Molecular structure displayed in this section is based on InChI annotation from IUCLID reference substances database and stored in the ECHA database. The structure is a computer generated visualisation of the molecular structure derived from the InChI character string.
Type of substance
Registrants can identify their substance as being a mono-constituent substance, multi-constituent substance, UVCB, polymer or specify another type. If more than one type of substance is registered, both types will be displayed.
Origin
Registrants can identify the origin of their substance as being:
- Element
- Inorganic
- Organic
- Organometallic
- Petroleum product
- Other
If more than one type of substance is registered, both types will be displayed.
Registered compositions (additives and impurities)
The total number of non-confidential registered compositions submitted in REACH dossiers are displayed here. If there are additives and impurities relevant for the substance classification, these are also indicated.
Within the context of REACH, impurities are unintended constituents present in a substance as manufactured. It may, for example, originate from the starting materials or be the result of secondary or incomplete reactions during the production process. While it is present in the final substance, it was not intentionally added. In most cases, impurities constitute less than 10% of the substance.
Additives are the constituents which have been intentionally added during the manufacturing process to stabilise the substance.
Substance listed
Provides information if the substance has been identified by one of the following previous EU chemicals regulatory frameworks:
- EINECS (European INventory of Existing Commercial chemical Substances) List
- ELINCS (European LIst of Notified Chemical Substances) List
- NLP (No-Longer Polymers) List
- EC / List name:
- IUPAC name: ethanol
- Substance names and other identifiers
- EC / List no.:
- 200-578-6
- CAS no.:
- 64-17-5
- Index number:
- 603-002-00-5
- Molecular formula:
- C2H6O
- SMILES:
- CCO
- InChI:
- InChI=1S/C2H6O/c1-2-3/h3H,2H2,1H3
- Type of substance:
- Mono constituent substance
- Origin:
- Organic
- Registered compositions:
- 111
- Of which contain:
- 43 impurities relevant for classification
- 7 additives relevant for classification
- Substance Listed:
- EINECS (European INventory of Existing Commercial chemical Substances) List
Hazard classification & labelling
The ‘Hazard classification and labelling’ section shows the hazards of a substance through a standardised system of statements and pictograms, as has been established under CLP (Classification Labelling and Packaging) Regulation. The CLP Regulation makes sure that the hazards presented by chemicals are clearly communicated to workers and consumers in the European Union. The CLP Regulation uses the UN Global Harmonised System (GHS) and European Union Specific Hazard Statements (EUH).
This section searches three sources for information (harmonised classification and labelling (CLH), REACH registrations and CLP notifications). The source of the information is mentioned in the introductory sentence of the hazard statement.
More information about classification and labelling can be found in the Regulations section of ECHA website.
Please note:
The purpose of the information provided under this section is to highlight in a readable format the substance hazardousness. It does not represent a new labelling, classification or hazard statement. Other relevant information includes the following:
- Substances may have impurities and additives that lead to different classifications. However, substance notifications in the Brief Profile are aggregated independently of the impurities and additives.
- Hazard statements were adapted to improve readability and may not correspond textually to the hazard statements codes description in the European Union Specific Hazard Statements (EUH) or UN Global Harmonised System (GHS).
To see the full list of notified classifications and have more information on impurities and additives relevant to classification, you can consult the C&L Inventory.
Harmonised classification and labelling (CLH)
The Hazard classification and labelling section uses the signal word, pictogram(s) and hazard statements of the substance under the harmonised classification and labelling (CLH) as its primary source of information. Substance classifications under CLH are agreed at the Community level. Harmonisation is based on the substance’s physical, toxicological and eco-toxicological hazard assessment.
It is possible that the harmonisation is introduced through an amendment to the CLP Regulation. In that case, the ATP (Adaptation to Technical Progress) number is displayed. More information on CLH can be found here.
If the substance is classified under more than one CLH entry (e.g. disodium tetraborate EC no. 215–540–4, is covered by three harmonisations – 005–011–00–4; 005–011–01–1; 005–011–02–9), CLH information cannot be displayed in the Brief Profile as the differences between the CLH classifications require manual verification. If a substance is classified under multiple CLHs, a link to the C&L Inventory is provided to allow users to view CLH information manually, instead of having the information automatically generated in the Brief Profile.
Classification and labelling under REACH
Additional information on classification and labelling (C&L) – if available – is derived from REACH registration dossiers submitted by industry. This information has not been reviewed or verified by ECHA, and may change without prior notice. REACH registration dossiers have greater data requirements (support studies) than notifications under CLP. When submitted by the lead of a joint submission, the classifications may also reveal agreement between companies.
Notifications under the Classification, Labelling and Packaging (CLP) Regulation
If additional information derived from classification and labelling (C&L) notifications to ECHA under the CLP Regulation exists, this will be displayed below the information derived from harmonised classification and labelling and REACH registrations. These notifications can be provided by manufacturers, importers and downstream users. ECHA maintains the C&L Inventory, but does not review or verify the accuracy of the information.
For readability purposes, only the pictograms, signal words and hazard statements referred to in more than 5% of the notifications under CLP are displayed.
Danger! According to the harmonised classification and labelling (CLP00) approved by the European Union, this substance is a highly flammable liquid and vapour.
Additionally, the classification provided by companies to ECHA in REACH registrations identifies that this substance causes damage to organs, is toxic if swallowed, may cause cancer, is toxic in contact with skin, is toxic if inhaled, causes serious eye damage and causes skin irritation.
Additionally, the classification provided by companies to ECHA in CLP notifications identifies that this substance causes serious eye irritation.
Breakdown of all 13836 C&L notifications submitted to ECHA
The chart displays the number of matching substance classifications (hazard class, categories and hazard statements) provided by manufacturers and importers under REACH and CLP notifications, as well as whether the substance is defined under harmonised classification and labelling (CLH).
The results of matching substance classifications are displayed in percentages of the total number of notifications. The bars indicate the number of matching classifications, i.e. the level of agreement, in substance classification between the REACH registrants (dark blue bar) and CLP notifiers (light blue bar), as well as between the notified classifications and the approved harmonised classification.
Harmonised classifications (√ - check mark)
- The (√- check mark)-icon indicates the classification is defined under harmonised classification and labelling (in accordance with the CLP Regulation) and made obligatory at Community level to ensure an adequate risk management throughout the European Community.
REACH & CLP classifications (bar)
- The dark blue bar illustrates the percentage of matching substance classifications provided by manufacturers and importers in a REACH registration dossier. Classifications under REACH have to be supported by data (support studies).
- The light blue bar illustrates the percentage of matching substance classifications provided by manufacturers and importers in CLP notifications.
Divergent classifications and impurities
The physical state and form of a substance can play a significant impact when the hazards of a substance are assessed. REACH and/or CLP notifiers may classify a substance differently based on different studies or the way they access the data.
For example, substance impurities can constitute a valid reason for a different classification of the substance. Different compositions or impurity profiles often lead to different classifications. If impurities and/or additives have been identified, an informative sentence is displayed below the graphic.
Different classifications can also be due to technical errors made during the notification process.
To have more information on impurities relevant to classification you can consult the C&L Inventory entry for the substance, or the disseminated registration dossier.
Harmonised Classification
REACH registration dossiers notifications
CLP notifications
At least one notifier has indicated that an impurity or an additive present in the substance impacts the notified classification.
Properties of concern
The ‘Properties of concern’ section shows ECHA-assigned graphical indicators for certain substance properties that are regarded as critical for human health and/or the environment based on the information provided to the Agency. The following properties have been highlighted as critical:
- C – This substance was identified as a carcinogenic (i.e. classified in Carcinogenicity categories 1A or 1B) in the EU harmonised classification and labelling and/or in a REACH registration dossier. More information about carcinogenicity here.
- M – This substance was identified as Mutagenic (i.e. classified in Mutagenicity categories 1A or 1B) in the EU harmonised classification and labelling and/or by a REACH registration dossier. More information about mutagenicity here.
- R – This substance was identified as toxic to reproduction (i.e. classified in reproductive toxicity categories 1A or 1B) in the EU harmonised classification and labelling and/or by a REACH registration dossier. More information about reproductive toxicity here.
- Ss – This substance was identified as a skin sensitiser (i.e. classified in skin sensitisation categories 1, 1A or 1B) in the EU harmonised classification and labelling and/or by a REACH registration dossier. More information about skin sensitiser here.
- Sr – This substance was identified as a respiratory sensitiser (i.e. classified in respiratory sensitisation categories 1, 1A or 1B) in the EU harmonised classification and labelling and/or by a REACH registration dossier. More information about respiratory sensitiser here.
- PBT – This substance was identified as persistent, bioaccumulative and toxic (PBT) by at least one REACH registrant (i.e. it is PBT/vPvB). More information about persistent, bioaccumulative and toxic substances here.
- POP – Recognised Persistent Organic Pollutant (POP): comes from an entry in the Annex I, II or III to the POPs Regulation and/or an entry in the Annex A, B or C to the Stockholm Convention. Under assessment as Persistent Organic Pollutant: is shown for substances that have been proposed for their inclusion in the Stockholm Convention and are under assessment, or for which a proposal is under preparation in the European Union. Note that proposals that have been set aside, either before their submission by the EU to the Convention, or by the POP Review Committee are still indicated as "Under assessment as POP".
The substance properties displayed in this section (with the exception of PBT properties) are derived from harmonised classification and labelling (CLH) and/or REACH registered dossier information. In case the substance classification is not harmonised and the substance is not registered the properties are derived from classifications provided in CLP notifications. PBT properties are derived from REACH registered substances dossiers.
Critical property indentification: Where less than 90% of the notifiers provide the same classification to derive the critical property, the border of this critical property icon is displayed as dashed.
Impurities or additives: When a specific critical property is associated with compositions with impurities and/or additives, the respective critical property icon has a * associated.
Please note: The icons in this section are only meant as visual indicators to help communicate information about the abovementioned critical properties. Unlike the pictograms in the ‘Classification and Labelling’ section, these icons are not determined by any legislative procedure and have the sole purpose of being informative in the context of InfoCards and Brief Profiles.
|
There is no overall agreement among data submitters, but a minority indicate they consider this substance as Carcinogenic (12.51% of REACH registrations). Of the minority indicating the property of concern, most indicate that it may relate to an impurity or additive rather than the substance itself. |
Regulatory context
The ‘Regulatory context’ section provides an overview of the regulatory activities that are related to the substance. For general information about any of the different regulations which currently fall under ECHA’s mandate please see the links below.
Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH)
The REACH Regulation (1907/2006) entered into force on 1 June 2007. The regulation aims improve the protection of human health and the environment from the risks that can be posed by chemicals, while enhancing the competitiveness of the EU chemical industry.
The REACH regulatory processes identified for the Brief Profile are:
- Registration
- Pre-registration – indicated if the substance is included in the list of pre-registered substances. Pre-registration allows companies to continue manufacturing and importing their phase-in substances for several years until the registration deadline is reached.
- Registration – indicated if there is at least one dossier registered and disseminated for the substance, how many non-confidential registrations are active and/or inactive and the type of submissions (joint and/or individual).
- Evaluation
- Dossier evaluation – indicated if at least one registered dossier for the substance has been evaluated under REACH for compliance check or testing proposal evaluation and associated decision(s) published on the ECHA website.
- Substance evaluation – indicated if the substance is or was included in the Community rolling action plan (CoRAP). The CoRAP list includes substances that could pose a risk to human health or the environment and whose (potentially hazardous) properties are to be evaluated by the Member States in the next three years. After evaluation, proposals may be made for further regulatory action regarding the substance.
- Authorisation
- Candidate List – indicates if the substance is included in the candidate list of substances of very high concern (SVHCs). The Candidate List includes substances that are subject to additional protocols and reporting obligations and which may eventually be included in the Authorisation list, further limiting their use.
- Authorisation list (Annex XIV) – indicates if the substance is included in the Authorisation List. These substances cannot be placed on the market or used after a given date, unless an authorisation is granted for their specific use, or the use is exempted from authorisation.
- Restriction
- Annex XVII (Restriction list) – indicates if the substance is included in the list of restrictions. The Restriction list describes the conditions for the manufacture, placing on the market or use of certain substances, either on their own or in mixtures or articles.
Persistent Organic Pollutants (POPs)
The POPs Regulation (EU) 2019/1021 entered into force on 15 July 2019, repealing the previous POPs Regulation (EC) No 850/2004. The regulation aims to protect human health and the environment by banning or severely restricting the production and use of persistent organic pollutants in the European Union.
The POPs regulatory processes identified for the Brief Profile are:
- List of substances subject to the POPs Regulation - Indicates if the substance is included in the POPs Regulation.
- List of substances proposed as POPs - Indicates if the substance has been proposed for its inclusion in the Stockholm Convention or if a proposal is under preparation in the European Union.
Classification, Labelling and Packaging (CLP)
The CLP Regulation (1272/2008) entered into force on 20 January 2009. The goal of CLP is to make sure that hazards presented by chemicals are clearly communicated to workers and consumers in the European Union through a system of classifying and labelling of chemicals.
The CLP regulatory processes identified for the Brief Profile are:
- Harmonised C&L– indicates if a European Union harmonised classifications and labelling has been assigned to the substance according to Annex VI to CLP and subsequent ATPs.
- Notification – indicates that notified C&L’s have been submitted to ECHA for a substance.
Biocidal Products Regulation (BPR)
The BPR (528/2012) entered into force on 1 September 2013. The BPR addresses the placing on the market and use of biocidal products, which are used to protect humans, animals, materials or articles against harmful organisms, like pests or bacteria, by regulating the active substances contained in a biocidal product.
The BPR regulatory processes identified for the Brief Profile are:
- Active substance approval – indicates if the substance is an approved biocidal active substance.
- Biocidal product authorisation – indicates if authorised biocidal products exist which use this substance as an active ingredient
Prior Informed Consent (PIC)
The PIC Regulation (649/2012) entered into force on 4 July 2014. PIC administers the import and export of certain hazardous chemicals and places obligations on companies who wish to export these chemicals to non-EU countries.
The PIC regulatory processes identified for the Brief Profile are:
- Annex I – indicates if the substance is subject to PIC.
- Annex V – indicates if the substance is prohibited from export.
Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)
Registration
- Pre-registration:
- Substance pre-registered under REACH.
- Registration:
- This substance has 674 active registrations under REACH, 1 Joint Submission(s) and 1 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
- Dossier Evaluation:
- Registration dossiers submitted to ECHA for this substance have been evaluated under REACH.
- Substance Evaluation:
Authorisation
- Candidate List:
- Annex XIV (Authorisation List):
Restriction
- Annex XVII (Restriction List):
Persistent Organic Pollutants Regulation (POPs)
- List of substances subject to the POPs Regulation:
- List of substances proposed as POPs:
Classification Labelling & Packaging (CLP)
- Harmonised C&L:
- A European Union Harmonised Classification & Labelling has been assigned to this substance.
- Seveso Annex I:
- Industrial accident prevention and reporting requirements have been established for this substance.
- Notified C&L:
- Classification & Labelling has been notified by industry to ECHA for this substance.
Biocidal Products Regulation (BPR)
- Active Substance:
- This substance is approved for use as a Biocidal Active Substance
- Biocidal Products:
Prior Informed Consent (PIC)
- Annex I:
- Annex V:
European Union Observatory for Nanomaterials (EUON)
- EUON:
About this substance
The ’About this substance’ section provides an overview of the volume in which this substance is manufactured or imported to the European Economic Area (EU28 + Iceland, Liechtenstein and Norway). Data for calculating the ’total tonnage’ band is extracted from REACH registered dossiers for the last year reported on the tonnage manufactured or imported, unless the tonnage band has been claimed confidential. The ‘total tonnage’ band published does not necessarily reflect the registered tonnage band(s).
For more information on total tonnage band calculation please consult the Data submission manual.
Additionally, if available, information on the use of the substance and how consumers and workers are likely to be exposed to it can also be displayed here. The information is aggregated from REACH registered dossiers provided by industry through a use descriptor system based on five separate descriptor lists which in combination with each other form a brief description of use and exposure for certain life cycle stage.
The use information is displayed per relevant life cycle stage of the substance.
- Manufacture stage includes processes by which the substance is manufactured from raw materials. Operations which are necessary for the handling of a substance on its own in the manufacturing for export or placing on the EU market are considered to be part of the manufacturing stage (e.g. filling into appropriate containers, storage or addition of stabiliser). If a substance is directly exported after manufacture, all activities with the substance will be reported under this stage.
- Formulation or re-packing stage corresponds to specific activities meant to produce a mixture to be placed on the market. This means that during formulation, the substance is transferred and mixed with other substances. It corresponds to activities taking place at industrial sites. This stage also includes chemical distributorsâ activities such as repacking (which involves transfer of the substance).
- End-use stage means the use of a substance as such or in a mixture (by professional workers (widespread uses), by consumers or at industrial sites), a last step before the end-of-life of the substance, namely before the substance is consumed in a process by reaction during use (including intermediate use), is emitted to waste streams or the environment or is included into an article.
- (Article) service life stage means the period of time a substance incorporated into an article remains in service or in use. Articles containing the substance can be used or processed by consumers, by workers at industrial sites and/or by professional workers. This also includes processing of semi-finished articles by workers with the aim of producing finished articles or repair and maintenance work like for example sanding of surfaces.
Use Descriptors
- The chemical product category (PC) describes the types of chemical products in which the substance is finally contained when it is supplied to end-users (by industrial, professional or consumer users). Examples include hydraulic fluids, perfumes and air care products. This category also describes uses as intermediate and under controlled conditions.
- The sector of use category (SU) describes in which sector of the economy the substance is used. This includes mixing or re-packing substances at the formulator’s level as well as industrial, professional and consumer end-uses (e.g. building and construction work or manufacture of food products).
- The process category (PROC) describes the application techniques or process types defined from the occupational perspective e.g. Industrial spraying, use in closed batch process (synthesis and formulation).
- The environmental release category (ERC) describes the broad conditions of use from the perspective of release to the environment (e.g. if the use occurs in industrial setting, if it is indoor use in long-life materials with a low release rate (e.g. flooring, furniture, toys, etc).
- The article category (AC) describes the type of article into which the substance has eventually been processed. This also includes mixtures in their dried or cured form (e.g. dried printing ink in newspapers; dried coatings on various surfaces).
Precautionary measures and safe use
This section provides information on the recommended measures to minimise or prevent adverse effects resulting from exposure to a hazardous product, or improper storage or handling of a hazardous product. The recommendations are based on the precautionary statements provided in REACH registration dossiers.
If information on guidance on safe use is available in REACH registered dossiers, a link is displayed. Information in the guidance on safe use section consists of recommendations by a substance registrant(s) on the proper use of the substance in various situations. Examples include recommended measures on fire-fighting, transport, recycling and disposal.
More information on the use descriptor system can be found in ECHA’s Guidance Chapter R.12: Use Descriptor system of ECHA’s Guidance on information requirements and chemical safety assessment.Please note:
Only non-confidential use descriptors are displayed and for readability purpose only use descriptors occurring in more than 5% of the total occurrences are displayed.
For a detailed overview on identified uses and environmental releases, please consult the detailed information from the registration dossiers.
Use descriptors were adapted from ECHA guidance to improve readability and may not correspond textually to descriptor codes description as in ECHA guidance chapter R.12: Use Descriptor system of ECHA Guidance on information requirements and chemical safety assessment.
Precautionary measures and guidance on safe use concern the use and handling of the specific substance, not of the presence of the substance in other articles or mixtures.
This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 000 000 tonnes per annum.
This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
This substance is being reviewed for use as a biocide in the EEA and/or Switzerland, for: human hygiene, disinfection, food and animals feeds, product preservation.
This substance is used in the following products: fuels.
Other release to the environment of this substance is likely to occur from: outdoor use, indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids) and indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters).
This substance is used in the following activities or processes at workplace: transfer of substance into small containers and the low energy manipulation of substances bound in materials or articles.
Release to the environment of this substance can occur from industrial use: manufacturing of the substance. Other release to the environment of this substance is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials), indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment) and indoor use in long-life materials with high release rate (e.g. release from fabrics, textiles during washing, removal of indoor paints).
This substance can be found in complex articles, with no release intended: machinery, mechanical appliances, electrical/electronic products not covered by Waste Electrical and Electronic Equipment (WEEE) directive (e.g. large-scale stationary industrial tools).
ECHA has no public registered data indicating whether or in which chemical products the substance might be used.
This substance is used in the following areas: scientific research and development and building & construction work. This substance is used for the manufacture of: , fabricated metal products, machinery and vehicles and electrical, electronic and optical equipment.
This substance is used in the following activities or processes at workplace: transfer of chemicals, closed, continuous processes with occasional controlled exposure, closed processes with no likelihood of exposure and roller or brushing applications.
Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids), indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use.
ECHA has no public registered data indicating whether or in which chemical products the substance might be used.
This substance is used in the following activities or processes at workplace: transfer of chemicals, transfer of substance into small containers, closed batch processing in synthesis or formulation, mixing in open batch processes, laboratory work, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure and batch processing in synthesis or formulation with opportunity for exposure.
Release to the environment of this substance can occur from industrial use: formulation of mixtures and in processing aids at industrial sites.
ECHA has no public registered data indicating whether or in which chemical products the substance might be used.
This substance is used for the manufacture of: chemicals, machinery and vehicles, textile, leather or fur, furniture, electrical, electronic and optical equipment and fabricated metal products.
This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure and laboratory work.
Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites, of substances in closed systems with minimal release and as an intermediate step in further manufacturing of another substance (use of intermediates).
This substance is used in the following activities or processes at workplace: transfer of chemicals, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, closed processes with no likelihood of exposure, laboratory work, batch processing in synthesis or formulation with opportunity for exposure and manual maintenance (cleaning and repair) of machinery.
Release to the environment of this substance can occur from industrial use: manufacturing of the substance, in processing aids at industrial sites and as an intermediate step in further manufacturing of another substance (use of intermediates).
Precautions for using this substance have been recommended by its registrants under REACH, as follows:
Prevention statements
When handling this substance: obtain special instructions before use; keep away from heat, sparks, open flames and/or hot surfaces – No smoking; use non-sparking tools; ground and bond container and receiving equipment; wash parts of the body (as specified by manufacturer/supplier)in contact with substance thoroughly after handling; do not handle until all safety precautions have been read and understood; do not breathe the dust, fume, gas, mist, vapours or spray; use explosion-proof equipment (electrical/ventilating/lighting/etc.); keep container tightly closed; take actions to prevent static discharges; do not eat, drink or smoke when using this product; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier.
Response statements
In case of incident: If swallowed: call a poison center or doctor/physician if you feel unwell. If on skin (or hair): take off immediately all contaminated clothing. Rinse skin with water or shower. If eye irritation persists get medical advice/attention. Immediately call a poison center or doctor/physician. If exposed or concerned: get medical advice/attention. In case of fire: Use (measures specified by manufacturer/supplier) for extinction. Rinse the mouth. If on skin: wash with soap and water. If in eyes: rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing.
Storage statements
Store this substance in a well-ventilated place and Keeping it cool; locked up; in a well-ventilated place and keeping container tightly closed.
Disposal statements
The substance must be disposed in accordance with local/regional/national/international regulation.
Guidance on the safe use of the substance provided by manufacturers and importers of this substance.
Registrants/suppliers
This section provides information on suppliers, importers or manufacturers of a substance (active and inactive) that have to register their substance under REACH.
Registration status | |
---|---|
Status in REACH-IT | Displayed in Brief Profile |
Active | Always as Active |
Cease manufacture | Always as Inactive |
Revoked registrations | Active/Inactive (pending). Due to ongoing appeals, all registrations flagged as revoked are published as Active pending the appeal outcome. When the appeal outcome is known, the registration will appear as Inactive |
Annulled registrations | In the case of a merge between two companies having a registration for the same substance, the higher tonnage band registration is maintained as active, and the other registration is annulled. The annulled registration is still legally valid and considered as an active registration, because the registration number could be present on safety fata sheets and may already be communicated throughout the supply chain. |
Under specific conditions, a registrant can claim confidentiality of their identity. If there is a confidentiality claim, an indication is provided with the tag [Confidential].
- "MYK" Gospodarstwo Hodowli Zarodowej S.C. Grzegorz Zając Mateusz Zając, Sulechówko 15 76-142 Malechowo Poland
- 3M Belgium BVBA/SPRL (OR1), Hermeslaan 7 1831 Diegem Belgium
- A V Pound & Co. Ltd, Goolds Hill House Old Cork Road Ireland Mallow Co. Cork Ireland
- Access Business Group International BV, Celsiusweg 20 Industrial Estate 4212 5928 PR Venlo Netherlands
- ACEITES VINOS Y ALCOHOLES S.A., Ctra Munera,5 02600 Villarrobledo Spain
- Achtel Sp. z o. o., Tysiąclecia 1 06-400 Ciechanów Mazowieckie Poland
- Acquavite S.p.A., Via Bosco 43 31020 Visnà di Vazzola (TV) Italy
- Acros Organics bv, Janssen Pharmaceuticalaan 3a B-2440 Geel Belgium
- ADM Europoort BV, Elbeweg 125 3198 LC Europoort Netherlands
- ADM Razgrad EAD, North Industrial Area POBox 239 7200 Razgrad Bulgaria
- ADM Services BV-Ethanol, Kingsfordweg 43-117 1043 GP Amsterdam Netherlands
- Adriaanse Import & Export, Adriaan Mulderweg 9-11 5657 EM Eindhoven Netherlands
- Aesop Netherlands B.V., Utrechtsestraat 93 H 1017VK Amsterdam Netherlands
- AGC Chemicals Europe, Ltd, World Trade Centre Zuidplein 80 1077XV Amsterdam Netherlands
- Agralco S. Coop. Ltda., Camino de Ordoiz, Nº 5 31200 Estella Navarra Spain
- AgrAlko AG Deutsche Agraralkohol, Neumarkter Straße 1 81673 München Germany
- AGRANA Stärke GmbH, Industriegelaende A-3435 Pischelsdorf Niederoesterreich Austria
- AGRO PLON Sp. z o. o., Nowe Przybojewo 09-151 Grodziec Poland
- AGRO-POL Kazimierz Pszczółkowski, Ogrodowa 2 26-307 Białaczów Poland Poland
- AGROMIAST Miasteczko Krajeńskie Sp. z o.o Brzostowo 10, Brzostowo 10 89-350 Miasteczko Krajeńskie Poland
- Agrár-Bioetanol Kft., Birkamajor 7200 Dombóvár Hungary
- AIR-VAL INTERNATIONAL S.A., POL.IND. CAMI RAL C/MIQUEL SERVET, 27 08850 Gavà Barcelona Spain
- ALBIOMA Saint Pierre, 13D avenue Charles Isautier ZI n°3 97410 Saint Pierre Réunion France
- Alco Bio Fuel NV, Pleitstraat 1 9042 Gent Belgium
- Alco Energy Rotterdam B.V., Merwedeweg 10 Havennummer 5629 3198LH Europoort Rotterdam Netherlands
- Alcodis SA, bld du Souverain 100 - bte 9 1170 Brussels Belgium
- ALCOHESPA, S.L, C/ Pensamiento nº 27, 3º Izquierda 28020 Madrid Spain
- ALCOHOLERA CATALANA S.A., Pasaje de la Estacion S/N 8730 Sta Margarida i Monjos Barcelona Spain
- ALCOHOLERA DE LA PUEBLA SA, CTRA. VILLACANAS S/N 45840 PUEBLA DE ALMORADIEL TOLEDO Spain
- Alcoholeras Reunidas, S.A., C/ Juan de Zúñiga, 184 13710 Argamasilla de Alba Ciudad Real Spain
- ALCOHOLES DE TOMELLOSO, S.A., AVILA, 4 Crta. de Argamasilla de Alba, Km 0,800 13700 TOMELLOSO Spain
- ALCOHOLES MONTPLET S.A, VIA TRAJANA 53 08020 BARCELONA Spain
- ALCOHOLES OLIVA S.A., Pasaje de la Estación S/N 08730 Sta. Margarida i Monjos Barcelona Spain
- Alcopro S.r.l, Via Montenapoleone , 8 20121 Milano Italy
- Alcotra Europe SA, Boulevard du Souverain 100 1170 Bruxelles Belgium
- Alcotra Spain S.L., PLAZA MIGUEL ASINS ARBÓ 9 BAJO, PTA 1 (EMPRENDIS) VALENCIA 46013 Valencia Spain
- ALCOVIN S.A., Ifaistou 2 15124 Marousi Greece
- Alfa Achievements S.à r.l., 16 Rue Erasme 1468 Luxembourg Luxembourg Luxembourg
- ALGARVE 1914, S.L., Ctra. Villacañas, 2 45710 Madridejos Toledo Spain
- ALL ONE ITALIA S.r.l.s., Via Piano del Principe n. 242/A 80040 Poggiomarino (NA) Italy
- Allnex Belgium NV/SA OR1, Anderlechtstraat 33 1620 Drogenbos Belgium
- Almagest EAD, 22, Patriarh Evtimiy Blvd. 1000 Sofia Sredets Bulgaria
- Alvinesa Natural Ingredients, S.A, Ctra. Valdepeñas, Km. 4,85 Apdo. de Correos, 16 13250 Daimiel Ciudad Real Spain
- Amador González Tojal Alcoholes, POLÍGONO LA LIENDE, 17 26338 SAN VICENTE DE LA SONSIERRA LA RIOJA Spain
- Anheuser Busch Inbev Brauerei Beck & Co Bremen, Am Deich 18-19 28199 Bremen Germany
- Anheuser-Bush InBev Deutschland, c/o Spaten-Franziskaner-Bräu GmbH Marsstr. 46-48 80335 München Germany
- Anora Group Plc, Kaapeliaukio 1 P.O.Box 350 FI-00101 Helsinki Finland
- AOT Energy Belgium, Boulevard de France 7 1420 Braine-l’Alleud Belgium
- APLOKS SIA, Tallinas ielā 37-10 LV1012 Rīga Latvia
- Arany Kapu Zrt., IV. k. 6. 6413 Kunfehértó Hungary
- Arcade Europe, 44 avenue George V 75008 PARIS France
- ARCTICA POLAND Sp. z o.o., Lenarty 5 19-400 Olecko Poland
- ARKEMA FRANCE, 420 rue d'Estienne d'Orves 92700 COLOMBES France
- Ashland Services BV (OR2), Noordweg 9 3336 LH Zwijndrecht Netherlands
- AustroCel Hallein GmbH , Salzachtalstrasse 88 5400 Hallein Austria
- Autumn 68 - Venture Capital, S.A., Rua Manuel Silva Leal, 7B - Escritório 6 1600-166 Lisboa Portugal
- AVANTI Spółka Jawna Fijałkowski i Spółka, Kujawska 9 87-860 Chodecz Poland Poland
- AZUCARERA DEL GUADALFEO, S. A., La Caleta 18680 SALOBREÑA GRANADA Spain
- AZUCARERA MONTERO S. A., Ctra. Molvizar S/N. 18610 SALOBREÑA GRANADA Spain
- AZUR DISTILLATION, 387, route de Cavaillon Coustellet 84660 Maubec France
- B-Lands Consulting (81111100-4), World Trade Center, 5 Place Robert Schuman - BP 1510 38025 Grenoble France France
- B-Lands Consulting (811472-7), World Trade Center, 5 Place Robert Schuman, BP 1516 38025 Grenoble France France
- B-Lands Consulting (811709-2), 5 Place Robert Schuman - BP 1516 38025 Grenoble France France
- Badische Staatsbrauerei Rothaus AG, Rothausstraße 1 79865 Grafenhausen Germany
- Bartscher GmbH, Franz-Kleine-Str. 28 33154 Salzkotten Germany
- BASF Antwerpen N.V., Haven 725, Scheldelaan 600 2040 Antwerpen 4 Antwerpen Belgium
- BASF Personal Care and Nutrition GmbH, Henkelstr. 67 40589 Düsseldorf Germany
- BASF SE, Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany
- BCS Only Representative Services Ltd 027, Pembroke House 30 Upper Pembroke Street Dublin 2 Dublin Ireland
- Beautyge, S.L., C/ Tirso de Molina, 40 08490 Cornella de Llobregat Spain
- Beauté Prestige International, 56 A Rue du Faubourg Saint-Honoré 75008 Paris France
- Becton Dickinson Distribution Center NV, Laagstraat 57 9140 Temse Belgium
- Beiersdorf Customer Supply GmbH, Unnastrasse 48 20253 Hamburg Germany
- Berner Ltd, Hitsaajankatu 24 00810 Helsinki Finland
- BG SPILIOPOULOS SA, 87 - 89 Akti Dymaion 26333 Patras Greece
- BGV, s.r.o., Hniezdne 471 06501 Hniezdne Slovakia
- BGW Sp. z o.o., Al. Wielkopolska 53/1 60-603 Poznan Wielkopolska Poland
- Big Bazar, Van der Madeweg 13 1114 AM Amsterdam - Duivendrecht Netherlands
- BIO FUEL ENERGY SRL, Portului No. 38 145400 Zimnicea Teleorman Romania
- BIO-BUT Sp. z o.o., Łabędzka 54 44-153 Sośnicowice Poland
- BIOAGRA S.A., Połczyńska 97A 01-303 Warszawa Poland
- Bioalter Sp. z o. o., - 86-330 Melno Poland
- Biocarburantes de Castilla y León, S.A., Carretera de Encinas a Cantalapiedra, Km. 5,2 37330 Babilafuente (Salamanca) Spain
- Bioenergie du Sud-Ouest, Rocade Sud d´Arance Plateforme Induslacq, porte d'Abidos 64300 Arance France
- Bioetanol AEG Sp. z o.o., Bydgoska 4 87-140 Chelmza kujawsko-pomorskie Poland
- Bioetanol Galicia, S.A., Poligono Industrial Teixeiro, Crta. Nacional 634, Km. 664,3 15310 Teixero-Curtis (A Coruña) Spain
- BIOFERM - lihovar Kolín, a.s., Havlíčkova 140 280 02 Kolín IV Czech Republic
- Biogaz Chocicza Sp.z o.o., ul. Parkowa 4 63-041 Chocicza Poland
- Biomin Biotech Sp. z o. o., Blok Dobryszyce ul. Przemysłowa 7 97-505 Dobryszyce Poland
- BIORIUS SPRL, Avenue Leonard de Vinci 14 1300 Wavre France
- Biowanze S.A., Avenue de Tervuren 182 1150 Bruxelles Belgium
- Bitburger Braugruppe GmbH, Römermauer 3 54634 Bitburg Germany
- Boeing Distribution, Inc. (d/b/a Aviall), Rudolf Diesel Strasse 11-13 24558 Henstedt-Ulzburg Germany Netherlands
- Boltze Ideen Deutschland GmbH & Co. KG, Alte Landstraße 42 22145 Braak Germany
- Borica Europe BVBA, Elzenstraat 31 3950 Bocholt Belgium
- Borregaard AS, Hjalmar Wessels vei 6 1701 Sarpsborg Norway
- BorsodChem Zrt. - OR, Bolyai ter 1. H-3700 Kazincbarcika Hungary
- BP Europa SE, Überseeallee 1 20457 Hamburg Germany
- BP Raffinaderij Rotterdam B.V., d'Arcyweg 76 3198 NA Europoort Rotterdam Netherlands
- Braskem Netherlands B.V., Weena 00240, C 9th floor NL - 3012 NJ PO Box 30128 3001 DC Rotterdam Netherlands
- Brauerei Gebr. Maisel KG, Hindenburgstr. 9 95445 Bayreuth Germany
- Brenntag Austria GmbH, Linke Wienzeile 152 1060 Wien Austria
- Brenntag Holding GmbH , Messeallee 11 45131 Essen Germany
- BrüggemannAlcohol Wittenberg GmbH, Bahnstr. 10 06886 Lutherstadt Wittenberg Sachsen-Anhalt Germany
- BrüggemannChemical, L. Brüggemann GmbH & Co. KG, Salzstrasse 131 74076 Heilbronn Baden-Württemberg Germany
- Bundesmonopolverwaltung für Branntwein, Friedrichsring 35 63069 Offenbach Germany
- C.S.B. GmbH 0260, Dujardinstr. 5 47829 Krefeld Germany
- CADES PENEDES, S.A., Camí Can Batlle, s/n 08793 Avinyonet del Penedés Barcelona Spain
- Cambridge Environmental Assessments part of RSK ADAS Europe (Ireland) Ltd (BS), Office Suite B, Bluebell Business Centre Old Naas Road D12XV7K Dublin Ireland
- Cambridge Environmental Assessments, part of RSK ADAS Europe (Ireland) Ltd, Office Suite B, Bluebell Business Centre, Old Naas Road D12XV7K Dublin Ireland
- Carbery Group, Ballineen Ballineen Co. Cork Ireland
- Cargill B.V., Evert van de Beekstraat 378 1118 CZ Amsterdam Schiphol North Holland Netherlands
- Cargill B.V. 2, Evert van de Beekstraat 378 NL-1118 CZ Airport Schiphol Netherlands
- Cargill Deutschland GmbH, Cerestarstrasse 2 47809 Krefeld Germany
- Cargill NV (UK-OR), Bedrijvenlaan 9 B-2800 Mechelen Belgium
- Cargill Poland Sp. z o.o., ul. Woloska 22 02-675 Warszawa Poland
- CAVALE, 16, Avenue du Pont de France 11300 Limoux France
- Caviro Extra SpA con SU, Via Convertite 8 48018 Faenza Ravenna Italy
- CCI Manufacturing Germany GmbH, Borsigstr. 12 41541 Dormagen Germany
- CCI Manufacturing Germany GmbH, Borsigstrasse 12 41541 Dormagen Germany
- CERPLON PPHU Sp.z o.o. w Cerekwicy, Cerekwica 88-400 Żnin Poland
- ChemCert Services GmbH, Mühlenweg 83 07751 Jena Germany
- Chemetall GmbH, Trakehner Str. 3 60487 Frankfurt Germany
- CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Regus Harcourt Centre D02 HW77 Dublin Ireland
- CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland
- Chemical Inspection & Regulation Service Limited, Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland
- CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre D02 HW77, Dublin, Ireland D02 Dublin Ireland
- Chemical Inspection & Regulation Service Limited, Regus Harcourt Centre D02 HW77 Dublin Ireland
- Chemical Inspection & Regulation Service Limited, Room 002, Regus Harcourt Centre D02 HW77 D02 Dublin Ireland
- Chemservice GmbH - (T6W5), Herrnsheimer Hauptstrasse 1b 67550 Worms Germany
- Circle K Ireland Fuel Trading Limited, Circle K House, Beech Hill, Clonskeagh D04Y016 Dublin 4 Ireland Norway
- Ciszkowo sp. z o.o. sp.j., Kręta 5 64-700 Ciszkowo WIELKOPOLSKIE Poland
- Clariant Product Ro Srl, 34 Londra Street 011764 Bucharest Romania
- Clariant Produkte (Deutschland) GmbH, August-Laubenheimer-Straße 1 Global Product Stewardship 65929 Frankfurt am Main Germany
- Coloplast Hungary Kft., Búzavirág út 15 2800 Tatabánya Hungary
- COMPANÍA ESPAÑOLA DE PETRÓLEOS, S.A (CEPSA), Torre Cepsa, Paseo de la Castellana 259A 28046 Madrid Spain
- COMPAÑIA CERVECERA DAMM, S.L., Del Pi, s/n 08820 El Prat de Llobregat Barcelona Spain
- Connect Chemicals GmbH, Kokkolastr. 2 40882 Ratingen Germany
- ConvaTec (Unomedical) Slovakia, Priemyselný park 3 071 01 Michalovce Slovakia
- Coopérative Syndicale Distillation Thouarcé et Vignobles du Layon, 10 Boulevard de la République THOUARCÉ 49380 BELLEVIGNE EN LAYON France
- Coscentra BV, Wenckebachstraat 12 6466NC Kerkrade Netherlands
- COSMETIQUE ACTIVE INTERNATIONAL, 28 rue du Président Wilson 03200 VICHY France
- Cosun Beet Company GmbH & Co. KG, Bluthsluster Strasse 24 DE-17389 Anklam Germany
- Coty Beauty Germany GmbH, Berliner Allee 65 64295 Darmstadt Germany
- Coty France , 14 rue du 4 Septembre 75002 Paris France
- Coty International B.V., Buitenveldertselaan 3-5 1082 VA Amsterdam Netherlands
- Coty Spain, S.L.U., Calla de la Marina 16-18, piso 16 Torre Mapfre 08005 Barcelona Spain
- Covestro (Netherlands) B.V., Urmonderbaan 22 6167 RD Geleen Netherlands
- CP Kelco ApS, Ved Banen 16 DK-4623 Lille Skensved Denmark
- CP Kelco Germany GmbH, Pomosin-Werk 5 DE-23775 Grossenbrode Germany
- CREMER OLEO GmbH & Co. KG, Glockengießerwall 3 20095 Hamburg Germany
- Cristal Union, 1 Rue Daddy 51430 Bezannes France
- Cristalco Iberica de Distribución y Trading S.L., Calle Ferraz 3-3º Dcha 28008 Madrid Spain
- Cristanol, 1 route départementale 20A 51110 Bazancourt France
- Croda EU B.V. (OR1), Westeinde 107 1601 BL Enkhuizen Netherlands
- CropEnergies Bioethanol GmbH, Albrechtstraße 54 06712 Zeitz Germany
- CS Regulatory IRL Ltd 1L-10, Alexandra House The Sweepstakes D04 C7H2 Dublin Ballsbridge Ireland
- CS Regulatory IRL Ltd 1L-16, Alexandra House The Sweepstakes D04 C7H2 Dublin Ballsbridge Ireland
- CS3 GmbH, Grauertstrasse 12 81545 Munich Germany
- CSI-OR03DUB, Block C Ardilaun Court 112-114 St. Stephen’s Green D02 TD28 Dublin Ireland
- CSI-OR06DUB, Block C Ardilaun Court 112-114 St. Stephen’s Green D02 TD28 Dublin Ireland
- CSI-OR36DUB, Block C Ardilaun Court 112-114 St. Stephen’s Green D02 TD28 Dublin Ireland
- CSI-OR50DUB, Block C Ardilaun Court 112-114 St. Stephen’s Green D02 TD28 Dublin Ireland
- Cyber Clean Europe GmbH, Enzianstraße 6 82319 Starnberg Germany
- Cölner Hofbräu P. Josef Früh KG, Robert-Bosch-Straße 17 50769 Köln Germany
- D'AURIA DISTILLERIE & ENERGIA SPA, C.da Caldari Stazione, 48 66026 Ortona Abruzzo Italy
- D.E.T.A.srl Distilleria, Strada di Poneta 2/16 50021 Barberino Val d'Elsa Toscana Italy
- Dako Denmark ApS, Produktionsvej 42 2600 Glostrup Denmark
- DCOOP. S.C. ANDALUZA, AVDA. DE LOS VINOS, 12 13600 ALCAZAR DE SAN JUAN CIUDAD REAL Spain
- DEKRA Assurance Services GmbH OR10, Handwerkstraße 15 70565 Stuttgart Germany
- Destilaria Levira, Lda, Rua de Cima - Levira 3780-174 S. Lourenço do Bairro Anadia Portugal
- DESTILERIAS SAN VALERO, S. COOP., CARRETERA DE VALENCIA, PKm. 451,7 50400 CARIÑENA (ZARAGOZA) Spain
- Destilerías Manchegas S. Coop., Alfredo Atienza, Nº 200 02630 La Roda Albacete Spain
- Destylacje Polskie sp. z o.o., Przemysłowa 9 64-600 Oborniki Wielkopolska Poland
- DESTYLARNIA FALMIEROWO Sp.z o.o., Przemysłowa 9 64-600 Oborniki Poland
- Destylarnia Maliniec Sp. z o.o., ul. Brunatna 19 62-510 Konin wielkopolskie Poland
- DESTYLERNIA KAMIEŃ Sp. z o.o., Kamień 143 24-335 Łaziska lubelskie Poland
- Deulep, 21 boulevard Chanzy 30800 Saint Gilles France
- Distelhäuser Brauerei Ernst Bauer GmbH & Co.KG, Grünsfelder Straße 3 97941 Tauberbischofsheim Germany
- Distilleria Bertolino S.p.A., Viale dei Platani, 101 90047 Partinico Palermo Italy
- Distilleria F.lli Russo snc, Via Duccio Galimberti n. 70 95010 Santa Venerina CT Italy
- Distillerie ARGELIERS, 13 Cours de la République 11120 ARGELIERS France
- Distillerie BARON, Carrefour de la Traque 44430 LA REMAUDIERE France
- Distillerie Bel, 4, Route de Florensac 34630 Saint Thibéry France
- Distillerie BONOLLO SpA, Via Mosca 5 41043 Formigine Modena Italy
- Distillerie Bonollo Umberto S.p.a., G. Galilei, 6 35035 Mestrino Italy
- Distillerie Chauvet, Saint Mont 32400 SAINT MONT France
- Distillerie coopérative d'Arzens, 247 avenue des vignerons 11 290 Arzens France
- Distillerie de Dordogne, 2 impasse de la distillerie 24100 Saint Laurent des Vignes France
- DISTILLERIE DE L'AUX, Moulin de Billy 89580 VALLAN France
- Distillerie de la Tour, 4 rue des Distilleries 17800 Pons France
- Distillerie Douence, 2 route de la distillerie 33670 Saint-Genès de Lombaud France
- Distillerie du Beaujolais, distillerie@distilleriedubeaujolais.fr 69220 Charentay France
- Distillerie du Bois des Dames, 1681, Le Plan de Dieu 84150 Violès France
- Distillerie du Sancerrois, Les Bruyères 18300 Crézancy-en-Sancerre France
- Distillerie Grands Crus, ZI de Pôme - Rue des Entrepreneurs 32100 Condom France
- Distillerie Guy NEYRAC, 1, Bagatelle 33220 Pineuilh France
- Distillerie JEAN GOYARD S.A, 52, Rue René Lalique 51160 Ay-Champagne France
- Distillerie Mazzari Spa, Via giardino, 6 48020 S.Agata sul Santerno (RA) Italy
- Distillerie Rivière du Mat, Site de Beaufonds - Chemin Manioc 97470 SAINT BENOIT La Réunion France
- Distillerie ROMANN & Cie, 17 rue du vieux Moulin Sigolsheim 68240 Kaysersberg Vignoble France
- Distillerie Saint Martin, 1 Coufi 33490 ST MARTIN DE SESCAS France
- Distillerie SEDEV, 20, Route du Perigord 24230 St Seurin de Prat France
- Distilleries vinicoles du Blayais, 85 route des bouilleurs de crus Marcillac 33860 Val de Livenne France
- DKSH France S.A., 1475 Quai du Rhone 01702 Miribel France
- Doe and Ingalls LTD, 25/28 North Wall Quay Dublin 1 Dublin Ireland
- DOMINA-ROL spółka z o.o., Stare Strącze 43 67-410 Sława Poland Poland
- Domsjö Fabriker, Domsjö Fabriker AB 891 86 Örnsköldsvik Sweden
- Dow Belgium B.V.B.A., Grotesteenweg 214 B-2600 Antwerpen (Berchem) Belgium
- DOW BENELUX B.V. OR-10, Postbus 48 4530 AA Terneuzen Netherlands
- DOW CHEMICAL IBERICA S.L., Ribera del Loira 4-6 Edificio Iris, 4º Planta 28042 Madrid Spain
- DSM Nutritional Products GmbH, Emil-Barell-Str. 3 79639 Grenzach-Wyhlen Germany
- DSP S.A.S., 22, rue Brunel 75017 Paris France
- DVT ESPAÑA, S.A., Ctra. Tomelloso-Socuellamos, Km.1'8 13700 CIUDAD REAL Spain
- East-West Chemicals Asset Management Limited, Stasinou 1 - 1505 Nicosia Cyprus
- Eastman Chemical B.V., Watermanweg 70 3067 GG Rotterdam Netherlands
- Eckart GmbH, Güntersthal 4 91235 Hartenstein Bavaria Germany
- Eckart GmbH - EA, Güntersthal 4 91235 Hartenstein Germany
- Ecoagrícola, Carretera N-343 Km7,5 30350 Cartagena Spain Netherlands
- Ecocarburantes Españoles,S.A., Carretera Nacional 343, km 7,5 Valle de Escombreras 30350 Cartagena Murcia Spain
- Ecofuel SpA, Via Felice Maritano 26 20097 SAN DONATO MILANESE Italy
- Ecolab Production Belgium B.V.B.A., Havenlaan 4 3980 Tessenderlo Belgium
- EcoMole s.r.o., U Vetrniku 40/1 16200 Praha Czech Republic
- EcoMundo (OR for COSMAX, INC), 195 rue Jean-Jacques Rousseau 92130 Issy-les-Moulineaux France
- EDF Trading Markets (Ireland) Limited, 9 Clanwilliam Terrace D02 H266 Dublin Ireland
- Efuma ApS, Kanalholmen 22 2650 Hvidovre Denmark
- Elementis Minerals B.V., Kajuitweg 8 1041AR Amsterdam Netherlands
- ENVIRAL, a.s., Trnavska cesta 920 41 Leopoldov Slovakia
- Equinor ASA, Forusbeen 50 N-4035 Stavanger Norway
- ESIM Chemicals GmbH, St.-Peter-Strasse 25 4020 Linz Austria
- Esso Norge AS, Grenseveien 6 4313 Sandnes Norway
- Estee Lauder N.V., Nijverheidsstraat 15 2260 Oevel Belgium
- Estonian Spirit OÜ, Merivälja tee 5-W409 11911 Tallinn Estonia
- ESTRELLA LEVANTE, S.A., Mayor, 171 30100 Espinardo Murcia Spain
- Ethanol Energy a.s., Skolská 118 28571 Vrdy Czech Republic
- Ethyl Chemicals, SIA, Kalmes, Salaspils pag., LV-2118 Salaspils novads Latvia
- Euro-Alkohol GmbH, Hans-Böckler-Straße 30 59348 Lüdinghausen Germany
- Evonik Italia S.r.l., Via Falconera, 7 26025 Pandino (CR) Italy
- EX-AGRO Spółka Z Ograniczoną Odpowiedzialnością, Wielka Wieś 64225 Kopanica Poland
- ExponentOR11I, Block 1, Blanchardstown Corporate Park Ballycoolen Road, Blanchardstown D15 AKK1 Dublin Ireland
- Faber-Castell AG, Nürnberger Str. 2 90546 Stein Germany
- Fabryka Wódek "POLMOS ŁAŃCUT" S.A., Kolejowa 1 37-100 Łańcut Podkarpackie Poland
- FERNANDO RIBEIRO ABREU, HERDEIROS, LDA, RUA PRINCIPAL 341 UNIAO FREGUESIAS ALCANENA VILA MOREIRA 2380-171 ALCANENA SANTARÉM Portugal
- Ferreira Gomes & Filhos, Lda, Vale Florido 2300-190 Tomar Santarem Portugal
- Ferro GmbH, Gutleutstr.215 60327 Frankfurt am Main Germany
- Finco Fuel Group BV, K.P van der Mandelelaan 120 3062 MB Rotterdam Netherlands
- Firma Frankiewicz Jarosław Frankiewicz, Gorzelniana 4 62-065 Grodzisk Wlkp. Poland
- Firma Handlowo Usługowo Produkcyjna PAMAREX s.c. Paweł Derdziak, Aleksandra Derdziak, Handlowa 10 64-150 Wijewo Poland Poland
- Font Salem S.L., Camino al Mar, s/n 46540 El Puig de Santa Maria Valencia Spain
- Fratelli Re spa, SS 33 del Sempione 51 20017 Rho Milano Italy
- G.M. EOOD, Poruchik Hr. Toprakchiev 1 1528 Sofia Bulgaria
- GAMAWIND Sp. z o.o., ul. Droga Dębińska 3a 61-555 Poznań Poland
- GEMEY PARIS - MAYBELLINE NEW YORK, 6 - rue du Paradis ORMES - BP226 45144 SAINT JEAN DE LA RUELLE France
- Gestora de Residuos Vinicos S. Coop. V. (GESTREVIN), Poligono Industrial Nuevo Tollo, Parcela M - 101 46300 Utiel Valencia Spain
- Givaudan France SAS - OR1, 55, Rue de la voie des Bans CS500024 95102 Argenteuil Cedex France
- Glencore International Import BV, Prinses Beatrixlaan 582 2595 BM Den Haag Netherlands
- Global Product Compliance (Europe) AB, IDEON, Beta 5, Scheelevägen 17 223 63 Lund Sweden
- Global Product Compliance (Europe) AB, IDEON, Beta 5, Scheelevägen 17, 22363 Lund Sweden
- Godavari Biorefineries B.V, Opaallaan 1180, 2132 LN - Hoofddorp, The Netherlands 2132 LN Hoofddorp Netherlands
- Gojo Luxembourg S.à r.l., 1 rue jean piret L-2350 Luxembourg Luxembourg
- Gorimex Sp.z o.o., Grodziec 9 59-516 Zagrodno Poland Poland
- Gorzelnia JARPOL, Parkowa 16/7 78-650 Mirosławiec Zachodniopomorskie Poland
- GORZELNIA RADZICZ SPÓŁKA Z OGRANICZONĄ ODPOWIEDZIALNOŚCIĄ, Radzicz 40 89-110 Sadki powiat nakielski, woj. KUJAWSKOPOMORSKIE Poland
- Gorzelnia Rolnicza Andrzej Paszota, Podole Wielkie 22 76-220 Główczyce Poland Poland
- Gorzelnia Rolnicza Kraplewice - Janusz Szamrowicz, Kraplewice 39 86131 Jezewo Poland
- Gorzelnia Rolnicza Krasne Dłusko Jerzy Pacan, Nowa Niedrzwica 42 66-340 Przytoczna Poland Poland
- GORZELNIA ROLNICZA ROSTKOWSKI ZBIGNIEW ROSTKOWSKA ALINA, Zybułtowo 14 - 107 Gierzwałd Poland
- Gorzelnia Rolnicza Stanisław Szukalski, Babimojska 2d 66120 Kargowa Poland
- Gorzelnie Jagiełło Sp. z o.o., GMINNA 57 22-100 CHEŁM - POKRÓWKA LUBELSKIE Poland
- Gospodarstwo Ekologiczne "Przytoczno" Grazyna Kraciuk, Przytoczno 15/1 21-146 Jeziorzany Poland
- Gospodarstwo Rolne "EDEN" Sp. z o.o., Gwiździny 13-300 Nowe Miasto Lubawskie Poland
- Gospodarstwo Rolne Bartężek Spółka z.o.o, Bartężek 1 14-300 Morąg Poland
- Gospodarstwo Rolne KAMIENICA Sp.z o.o., Kamienica 16 89-520 Gostycyn Poland Poland
- Gospodarstwo Rolne Maria Szczygielska, Grzybiny 13-214 Uzdowo warmińsko-mazurski Poland
- Gospodarstwo Rolne Raszewy Sp. z o. o., Gorzelnia Żółków Raszewy 69 63-210 Żerków Poland
- GOSPODARSTWO ROLNE ROLPOL SPÓŁKA Z OGRANICZONĄ ODPOWIEDZIALNOŚCIĄ W OSTROWITEM, Ostrowite 13-334 Ostrowite Poland
- Gospodarstwo Rolne Szewno Śliż Spółka Jawna, Szewno 10 86-182 Świekatowo Poland
- Gospodarstwo Rolne TIM-POL Piotr Duda, Rudna 31 89-320 Wysoka Poland
- GOSPODARSTWO ROLNE WABCZ SP. Z O.O., WABCZ 60 86-212 WABCZ 60 KUJAWSKO-POMORSKIE Poland
- GP Global ARA, 16th Floor, Wilhelminaplein 1 3072 DE Rotterdam Netherlands
- Greenfield Global LFS Ireland Ltd, IDA Business & Technolgy Park IRELAND Portlaoise Co. Laois Ireland
- GREENOVATION CONSULTING, S.L, Plaza de Villasis 2 41003 Sevilla Sevilla Spain
- GRUPA AWW Spółka z ograniczoną odpowiedzialnością, Niedźwiady 45 62-800 Kalisz Wielkopolska Poland
- Grupa Producencka Agro-Żabice Sp. z o. o., Żabice 52 59-140 Chocianów Poland
- Gunvor Services AS, Tornimäe 5 10145 Tallinn Estonia
- Győr Distillery and Refinery Co. Ltd., Budai 7/A H-9027 Győr Hungary
- Hartree Germany GmbH, Ballindamm 39 Buro 25 20095 Hamburg Germany
- Hellenic Petroleum R.S.S.O.P.P. S.A., 8A Chimarras street 15125 Marousi Attica Greece
- Henkel Global Supply Chain B.V., Gustav Mahlerlaan 2970 1081 LA Amsterdam Netherlands
- HFC Prestige Manufacturing Germany GmbH, Berliner Allee 65 64295 Darmstadt Germany
- HGBS Finanse Spółka Akcyjna, Monopolowa 4 51-501 Wrocław Poland
- HH Compliance, The Rubicon Centre, CIT Campus, Bishopstown, Cork Ireland
- HH Compliance Ltd., The Rubicon Centre, CIT Campus, 0000 Bishopstown, Cork Ireland
- HH Compliance Ltd., Unit 11D Nutgrove Office Park Nutgrove Avenue 14 Rathfarnham Dublin Ireland
- Hitachi Europe GmbH, Niederkasseler Lohweg 191 40547 Düsseldorf Germany
- Hodowla Roślin Strzelce Sp.z o.o. Grupa IHAR, ul. Główna 20 99-307 Strzelce woj. łódzkie Poland
- Hodowla Ziemniaka Zamarte Spółka z o.o. Grupa IHAR, Zamarte 33 89-430 Kamień Krajeński woj. kujawsko-pomorskie Poland
- Honeywell Advanced Limited OR, Riverview House, Harvey's Quay Apartments, Harvey's Quay V94R3DE Limerick Co. Limerick Ireland
- Hungrana Kft., Ipartelep 2432 Szabadegyháza Hungary
- I.M.E.R.A. srl, Via Trapani 1/D 90141 Palermo Italy
- Iberalcohol, s.l., Buzanca 13 28343 Valdemoro Madrid Spain
- IFF OR NL3, Liebergerweg 72-98 1221 JT Hilversum Netherlands
- IMA Polska Spółka akcyjna, ul. Polna 21 62-095 Murowana Goślina Poland
- INDENA SAS, 38, Avenue Gustave Eiffel 37095 TOURS France
- Industria Chimica Valenzana S.p.A., Via Desman, 428 35010 Borgoricco Italy
- Industria Meridionale Alcolici s.r.l., Viale dei Platani, 101 90047 Partinico Palermo Italy
- INEOS Derivatives Lavera SAS (Oxide), Avenue de la bienfaisance BP6 133117 Lavera France
- INEOS nv, Haven 1053 -- Nieuwe Weg 1 2070 Zwijndrecht Belgium
- Ineos Solvents Germany GmbH, Roemerstr. 733 47443 Moers Germany
- Ineos Solvents Germany GmbH (ORGrmth), Römerstr. 733 47443 Moers Germany
- Intechnica Consult GmbH, Ostendstrasse 181 90482 Nuernberg Germany
- Internacional de Alcoholes S.A., Pol Ind Alces, fase II, C/ Mencia, parc M80 13600 Alcazar de San Juan Ciudad Real Spain
- International Cosmetics and Chemical Services Ltd 302, 26 Pembroke Street Upper Suite 10016 D02 X361 Dublin 2 Ireland
- International Cosmetics and Chemical Services Ltd 322, 26 Pembroke Street Upper Suite 10016 D02 X361 Dublin 2 Ireland
- International Cosmetics and Chemical Services Ltd 324, 26 Pembroke Street Upper Suite 10016 D02 X361 Dublin 2 Ireland
- International Cosmetics and Chemical Services Ltd 331, 26 Pembroke Street Upper Suite 10016 D02 X361 Dublin 2 Ireland
- Intertek Deutsch GmbH 234, Stangenstrasse 1 70771 Leinfelden- Echterdingen Germany
- Intertek Deutschland GmbH 05, Stangenstrasse 1 70771 Leinfelden-Echterdingen Germany
- Intertek Deutschland GmbH 25, Stangenstrasse 1 70771 Leinfelden-Echterdingen Germany
- Intertek Deutschland GmbH 59, Stangenstrasse 1 70771 Leinfelden-Echterdingen Germany
- Intertek Deutschland GmbH 68, Stangenstrasse 1 70771 Leinfelden-Echterdingen Germany
- Intertek Deutschland GmbH CNFH, Stangenstrasse 1 70771 Leinfelden-Echterdingen Germany
- Intertek Deutschland GmbH GMAG, Stanfenstrasse 1 70771 Leinfelden-Echterdingen Germany
- Intertek Deutschland GmbH ILUX, Stangenstr.1 70771 Leinfelden- Echterdingen Germany
- Intrade sp. z o.o., Łukowo 10 64-600 Oborniki Poland
- ITW Performance Polymers, A Division of ITW Ireland, Bay 150 Shannon Industrial Estate V14 DF82 Shannon Co. Clare Ireland
- IVICT Europe GmbH, Kennedydamm 19 40476 Düsseldorf Germany
- Jaunpagasts Plus, Kalna 9 3292 Virbi, Talsi district Latvia
- JCS Race Technology, Dyrskueveien 30 2040 Klofta Ullensaker Norway
- JSC Grindeks, 53 Krustpils St LV 1057 Riga Latvia
- JSR Micro n.v., Technologielaan 8 3001 Leuven Belgium
- JT International Germany GmbH - FF, Diedenhofener Strasse 20-30 54294 Trier Germany
- JT International Germany GmbH - JT, Diedenhofener Strasse 20-30 54294 Trier Germany
- JTI Polska Sp. z o.o., Stary Gostków 42 99-220 Wartkowice Poland
- Jungbunzlauer S.A., Z.I. et Portuaire B.P. 32 67390 Marckolsheim France
- KALL Ingredients Kft, Fehértó part 1. 5211 Tiszapüspöki Jász-Nagykun-Szolnok Hungary
- KALSNAVAS ELEVATORS, SIA , Rūpnīcas iela 15 LV-4860 Jaunkalsnava, Kalsnavas pag., Madonas nov. Latvia
- Kalundborg Refinery A/S, Melbyvej 10 4400 Kalundborg Denmark
- Kao Chemicals Europe, S.L. (2), Puig dels Tudons, 10 08210 Barbera del Valles Barcelona Spain
- KCC Europe GmbH, Hansaring 61 50670 Köln Germany
- Kemetyl AB , Rörvägen 7 13650 Jordbro Sweden
- Kerona Scientific Ltd, 14 Thomas Hand Street K34 A375 Skerries Dublin Ireland
- KiK Textilien und Non-Food GmbH, Siemensstrasse 21 59199 Boenen Germany
- King Industries International, Science Park 402 1098 XH Amsterdam Amsterdam Netherlands
- Knoell NL-OR-S01, Agro Business Park 75 6708 PV Wageningen Netherlands
- Knoell NL-OR-S08, Agro Business Park 75 6708 PV Wageningen Netherlands
- Knoell NL-OR-S27, Agro Business Park 75 6708 PV Wageningen Netherlands
- Kolmar NL BV, Claude Debussylaan 10 1082MD Amsterdam Netherlands
- Koopman International B.V., Distelweg 88 1031 HH Amsterdam Netherlands
- KOSMOLATS, SIA, Lizuma iela 5L LV-1006 Rīga Latvia
- Kraul & Wilkening u. Stelling GmbH, Lohweg 39 30559 Hannover Germany
- Krnovský lihovar spol. s r.o., Čsl. armády 921/60 794 01 Krnov - Pod Cvilínem Czech Republic
- KTR Europe GmbH, Mergenthalerallee 77 65760 Eschborn Germany
- Kulmbacher Brauerei AG, Lichtenfelser Straße 9 95326 Kulmbach Bayern Germany
- König Brauerei GmbH, Friedrich-Ebert-Straße 255 - 263 47139 Duisburg Germany
- L OREAL ESPANA S.A., Calle Josefa Valcárcel núm. 48 28027 MADRID Spain
- L'OREAL, 14 rue Royale 75008 Paris France
- L'OREAL BELGILUX S.A., Parc Scientifique Erasme Allée de la Recherche 63 - Anderlecht 1070 BRUXELLES Belgium
- L'OREAL CESKA REPUBLIKA s.r.o., Plzenska 11/213 150 00 PRAGUE 5 Czech Republic
- L'OREAL DANMARK A/S, Stationsparken 37 2600 GLOSTRUP Denmark
- L'OREAL DEUTSCHLAND GmbH, Herzstrasse 175 D-76187 KARLSRUHE Germany
- L'OREAL ITALIA S.p.A., Via Primaticcio n°155 20147 MILANO Italy
- L'OREAL POLSKA Sp. z.o.o., 4 rue Daniszewska 03-230 VARSOVIE Poland
- L'OREAL PRODUITS DE LUXE INTERNATIONAL, 106 rue Danton 92300 LEVALLOIS PERRET France
- LA ALCOHOLERA DE LA RIOJA, EBRO Y DUERO, S.A., Avenida Ruiz Azcarrga s/n 26350 CENICERO LA RIOJA Spain
- LANCOME PARFUMS ET BEAUTE & Cie, 29, rue du Faubourg Saint Honoré 75008 PARIS France
- Lantmannen Agroetanol AB, Hanholmsvägen 69 602 38 Norrköping Sweden
- Lantmännen Reppe AB, Jungmansgatan 8 531 40 Lidköping Sweden
- LCNBV-OR-Tucsola, Delftseplein 27E 3013 AA Rotterdam Netherlands
- Leiber GmbH, Hafenstrasse 24 49565 Bramsche Germany
- Leiber Sp. z o.o., Łęczycka 38 99-340 Krośniewice Poland
- Leica Biosystems Nussloch GmbH, Heidelberger Straße 17-19 69226 Nussloch Germany
- Lesaffre Culinary Strasbourg, 5 route du Rohrschollen F - 67026 Strasbourg cedex France
- Lesta, Rudaminos 1a LT-13275 Skaidiskes, vilnius Lithuania
- Lihovar a likérka Velká Polom spol. s r.o., Opavská 171 747 64 Velká Polom Czech Republic
- Lihovar Budeč spol. s r.o., Knínice 22 588 56 Telč Czech Republic
- LIHOVAR Dvoriste, spol. s r. o., Simpach-Dvoriste 19 39501 Pacov Vysocina Czech Republic
- LiquiB Zamecky ovocny lihovar Blatna s.r.o., Plzenska 315 38801 Blatna Czech Republic
- Lisam Telegis (representing Nitro Química), Parc d'activités de Noyon-Passel 17 rue de la Couture 60400 Passel France
- Loewen-Brennerei GmbH, Karl-Lehr-Strasse 23 67363 Lustadt Germany
- LOUIS DREYFUS COMPANY ROTTERDAM B.V., Westblaak 92 3012 KM Rotterdam Netherlands
- Lubrizol Europe Coordination Center BVBA 02 , Chaussee De Wavre 1945 Brussels Belgium
- Lubrizol France SAS, 25 Quai de France 76100 ROUEN France
- Lumea Europe OÜ, Kristiine linnaosa Keemia tn 4 10616 Tallinn Estonia
- LUX ALCOHOL LTD, 42, Georgi Sava Rakovski Str., 3rd floor 1202 Sofia Bulgaria
- Lyondell Chemie France S.A.S., Zone Industrielle Portuaire 13270 Fos sur Mer France
- Lyondell Chemie Nederland B.V., Deltseplein 27E 3013 AA Rotterdam Netherlands
- Maisons du Monde France SAS, Le Portereau - BP52402 44124 VERTOU CEDEX France
- MANE OR Wayne, 620 route de Grasse 06620 LE BAR SUR LOUP France
- MARQUIS ENERGY GLOBAL PTE. LTD, Calle Juan de Mena, 10 - Planta 1, Puerta D 079015 Madrid Madrid Spain
- Małgorzata Głowa Gospodarstwo Rolne w Miłkowie, Miłkowo 1 78-553 Broczyno Poland
- Meliora Bio, Asnæsvej 16B 4400 Kalundborg Denmark
- Merck KGaA, Frankfurter Strasse 250 64293 Darmstadt Germany
- MERCK MILLIPORE LIMITED, Tullagreen -- Carrigtwohill Cork Ireland
- MHM Holding GmbH, Sonnenallee 1 D-85551 Kirchheim Germany
- Mitsui and Co. Deutschland G.M.B.H. Head Office (Düsseldorf), Herzogstrasse 15 D-40217 Düsseldorf Germany
- Momentive Performance Materials GmbH, Chempark, Building V7 PO 4502311119 51368 Leverkusen NRW Germany
- Monument Chemical, Haven 1972 Ketenislaan 3 9130 Kallo Belgium
- MORAVSKÝ LIHOVAR KOJETÍN a.s., Padlých hrdinů 927/865 752 33 Kojetín Czech Republic
- mostos vinos y alcoholes sa, Mompó 2 13610 Campo de Criptana Ciudad Real Spain
- MOTOR OIL (HELLAS) CORINTH REFINERIES S.A., Irodou Attikou 12a 15124 Marousi Athens Greece
- MV2tech, Rue dieudonné lefèvre 17 1020 Bruxelles Belgium
- NAM & NAM Europe GmbH, Am Kronberger Hang 2 65824 Schwalbach Germany
- Nedstar BV, Nicolaas Beetsstraat 114H 1054XT Amsterdam Netherlands
- Neste Oyj, Keilaranta 21 FI-02150 Espoo Finland
- Next Retail (Ireland) Limited, 13-18 City Quay D02 ED70 Dublin 2 Ireland
- NOF METAL COATINGS EUROPE, Bouwelven 1 Industriezone Klein-Gent 2280 Grobbendonk Belgium
- Nordbrand Nordhausen GmbH, Bahnhofstraße 25 99734 Nordhausen Germany
- Nordzucker AG, Küchenstraße 9 38100 Braunschweig Germany
- North European Oil Trade Oy, Urho Kekkosen Katu 5C, 5th Floor 00100 Helsinki Finland
- Nouryon Pulp and Performance Chemicals AB, Gamlestadsvägen 18 SE-415 02 Göteborg Sweden
- Nouryon Surface Chemistry AB, Box 47067 40258 Göteborg Sweden
- NWL FRANCE SERVICES, 738, rue Yves Kermen 92100 Boulogne Billancourt France France
- NYX PROFESSIONAL MAKEUP SPRL/BVBA, Avenue Charles-Quint 584 1082 Berchem-Sainte-Agathe Belgium
- OCI Fuels B.V. , Willemsparkweg 193 1071 HA Amsterdam Netherlands
- Only representative (No publishable name), null
- Oro Clean Chemie s.r.o., Vinohradská 2828/151 Žižkov 130 00 Praha 3 Czech Republic
- Otentic Customs BV, Zeilmakerij 8 4906 CW Oosterhout Netherlands
- OÜ DAXIN Baltic, Suur-Paala 5 13619 Tallinn Estonia
- P.P.H.U. AGROKOMPLEKS Sp. j.Wyborska & Wyborski, Polski Konopat 12 86-105 Świecie Poland
- P.P.H.U. ZABOROWICZ, Popowo Kościelne 37 62-285 Popowo Kościelne Wielkopolska Poland
- P.P.H.U."HARTWIG" Bogumiła Hartwig, os. Parkowe 2 64-630 Ryczywół Poland
- Paderborner Brauerei GmbH, Halberstädter Straße 45 33106 Paderborn Germany
- Pannonia Bio Zrt., Zrínyi u. 16. I. em. 1. 1051 Budapest Hungary
- Parker Hannifin Manufacturing Germany GmbH & Co. KG, Ottostrasse 28 41836 Hueckelhoven Northrhine Westfalia Germany
- Pelikan Vertriebsgesellschaft mbH & Co. KG, Werftstraße 9 30163 Hannover Germany
- PESCADO, SIA, Vaļņu iela 48 LV-5401 Daugavpils Latvia
- PetroChina International (Netherlands) Company B.V, Toren A, 11th Floor 3012NJ Rotterdam Netherlands
- Pfungstaedter Brauerei Hildebrand GmbH&Co.KG, Eberstaedter Str. 89 D-64319 Pfungstadt Hessen Germany
- PHU ABAPOL Gosp. Rolno-Przemyłowe Bińcze Sp. z o.o., Kijno 1 77-330 Czarne Pomorskie Poland
- PILOT CORPORATION OF EUROPE, PAE de la Caille 74350 ALLONZIER LA CAILLE France
- PIOTRKOWSKI Sp. z o.o., ul. Marii Konopnickiej 8 21-210 Milanów Lubelskie Poland
- PMC Vlissingen Netherlands B.V., De Fruittuinen 6 2132 NZ Hoofddorp Netherlands
- PN Bioethanol Elbewerk GmbH & Co. KG, Gustav-Elster-Straße 1 26789 Leer Germany
- Podlaskie Gorzelnie "SURWIN" Sp. z o.o., Suchowola 105 21-310 Wohyń Poland
- Polieuro Spółka z o.o., Nieżychowo 3, 89-340 Białośliwie Poland
- Polymer Solutions Ibérica, S.L.U., Valle de Tamón - Nubledo Att: Javier Francos 33469 Tamón – Carreño Asturias Spain
- PPG Europe B.V. - OR1, Amsterdamseweg 14 1422 AD Uithoorn Netherlands
- PPHiU Gruntpol, Gościnna 23/25 62-800 Kalisz Poland
- PPHU "Gorzelnia Kryszkowice" Małgorzata Musiał, Kryszkowice 36 62-619 Sadlno Poland
- PPHU Gorzelnia Skrzatusz Jakub Paprocki, Skrzatusz 96 64-930 Szydłowo Poland
- PPHU Zbig-Rol, Prusinowice 7 98-240 Szadek Poland Poland
- PPN "Centrala Nasienna" Sp. z o.o., Krakowska 111 33-100 Tarnow Poland
- PPRUiH "Róż-Pol" Spółka z o.o., Różanna 62-436 Orchowo Poland
- PPUH "SOBPOL"S.J. SOBOLEWSCY, Konopnica 96-200 Konopnica 102 Rawa Mazowiecka Poland
- Preem AB, Warfvinges väg 45 11280 Stockholm Sweden
- PRESTIGE ET COLLECTIONS INTERNATIONAL, 16 place Vendôme 75001 PARIS France
- Privatbrauerei Eichbaum GmbH & Co. KG, Käfertaler Straße 170 68167 Mannheim Germany
- Procter & Gamble Manufacturing Belgium N.V., Temselaan 100 1853 Strombeek-Bever Belgium
- Procter & Gamble Marketing Romania, 9-9A Dimitrie Pompei Blvd. Sector 2 BUCURESTI Romania
- Procter & Gamble Nederland B.V., Watermanweg 100 3067 GG Rotterdam Netherlands
- Procter & Gamble – Rakona s.r.o., Ottova 402 269 32 Rakovnik Czech Republic
- Procter and Gamble Operations Polska Sp. z o. o., Zabraniecka Street 20 03-872 Warsaw Poland
- PRODALCOM S.A. , PUSKIN 128 710350 BOTOSANI BOTOSANI Romania
- PRODUCTOS CAPILARES L'OREAL S.A., Calle Lopez Bravo n°78 Poligono Industrial Villalonquéjar 09001 BURGOS Spain
- Produits Sanitaires Aéronefs, 1 Rue de Lamirault ZAE de Lamirault 77090 COLLEGIEN France
- PRODUKCJA, USŁUGI, HANDEL EXPORT-IMPORT "ANMER" MILAN MEJER, Rosnowo 89 76-042 Rosnowo Poland
- Proquimia S.A., Ctra. De Prats, 6 08500 Vic Spain
- PRYSE, S.A., Lisboa, 6. Pol. Ind. Cova Solera 08191 Rubi Barcelona Spain
- Przedsiebiorstwo AGROPIN sp. z o.o., Pinsko 89-200 Szubin Poland
- Przedsiebiorstwo Handlowo Uslugowe Translis Piotr Liskowski, Bosmanska 3 62-502 Konin wielkopolska Poland
- Przedsiębiorstwo Produkcji Handlu i Usług ROL-MI-GO Sp. z o.o., Jaskowice Legnickie 62 59-216 Kunice Poland Poland
- Przedsiębiorstwo Produkcyjno Handlowe Gorzelnia Rolnicza s.c. Radosław Stelmaszczyk, Irena Stelmaszczyk, Jeziorki 9 89-641 Nowa Cerkiew Poland Poland
- Przedsiębiorstwo Produkcyjno Handlowo Usługowe Alkado Kazimierz Zaborowicz, Kolejowa 2 62-301 Marzenin wielkopolskie Poland
- Przedsiębiorstwo Produkcyjno Handlowo Usługowe Wilor Spółka Jawna, Dretyń 62 77-200 Miastko pomorskie Poland
- Przedsiębiorstwo Produkcyjno-Handlowe Gorzelnia DĄBRÓWKA WLKP. Kazmierz Witwicki, Poznańska 7 66-210 Zbąszynek Poland Poland
- Przedsiębiorstwo Produkcyjno-Handlowo-Usługowe ROLPAKO Sp.z o.o. w Pakotulsku, Przechlewo 77-320 Przechlewo woj.pomorskie Poland
- Przedsiębiorstwo Rolno - Spożywcze " AGROBAŁT " Sp. z o.o., Dobrociechy 23 76-020 Bobolice Poland
- Przedsiębiorstwo Rolno Produkcyjno Handlowo Usługowe GOPASZ Sp.z o.o., Wojska Polskiego 37 56-300 Milicz Poland Poland
- Przedsiębiorstwo Rolno-Handlowe Konstantynów Sp. z o.o., Stanisława Platera 2 21-543 Konstantynów Poland
- Przedsiębiorstwo Rolno-Przemysłowe SMOGÓRY Spółka z o.o., Smogóry 41 69-220 Ośno Lubuskie woj. lubuskie Poland
- Przedsiębiorstwo Rolno-Usługowo-Handlowe Hodrol Sp.z o.o., Żabice 52 59-140 Chocianów Poland Poland
- Przedsiębiorstwo Usługowo Produkcyjne KOW-ROL Tadeusz Kowalski, Srebrna 46 09-411 Stara Biała Poland Poland
- Przedsiębiorstwo Wielobranżowe Eksport-Import Kraciuk Ryszard, Harcerska 16 20-805 Lublin Poland Poland
- Przetwórstwo Rolno Spożywcze GORZELNIA OSIEKI Sławomir Piechorowski, Sianowska 3 76-003 Osieki Zachodniopomorskie Poland
- Puma Energy Belfast Ltd, Airport Road West Belfast BT3 9EA Belfast United Kingdom (Northern Ireland)
- PWW Polmos S.A., Kolejowa 10 08-110 Siedlce mazowieckie Poland
- PĒRLE AV, SIA, Prūšu iela 104 – 1 LV- 1057 Rīga Latvia
- Radeberger Gruppe KG, Darmstädter Landstraße 185 60598 Frankfurt am Main Germany
- Raffineria di Milazzo S.C.p.A., Contrada Mangiavacca 98057 Milazzo (ME) Italy
- Ramboll Deutschland GmbH, Werinherstraße 79 Gebäude 32a 81541 München Bayern Germany
- Raízen Trading Netherlands BV, Muiderstraat 1 1011PZ Amsterdam North Holland Netherlands
- REACH GLOBAL SERVICES S.A., Rond Point Schuman, 6 B-1040 Brussels Belgium
- Reach Only Representative (Ireland) Ltd (CIE), VPR House Main St F12 FC64 Swinford Co. Mayo Ireland
- REACH24H CONSULTING GROUP, Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland
- REACH24H CONSULTING GROUP, Suite 1E, Paramount Court, Corrig Road, Sandyford, Dublin 18, Ireland Dublin 18 Dublin Ireland
- REACH24H CONSULTING GROUP, Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland
- REACH24H CONSULTING GROUP acts as OR for Global Cosmetics(China) Company Limited, Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland
- REACHLaw Ltd., Vänrikinkuja 3JK 21 FI-02600 Espoo Finland
- REACHLaw Ltd., Aleksanterinkatu 19 00100 Helsinki Finland
- Red Orchid Consulting Oy Ltd, Viherkallionkuja 3 I 59 02710 Espoo, Finland 02710 Espoo Finland
- REGARTIS s.r.o., Rubeška 393/7 19000 Prague Czech Republic
- REGARTIS s.r.o., Rubeška 393/7 190 00 Prague Czech Republic
- REPSOL TRADING SA, Calle Méndez Álvaro, 44 28045 Madrid Spain
- REVICO SNC, 2, Rue des fosses de Jarnouzeau 16100 Saint Laurent de Cognac France
- RHODIA OPERATIONS, 9 rue des Cuirassiers Immeuble Silex 2 Solvay 69003 LYON France
- Ricardo Nederland BV, Catharijnesingel 33 3511 GC Utrecht Netherlands
- Ro-Lech L. Zimniak, Dobieżyńska 53 64-320 Buk Poland
- Roche Diagnostics GmbH, Sandhoferstrasse 116 68305 Mannheim Germany
- ROQUETTE Frères, 1 rue de la haute loge 62136 LESTREM Cedex France
- ROZA-M, Zadarska 77 10000 Zagreb Croatia
- Ruhr-Petrol GmbH, Kehrwieder 11 20457 Hamburg Germany
- Rum Albrecht GmbH, Eppenser Weg 3 D-29549 Bad Bevensen Germany
- Ryssen Alcools SAS, Z.A. de l'Helle route de la Distillerie 59279 Loon Plage France
- S.C. AGROZIM Zbigniew Zimorodzki, Małgorzata Zimorodzka, Grzmiąca 11 78-450 Grzmiąca Poland
- S.C. MAREX S.A., SOSEAUA BUZAULUI, KM.7 810325 BRAILA ROMANIA Romania
- S.V.E. Société des Vins et Eaux-de-vie, Chez Guitton 17210 Saint-Palais-de-Négrignac Charente-Maritime France
- Sacchetto SpA, Via Circonvallazione,4 12030 Lagnasco (Cn) Piemonte Italy
- Sachsenmilch AG, An den Breiten 01454 Leppersdorf Germany
- SADIS, 2 Bois de Preuil 49560 Lys Haut Layon France
- Saint Louis Sucre S.A., Parc du Millénaire 2 35 rue de la Gare 75019 Paris France
- SARL LRV, LE RAFIDIN 51130 POCANCY France
- Sartorius Stedim Biotech GmbH, August-Spindler-Straße 11 37079 Göttingen Germany
- SAS Distillerie Champion Labet, 35, route de Beaune 21420 Savigny les Beaune France
- SAS Distillerie du Vouvray, 2524 Rue D'amboise La Croix Vaubrault 37210 Chancay France France
- SASMA BV, Willem Dreeslaan 301 8 2727 NE Zoetermeer Zuid-Holland Netherlands
- Sasol Chemie GmbH & Co. KG, Anckelmannsplatz 1 20537 Hamburg Germany
- Sasol Germany GmbH, Anckelmannsplatz 1 D-20537 Hamburg Germany
- SC ROMCHIM PROTECT SRL, com. Filipesti nr. 340A 607185 Filipesti Bacau Romania
- SC SCANDIC DISTILLERIES SA, Pantasesti nr 41 417256 Draganesti Bihor Romania
- SCA Distillerie Sud Languedoc, 76, avenue des Corbières 11200 Ornaisons France
- SCAD Les vignerons du Languedoc CAPESTANG, 41 avenue de la République 34310 CAPESTANG France
- SCAIDMURVIEL, 19, avenue Edouard BONNAFE 34490 Murviel-les-Béziers France
- SCAS Europe S.A./N.V., Leonardo Da Vincilaan 19 B-1831 Diegem Belgium
- Sedamyl SBE s.r.l, Via Monviso 2 12037 Saluzzo Piemonte Italy
- SEDAMYL spa, Via Monviso 24 12037 Saluzzo Piemonte Italy
- SEKAB Biofuels & Chemicals, Box286 89126 Örnsköldsvik Sweden
- Service Car Technology Vertriebs GmbH, Hasenkamp 4 22880 Wedel Germany
- Shell Trading Rotterdam B. V., Weena 505 3013 AL Rotterdam Netherlands
- Shin-Etsu Silicones Europe BV - ORA, Bolderweg 32 1332 AV Almere Netherlands
- SICA Agricole de la Vallée du Loing, BP 35 77460 SOUPPES SUR LOING France
- Siegfried PharmaChemikalien Minden GmbH, Karlstr. 15-39, 42-44 32423 Minden Nordrhein-Westphalen Germany
- SIGMA-ALDRICH CHEMIE GMBH, Riedstrasse 2 89555 Steinheim Germany
- SIGMA-ALDRICH CHIMIE SARL, 80 Rue de Luzais BP 701 38297 Saint Quentin Fallavier France
- Sigma-Aldrich Ireland Ltd, Vale Road . Arklow Co. Wicklow Ireland
- Silcompa spa, Via Fosdondo, 71/a 42015 Correggio Reggio Emilia Italy
- Sitmae REACH Services BV, Timmermanslaan 2 3601 GP Maarssen Netherlands
- Skup Zbóż Produkcja Mąk Eugeniusz Suchowiecki, MŁYNARSKA 6 77-310 DEBRZNO 5610000521 Poland
- Sladorana d.o.o., Šećerana 63 32270 Županja Croatia
- SLAUR SARDET SAS, 192 rue de la vallée 76600 LE HAVRE France
- Slovenske liehovary a likerky, a.s., Trnavska cesta 920 41 Leopoldov Trnavský kraj Slovakia
- Smak MIrosław Piotr Gorzelnia Łąkie, Łąkie 99 77-420 Lipka Poland
- Sociedade de Destilação da Longra, Lda, Estrada das Burrecas n.º 2A 2675-173 Beselga Tomar Portugal
- Sociedade Lusitana de Destilação, Casal do Bernardino Rua da Estação-Apartado 1 2354-908 RIACHOS RIACHOS Portugal
- SOCIETE ANONYME DE LA RAFFINERIE DES ANTILLES - SARA, TOUR TOTAL 24 COURS MICHELET 92800 PUTEAUX MARTINIQUE France
- SOCIETE BIC, 12 BOULEVARD VICTOR HUGO 92611 CLICHY France
- SOCIETE REUNIONNAISE DE PRODUITS PETROLIERS, ZI n° 1 CS 71169 97829 LE PORT CEDEX LA REUNION France
- SOCIETE VERMANDOISE INDUSTRIES, Route d'Epehy 80240 VILLERS FAUCON France
- Société de Fait Laurens, 7, Avenue de la Tour 12330 Clairvaux France
- Société des alcools du Tarn, 23, avenue Guynemer 81600 GAILLAC France
- Solanum Sp. z o.o., Główna 43A 89-620 Chojnice Silno Poland
- Solar Coating Solutions B.V., Urmonderbaan 22 6167 RD Geleen Netherlands
- SOLVAY SOLUTIONS NEDERLAND B.V., ENERGIEWEG 1 4791RN Klundert Netherlands
- SOPROCOS, ZI Le Moulin de tous vents GAUCHY - BP294 02106 SAINT QUENTIN Cedex France
- SORAD s. r. o., Radkovice u Hrotovic 111 675 59 Radkovice u Hrotovic Czech Republic
- St1 Oy, PL 68 00521 Helsinki Finland
- STAGRA Stanisław Gawin, Sowieński Młyn 1 76-004 Sowieński Młyn 1 Zachodniopomorskie Poland
- STEPAN EUROPE SA, Chemin JONGKIND 38340 VOREPPE France
- SUCRERIE DE TOURY ET USINES ANNEXES, Avenue de la sucrerie 28310 TOURY France
- Sun Chemical A/S 7, Københavnsvej 112 4600 Køge Denmark
- Sun Chemical B.V., Leeuwenveldseweg 3-t 1382 LV Weesp Netherlands
- Sun Chemical Nyomdafesték Kereskedelmi ès Gyarto KFT, Telek u. 7-9 H-1152 Budapest Hungary
- Suterra Europe Biocontrol S.L., Plaza America 2 Floor 9 46004 Valencia Spain
- Søstrene Grene, Mariane Thomsens Gade 1C, 6 8000 Århus C Denmark
- TAKASAGO TEG-importer, Industriestrasse 40 D-53909 Zülpich Nordrhein-Westfalen Germany
- TEDi GmbH & Co. KG, Brackeler Hellweg 301-305 44309 Dortmund NRW Germany
- Tereos Alcools, 11 Rue Pasteur 02390 Origny sainte Benoîte France
- TEREOS COMMODITIES FRANCE, rue de Senlis 77230 MOUSSY LE VIEUX France
- TEREOS DVO, 11 rue Pasteur 02390 ORIGNY SAINTE BENOITE France
- TEREOS FRANCE, 11 rue pasteur 02390 Origny sainte Benoîte France
- Tereos Grain Alcohols France, 46 Rue de Nesle - BP 49 80190 Mesnil Saint Nicaise France
- TEREOS STARCH & SWEETENERS BELGIUM, Burchtstraat 10 9300 Aalst Belgium
- TEREOS STARCH & SWEETENERS LBN, BP 80059 76170 Lillebonne France
- Tereos TTD, a.s., Palackého náměstí 1 29441 Dobrovice Czech Republic
- TERPIOR sp. z o. o., Kręta 3 37-403 Pysznica Podkarpackie Poland
- The Absolut Company AB, Box 83 29622 Åhus Sweden
- The Acta Group EU BVBA (BE38), Place du Luxembourg 2 1050 Brussels Belgium
- TIGI Haircare GmbH, Postfach 700331 70573 Stuttgart Germany
- TotalEnergies Marketing Deutschland GmbH, Jean-Monnet-Straße 2 10 117 BERLIN Germany
- TotalEnergies Marketing France, 562 AVENUE DU PARC DE L'ILE 92000 NANTERRE France
- TotalEnergies Marketing Réunion, 3 RUE JACQUES PREVERT RIVIERE DES GALETS - BP 286 97420 LE PORT LA REUNION France
- TotalEnergies Petrochemicals & Refining, Boulevard Anspach, 1 box 2 1000 Bruxelles Belgium
- TotalEnergies Raffinage France, 2, place Jean Millier, La Défense 92400 Courbevoie France
- TotalEnergies Trading Europe, 2 Place Jean Millier La Défense 6 92400 Courbevoie France
- Toyota Tsusho Europe S.A., Belgicastraat 13 1930 Zaventem Belgium
- TRADHOL INTERNACIONAL SAU, Cta. de Humera, 43 28224 Pozuelo de Alarcon Spain
- Trafigura Ventures V.B.V., Evert van de Beekstraat 1-82 The Base, Tower B, 5th floor 1118 CL Schiphol Netherlands
- Transpol Sp.z o.o., Lubelska 28 21-010 Łęczna Poland Poland
- Tremonis GmbH, Westfälische Straße 251 44309 Dortmund Germany
- Trepiet Józef, Ruskie Piaski 55 22-413 Nielisz Poland Poland
- TROY CHEMICAL COMPANY BV, Poortweg 4C 2612PA Delft Netherlands
- TSGE_2019-010, Im Fliegerhorst 12 38642 Goslar Germany
- Tudo Azul SA, Edifício Espace Alameda dos Oceanos Lote 1.06.1 .4 - Piso 3 - Bloco C 1990-207 Lisbon Portugal
- TÜV SÜD Iberia S.A.U. (009), Ronda Can Fatjó 13 08290 Cerdanyola del Vallès Barcelona Spain
- UAB "APLINKOS VADYBA", Vilkpėdės g. 22 03151 Vilnius Lithuania
- UAB "KURANA", Mūšos g. 19 39103 Pasvalio raj. Aukštikalnių k. Lithuania
- UAB ENVIROLLA, Manufaktūrų g. 20-216 11342 Vilnius Lithuania
- UCVA, 31 Rue Edouard Branly 33230 Coutras France
- UMCO GmbH, Georg-Wilhelm-Straße 187 21107 Hamburg Germany
- Union des Distilleries de la Méditerranée, 431 rue Philippe Lamour 30600 Vauvert France
- Union GRAP'SUD, 120, Chemin de la Regordane - 30360 Cruviers-Lascours France France
- Univar Solutions B.V., Schouwburgplein 30-34 NL-3012 CL Rotterdam Netherlands
- VA.PA srl, Via Toledo, 156 80132 Napoli Italy
- Varo Energy Netherlands B.V., Waalhaven z.z. 11 3089 JH Rotterdam Netherlands
- VEGA STIVIDORS, SIA, Ezera iela 22 LV-1034 Riga Latvia
- Venator P&A Spain S.L., Poligono Industrial Nuevo Puerto Calle A s/n 21810 Palos de la Frontera (Huelva) Spain
- VERBIO Schwedt GmbH, Passower Chaussee 111 Straße K 16303 Schwedt Germany
- VERBIO Zörbig GmbH, Thura Mark 20 06780 Zörbig Germany
- versalis S.p.A., P.zza Boldrini 1 20097 San Donato Milanese MILANO Italy
- VICOGO GmbH, Karlstr. 19 26123 Oldenburg Germany
- Videojet Technologies Europe B.V., Strijkviertel 39 3454 PJ De Meern Utrecht Netherlands
- Vignobles ARBEAU, 6 rue Demages 82370 Labastide Saint Pierre France
- VILLAPANA SPA, Via Pana 238-244 48018 Faenza Emilia Romagna Italy
- Vilniaus degtine AB, Paneriu 47/2 LT 03202 Vilnius Lithuania
- Vinisol Soc Vinicola Ribatejo LDA, Rua Dos Combatentes Do Ultramar, 17 2040-535 Malaqueijo Portugal
- VIRESOL Kft., top.lot.nr. 0158/5. 3271 Visonta Hungary
- Vitol Chemicals BV, K.P. van der Mandelelaan 130 3062 MB Rotterdam Netherlands
- VIUDA DE JOAQUIN ORTEGA, S.A., MENENDEZ PELAYO, S/N 02600 VILLARROBLEDO ALBACETE Spain
- VIÑAOLIVA, S. COOP., POLÍGONO INDUSTRIAL, PARCELA 4-17 CTRA. ARROYO SAN SERVAN KM 6.1 06200 ALMENDRALEJO EXTREMADURA Spain
- VP Brands International S.A., 5, Dunav Blvd. 4003 Plovdiv Bulgaria
- Werda s.c. Weronika Niekrasiewicz, Dorota Niekrasiewicz, Harcerska 18 63-000 Środa Wielkopolska Poland
- Wernesgrüner Brauerei GmbH, Bergstraße 4 08237 Wernesgrün Germany
- WIKI EU Sp. z o. o., Kamień 143 24-335 Łaziska Poland Poland
- Wilkinson Sword GmbH, Schuetzenstr. 110 42659 Solingen NRW Germany
- WOOLWORTH GmbH, Mönninghoffs Feld 5 59425 Unna NRW Germany
- WSP Deutschland A.G., Dingolfinger Straße 1-15 81673 München Germany
- Yordas GmbH, Äußere Nürnberger Str. 6 91301 Forchheim Germany
- Yordas GmbH, Äußere Nürnberger Str. 62 91301 Forchheim Germany
- Yordas GmbH, Äußere Nürnberger Straße 62 91301 Forchheim Germany
- Yordas GmbH OR200177, Äußere Nürnberger Str. 62 91301 Forchheim Germany
- YOU Solutions Germany GmbH - REACH (part of Arxada), Freundallee 9 a 30173 Hannover Germany
- Zaharni zavodi, 29, Sveti Knjaz Boris 1 29, Sveti Knjaz Boris 1 5100 Gorna Oriahovitsa Veliko Tarnovo Bulgaria
- Zakład Produkcyjno- Handlowy ZNICZ- Jadwiga Kopera, Grodkowo 21 09-450 Wyszogród Poland
- Zakład Rolny, Wiktor Chrzan, Główna 4 Wilczków 55-020 Żórawina Poland
- Zakłady Wytwórcze CHEKO sp.z o.o., Krzywa Góra 28 PL 87-800 Wloclawek Poland
- Zebra A/S, Strandgade 71-73 1401 Copenhagen Denmark
- Łyszczarz Sp. z o.o., Wysoka Strzyżowska 10 38-123 Wysoka Strzyżowska Poland
- ВИН.С. Индустийс ООД, с Церковски 8472 община Карнобат област Бургас Bulgaria
- [Confidential], [Confidential]
- "GORZELNIA" Sp. z o.o., Leopoldów 23 22-554 Trzeszczany Poland
- AB "Biofuture", Silo 4 LT-99149 Silute Lithuania
- Agro-Plon Elżbieta Woycicka, Olsztyńska 45 14-100 Ostróda Poland
- AGROMIS Sp.z o.o. Boguchwałą, Trzebiele 78-425 Biały Bór Poland Poland
- Albaad UK, The Cider House The Grange Business Park BS24 6RR Weston-Super-Mare North Somerset United Kingdom
- B-Lands Consulting (811216-9), World Trade Center, 5 Place Robert Schuman - BP 1516 38025 Grenoble France France
- Basildon Chemical Co. Limited, 7 Kimber Road OX14 1RZ Abingdon United Kingdom
- BCS Only Representative Services Ltd, Pembroke House 30 Upper Pembroke Street Dublin 2 Dublin Ireland
- Berkshire International, The Chapel 95 Ewell Road KT6 6AH Surbiton Surrey United Kingdom
- Bestseller A/S, Moltrup Landevej 201 6100 Haderslev Denmark
- Borealis AG, Trabrennstrasse 6-8 1020 Wien Austria
- Botanicals & Natural Products Ltd, Sterling House Stroudley Road RG24 8UG Basinsgtoke Hampshire United Kingdom
- BP Oil International, Chertsey Road TW16 7BP Sunbury on Thames Middlesex United Kingdom
- BP Oil UK Limited, Chertsey Road TW16 7BP Sunbury on Thames United Kingdom
- Bunge London Ltd, 2 White Lion Court Cornhill EC3V 3NP London United Kingdom
- CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Regus Harcourt Centre D02 HW77 Dublin Ireland
- CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre D02 HW77 D02 Dublin Ireland
- De Danske Gærfabrikker A/S, Bredstrupvej 33 8500 Grenaa Denmark
- Dinkelacker- Schwaben Bräu GmbH & Co. KG, Tübinger Strasse 46 70178 Stuttgart Germany
- DOW BENELUX B.V. - OR2, Postbus 48 4530 AA Terneuzen Netherlands
- ECO-Strom Plus GmbH Chemie, Paul-Schlack-Straße 3 14727 Premnitz Germany
- EcoMundo, 215, rue Jean-Jacques Rousseau 92130 Issy-les-Moulineaux France
- Ensus UK Ltd, The Granary 17a High Street TS15 9BW Yarm United Kingdom
- Equinor OTS AB, Gatan 118 88 Stockholm Sweden
- Europarfums, Industrieweg 53 2651 BC Berkel en Rodenrijs Netherlands
- Fuelstreamers Trading B.V., Keizersgracht 62/64 1015 CS AMSTERDAM Netherlands
- Gapuma(UK) Ltd, UNIT 4, KEY WHARF 8 KEW BRIDGE ROAD TW8 0FJ London United Kingdom
- Gillette U.K. Limited, The Heights, Brooklands, KT13 OXP Weybridge, Surrey United Kingdom
- GORZELNIA KOZŁOWO GRZEGORZ KWIECIEŃ, Kozlowo 13-124 Kozłowo Poland
- Gorzelnia Radosław Kulawczuk, Milejów 21-020 Łysołaje woj. lubelskie Poland
- Gorzelnia Rolnicza Barbara i Klaudiusz Kaminiarz, Poznanska 8 67-416 Konotop Wielkopolska Poland
- GORZELNIA ROLNICZA ZYGMUNT CICHOŃ, JAWTY WIELKIE 14-240 SUSZ Poland
- GOSPODARSTWO ROLNE KOMOROWO SP. Z O.O., KOMOROWO 22 87-322 JASTRZĘBIE KUJAWSKO-POMORSKIE Poland
- Gospodarstwo Rolne KRĄPIEWO Sp.z o.o., Krąpiewo 31 86-017 Wierzchucin Król. Poland Poland
- Gospodarstwo Rolne STRZELEWO Sp.z o.o., Strzelewo 20 86-014 Sicienko Poland Poland
- Gospodarstwo Rolne WOJNOWO Sp.z o.o., Wojnowo 5 86-014 Sicienko Poland Poland
- Gospodarstwo Rolne ŚLESIN Sp.z o.o., Dworcowa 35 89-121 Ślesin k. Nakła Poland Poland
- Greenergy Fuels Ltd, 198 High Holborn WC1V 7BD London United Kingdom
- GRUPA HAJDUK SPÓŁKA Z OGRANICZONĄ ODPOWIEDZIALNOŚCIĄ PODŁOŻE DO PIECZAREK SPÓŁKA KOMANDYTOWA, Ciepielówek 1 67-410 Sława Poland
- Helm AG, Nordkanalstraße 28 20097 Hamburg Germany
- Henkel Nederland B.V., Brugwal 11 3432 NZ Nieuwegein Netherlands
- HH Compliance Ltd, The Rubicon Centre CIT Campus, Bishopstown T12 Y275 Cork Cork Ireland
- Huntsman Textile Effects (Germany) GmbH, Rehlinger Str. 1 D-86462 Langweid a.Lech Germany
- INTERTEK FRANCE, ZAC Ecoparc II 27400 HEUDEBOUVILLE France
- Intertek Semko AB 06, Torshamnsgatan 43 SE-164 22 Kista Sweden
- ITOCHU FRANCE, 17, Square Edouard VII 75009 PARIS France
- ITS Testing Services (UK) Ltd 67, Caleb Brett House 734 London Road RM20 3NL West Thurrock Grays United Kingdom
- Kao Chemicals Europe, S.L. (12), Puig dels Tudons, 10 08210 Barbera del Valles Barcelona Spain
- Kemetyl Norge AS, Delitoppen 3 1541 Vestby Norway
- Knoell NL-OR-S23, Agro Business Park 75 6708 PV Wageningen Netherlands
- Knoell NL-OR-S30, Agro Business Park 75 6708 PV Wageningen Netherlands
- Komers International Franciszek Madry, Boczna 4 83-010 Straszyn Poland
- L OREAL UK LTD, 255, Hammersmith Road W6 8AZ LONDON United Kingdom
- LIHO-Blanice spol. s r.o., Blanice 11 39143 Mladá Vožice Czech Republic
- Morgan Stanley & Co. international Plc, 25 Cabot square E14 4QA London United Kingdom
- MTC PLUS Sp. z o.o., ul. Baranowicka 117 15-501 Białystok Poland
- Noble Clean Fuels Limited, 33 Cavendish Square W1G 0PW London United Kingdom
- Only representative (No publishable name), null
- Petrobras Global Trading B.V., Weena 798C – 23rd floor 3014 DA Rotterdam Netherlands
- PETROBRAS GLOBAL TRADING BV - PGT BV, Weena 798C – 23rd floor First Rotterdam 3014 DA Rotterdam Netherlands
- Petroleos del Norte, S.A., Ed. Muñatones, Bº San Martín, 5 48550 Muskiz Vizcaya Spain
- Petroplus Refining and Marketing Limited, Coryton Refinery The Manorway SS17 9LL Stanford-le-Hope Essex United Kingdom
- Podlaskie Gorzelnie "SURWIN" Sp. z o.o., Suchowola 105 21-310 Wohyń Poland
- PPHU MIROSŁAWA PINECKA, Bronisław 2 63-025 Witowo Bronisław Poland
- Prax Petroleum Ltd, Prax House Horizon Business Village KT13 0TJ 1 Brooklands Road Weybridge, Surrey United Kingdom
- Produkcyjno-Usługowe Przedsiębiorstwo "AGROPAMIS" Sp. z o. o., Wielka Łąka 87-410 Kowalewo Pomorskie Poland
- Przedsiębiorstwo Producentó Rolnych Spółka z Ograniczoną Odpowiedzialnością, Stara Wiśniewka 22 77-424 Zakrzewo Poland Poland
- Przedsiębiorstwo Rolne "Rolplon" Sp. z o. o., Pawłowice 1 63-210 Żerków Poland
- Przedsiębiorstwo Rolne Produkcyjno-Handlowo-Usługowe Książ-Rol Sp. z o.o., Radoszkowska 3 63-130 Książ Wlkp. Poland Poland
- Przedsiębiorstwo Rolno-Przemysłowe Spółka Jawna Krzysztof Borys, Damian Borys, Słosinko 13 77-200 Miastko pomorskie Poland
- R.C.Treatt & Co. Ltd., Skyliner Way IP32 7FR Bury St. Edmunds Suffolk United Kingdom
- Reach Only Representative (Ireland) Ltd (mgping), VPR House Main Street F12 FC64 Swinford County Mayo Ireland
- Repsol Petroleo, S.A., Calle Mendez Alvaro, 44 28045 Madrid Madrid Spain
- REPSOL POLIMEROS, UNIPESSOAL LDA, Monte Feio 7520-954 Sines Portugal
- RHODIA OPERATIONS - 44, 9 rue des Cuirassiers Immeuble Silex 2 Solvay 69003 LYON France
- RUNOWO-ROLA Społka z o.o., Runowo Krajeńskie 89-421 Krajeńskie Poland Poland
- RWE Supply & Trading GmbH, 60 Threadneedle Street EC2R 8HP London United Kingdom
- S.C. TOTAL MIHOC PROD SRL, not available 617415 Tamaseni Neamt Romania
- SBS S.p.A., Via Circonvallazione s/n 28010 Miasino Italy
- Shell Global Solutions Germany GmbH, (PAE) Produkte, Anwendung und Entwicklung Hohe-Schaar-Strasse 36, 21107 Hamburg Germany
- Shell Trading International Ltd, Shell Centre SE1 7NA London United Kingdom
- Shepherd Europe SARL PI, 275, rue de Lorraine 88500 Juvaincourt France
- Sherman Cosmetics FZE C/O Ashcombe Belgium NV, Vaartstraat 189C 2520 Oelegem Belgium
- Shiseido Americas Corporation, 6th Floor, 100 New Oxford Street WC1A 1HB London United Kingdom
- Shiseido Group UK Limited, 10th Floor, The Adelphi 1-11 John Adam St WC2N 6HT London United Kingdom
- Sigma-Aldrich Company Limited, The Old Brickyard, New Road SP8 4XT Gillingham United Kingdom
- Skład Podatkowy Fermy Koźlakiewicz Spółka Jawna, Wiśniewo 06-521 Wiśniewo k/Mławy Poland Poland
- solvadis commodity chemicals gmbh, Koenigsberger Strasse 1 60487 Frankfurt / M. Germany
- Spółka Pracownicza "ROL-DZWIERZNO" Sp. z o. o. Gorzelnia Rolnicza w Dzwierznie, Dzwierzno 87-140 Chełmża Poland
- Tampieri S.p.A., Via Granarolo 177/3 48018 Faenza Italy
- TJ Morris Ltd, 50 Bedford Street BT2 7FW Belfast United Kingdom (Northern Ireland)
- TRADEPARENCY, 47bis rue des vinaigriers 75010 Paris None France
- Turbine Surface Technologies Limited, Rolls-Royce plc Moor Lane DE24 8BJ Derby Derbyshire United Kingdom
- Uni-Chem Sp. z o.o., Okopowa 56 / 81 01-042 Warsaw Poland
- VENATOR MATERIALS UK LIMITED, Titanium House Hanzard Drive TS22 5FD Wynyard Park United Kingdom
- VINICOLA DEL OESTE, S.A., Avda. Márquez Escobar, 83 06220 Villafranca de los Barros Badajoz Spain
- Vivergo Fuels, c/o Shoosmiths Secretaries Ltd. Witan Gate House, 500-600 Witan Gate West MK9 1SH Milton Keynes Buckinghamshire United Kingdom
- Wielkopolskie Zaklady Farmacutyczna "bio-win" S.A., Polna 21 62-095 Murowana Goslina Wielkopolskie Poland
- Z.P.H.U. EDBAR Bartosz Wawrzyniak, Szczepice 34 89-240 Kcynia Poland Poland
- ZAKŁAD ROLNO-PRZEMYSŁOWY JANUSZ DOLIŃSKI, Kramarzewo 1 13-214 Uzdowo Warmińsko-mazurskie Poland
- Zakład Rolny Buczek S. C., Wielki Buczek 19A 63-630 Rychtal Poland
- Zakład Rolny KIJE Sp.z o.o., Kije 143 66-100 Sulechów Poland Poland
- ZEVAR, s.r.o., Vetrny Jenikov 147 58842 Vetrny Jenikov Czech Republic
- Škrobárny Pelhřimov, a.s., Křemešnická 818 39601 Pelhřimov Czech Republic
- [Confidential], [Confidential]
Substance names and other identifiers
This section displays all the public names and other identifiers available in ECHA's databases for the substance.
Regulatory process names gives the names under which the substance appears in ECHA's regulatory processes and lists.
Translated names gives the names in different EU languages, where available to ECHA. Note that translated names are available at this time only for substances which have a harmonised C&L or which are approved Biocidal active substances.
CAS names gives the name(s) provided to ECHA by the Chemical Abstracts Service, a division of the American Chemical Society, where available.
IUPAC names gives all the non-confidential names provided to ECHA in submissions under REACH, CLP, BPR and PIC, where indicated to be a IUPAC name. Note that this does not mean that they are properly structured names according to the IUPAC nomenclature. 'IUPAC name' is the generic field by which substance names are provided in various data submission tools. Therefore the quality of these names may be variable.
Trade names gives all public trade names submitted to ECHA in REACH registrations.
Other names gives any names of any other type, such as common names, synonyms and acronyms.
Other identifiers gives any other non-name identifiers available for ths substance. For example CLH index numbers, CN numbers, deleted CAS numbers, etc.
The data presented in these sections has been cleaned to remove names of one character or less, or names which consist solely of punctuation or numerical characters.
Scientific properties
This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.
Appearance/physical state / colour
This section summarises appearance, physical state and colour property values from all registered dossiers held in the ECHA database for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
If more than one value is available, results are displayed as concatenated distinct values, ordered from most to least commonly provided, with the percentage of provided values appended. The percentage is based on the count of values provided.
Physical state
For substance’s physical state at 20°C and 1 013 hPa, registrants can classify their substance as:
- Solid
- Liquid
- Gaseous
Form
For substance’s form, registrants can classify their substance as:
- Aerosol dispenser: not specified
- Aerosol dispenser: foam aerosol
- Aerosol dispenser: spray aerosol
- Gas
- Gas: vapour
- Gas under pressure: compressed gas
- Gas under pressure: dissolved gas
- Gas under pressure: liquefied gas
- Gas under pressure: refrigerated liquefied gas
- Liquid
- Liquid: viscous
- Liquid: volatile
- Liquid – liquid: emulsion
- Liquid – solid: mixture of
- Semi–solid (amorphous): gel
- Solid
- Solid: bulk
- Solid: compact
- Solid: crystalline
- Solid: fibres
- Solid: filaments
- Solid: flakes
- Solid: granular
- Solid: pellets
- Solid: particulate/powder
- Solid: nanomaterial, surface–treated
- Solid: nanomaterial, no surface treatment
- Solid: nanomaterial
- Solid – liquid: aqueous solution
- Solid – liquid: suspension
- Solid – solid: alloy
- Aerosol
- Compact
- Crystalline
- Dispersion
- Fibre
- Filaments
- Flakes
- Liquefied gas
- Nanomaterial
- Particulates
- Paste
- Pellets
- Powder
- Refrigerated liquid
- Suspension
- Viscous
- Other
- No data
Odour
For substance’s odour, registrants can classify their substance as:
- Ammonia-like
- Biting
- Characteristic of sulphur containing compounds
- Characteristic of aromatic compounds
- Faint
- Garlic-like
- Odourless
- Pungent
- Slight
- Sweetish
- Other
Type
For substance’s type, registrants can classify their substance as:
- Element
- Inorganic
- Natural substance
- Organic
- Organometallic
- Petroleum product
- Other
Summary
Summary data is collected from the endpoint summary(ies) provided by registrants of REACH dossiers.
Physical state at 20°C and 1013 hPa
For substance’s physical state at 20°C and 1013 hPa, registrants can classify their substance as:
- Solid
- Liquid
- Gaseous
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data–waving justifications.
Study results
- 7 studies submitted
- 4 studies processed
- C Physical state at 20°C and 1013 hPa
- Liquid (100%) [4]
- C Form
- Other (100%) [2]
- C Odour
- Other (75%), Pungent (25%) [4]
- C Substance type
- Organic (100%) [4]
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | 4 | |||
Supporting study | 3 | |||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
no waivers |
C Summaries
- 3 summaries submitted
- 3 summaries processed
- Physical state at 20°C and 1013 hPa
- Liquid (100%)
Melting/freezing point
This section summarises the melting and freezing point values from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’.
Study results
If more than one numerical result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method).
Melting / freezing point provides substance information on the melting/freezing point in °C at a pressure measured in Pa.
Results without measurement conditions (pressure) are not processed for the Brief Profile. Additionally, if registrants select ‘other’ as a unit of measure for pressure, the measurement conditions (and therefore the study results) cannot be processed in the Brief Profile.
Summary
Melting/freezing point at 101 325 Pa provides information on the substance melting/freezing point in °C at a pressure of 101 325 Pa.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data–waving justifications.
Study results
- 11 studies submitted
- 5 studies processed
- R Melting / freezing point
- -114.49 - -97.8 °C @ 101.325 kPa [5]
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | 4 | 1 | ||
Supporting study | 3 | 3 | ||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
no waivers |
R Summaries
- 5 summaries submitted
- 4 summaries processed
- Melting / freezing point at 101 325 Pa
- -123.37 - -114 °C
Boiling point
This section summarises the boiling point values from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header .
Study results
If more than one numerical result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method).
Relative density provides substance information on the relatively density (measurement units are not processed for relative density) at a temperature measured in Celsius (°C).
Bulk density provides substance information on the bulk density in (kilo)grams per (centi)metre (cm/m) at a temperature measured in °C.
Density provides substance information on the density in grams per (centi)metre at a temperature measured in °C.
Pour density provides substance information on the pour density in grams per millilitre at a temperature measured in °C.
Tap density provides substance information on the bulk density per grams per millilitre at a temperature measured in °C.
Note: Registrants can also select ‘other’ as the type of density. If so, the data provided is not processed for the Brief Profile.
Summary
Relative density at 20 °C provides information on the substance relative density at 20 °C. If more than one value is found for this section, the range of min-max values will be displayed here.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data-waving justifications.
Study results
- 10 studies submitted
- 4 studies processed
- R Boiling point
- 64.7 - 78.29 °C @ 101.3 - 101.325 kPa [4]
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | 3 | 1 | ||
Supporting study | 1 | 5 | ||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
no waivers |
R Summaries
- 5 summaries submitted
- 4 summaries processed
- Boiling point at 101 325 Pa
- 20.1 - 78.293 °C
Density
This section summarises the density values from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
If more than one numerical result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method).
Relative density provides substance information on the relatively density (measurement units are not processed for relative density) at a temperature measured in Celsius (°C).
Bulk density provides substance information on the bulk density in (kilo)grams per (centi)metre (cm/m) at a temperature measured in °C.
Density provides substance information on the density in grams per (centi)metre at a temperature measured in °C.
Pour density provides substance information on the pour density in grams per millilitre at a temperature measured in °C.
Tap density provides substance information on the bulk density per grams per millilitre at a temperature measured in °C.
Note: Registrants can also select ‘other’ as the type of density. If so, the data provided is not processed for the Brief Profile.
Summary
Relative density at 20 °C provides information on the substance relative density at 20 °C. If more than one value is found for this section, the range of min-max values will be displayed here.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 11 studies submitted
- 5 studies processed
- R Bulk density
- 0.785 - 0.789 g/cm³ @ 20 - 25 °C [3]
- R Density
- 0.786 g/cm³ @ 25 °C [2]
- R Relative density
- 0.79 - 0.8 @ 20 °C [1]
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | 4 | 1 | ||
Supporting study | 2 | 4 | ||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
no waivers |
R Summaries
- 4 summaries submitted
- 3 summaries processed
- Relative density at 20°C
- 0.789 - 0.789
Vapour pressure
This section summarises the vapour pressure values from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
If more than one numerical result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method).
Vapour pressure provides substance information on the vapour pressure in Pa at a temperature measured in °C.
Note: Registrants can also select ‘other’ as the unit of measure for pressure. If so, the pressure data provided is not processed for the Brief Profile.
Summary
Vapour pressure provides substance information on the vapour pressure in Pa at a temperature measured in °C.
Type of study provided
This section provides an overview of the type of study records behind the presented results and data waving justifications.
Study results
- 15 studies submitted
- 5 studies processed
- R Vapour pressure
- 57.26 - 169.27 hPa @ 19.6 - 25 °C [5]
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | 4 | 1 | ||
Supporting study | 3 | 7 | ||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
no waivers |
R Summaries
- 5 summaries submitted
- 4 summaries processed
- Vapour pressure
- 57.26 - 1 200 hPa @ 19.6 - 25 °C
Partition coefficient
This section summarises the partition coefficient values from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
If more than one numerical result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method).
Pow provides substance information on the partition coefficient type Pow at a temperature measured in °C and acidity in pH.
Log Pow provides substance information on the partition coefficient type Pow at a temperature measured in °C and acidity in pH.
Summary
Log Pow (Log Kow) provides substance information on the partition coefficient type Log Pow (Log Kow) at a temperature measured in °C.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications
Study results
- 12 studies submitted
- 5 studies processed
- R Log Pow
- -0.77 - -0.3 @ 24 - 25 °C and pH 7 - 7.4 [5]
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | 4 | 1 | ||
Supporting study | 2 | 5 | ||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
no waivers |
R Summaries
- 5 summaries submitted
- 4 summaries processed
- Log Kow (Log Pow)
- -0.35 - 0.45 @ 20 - 25 °C
Water solubility
This section summarises the water solubility values from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
If more than one numerical result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method).
Water solubility provides substance information on the substance’s solubility in water in grams per litre at a temperature measured in °C. Values provided in ppb and Vol% are provided separately.
Summary
Water solubility provides substance information on the substance’s solubility in water in grams per litre at a temperature measured in °C.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 9 studies submitted
- 4 studies processed
- R Water solubility (mass/vol.)
- 789 - 1 000 g/L @ 20 °C and pH 7 [4]
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | 4 | |||
Supporting study | 1 | 4 | ||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
no waivers |
R Summaries
- 4 summaries submitted
- 2 summaries processed
- Water solubility
- 789 g/L @ 20 °C
Solubility in organic solvents / fat solubility
Study results
If more than one result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method).
Solubility provides substance information on the substance’s solubility in organic solvents/fat in grams per litre at a temperature measured in °C. Registrants can provide data for one or more of the following picklist options:
- Standard fat
- Acetone
- Acetonitrile
- Benzene
- N-butanol
- Cyclohexane
- Diethyl ether
- Diethyl ketone
- Dimethylformamide
- DMSO, ethanol
- Ethyl acetate
- Isopropanol
- Methanol
- N-octanol
- Toluene
Note: Registrants can also select ‘other’ as the solvent. If so, the data provided is not processed for the Brief Profile.
Also, if the registrant selects the ‘mg/100 g solvent’; ‘g/kg solvent’; ‘ppb’; ‘vol%’ and ‘other’ as a unit of measure, the data provided will not be processed for the Brief Profile.
Summary
Solubility in mg/100g standard fat at 20°C provides substance information on the substance solubility in standard fat in milligram per 100 gram at a temperature of 20°C.
Solubility in organic solvents at 20°C provides substance information on the substance solubility in organic solvents in gram per litre at a temperature of 20°C.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Data not provided by the registrant
Surface tension
This section summarises the surface tension values from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
If more than one result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method).
Surface tension provides substance information on the surface tension in (milli)Newton per metre in a concentration in (milli)gram per metre and at a temperature measured in °C.
Note: Results without a concentration value are not processed for the Brief Profile.
Also, if the registrant selects ‘ppb’; ‘vol%’ and ‘other’ as a unit of measure for the concentration value, the data provided will not be processed for the Brief Profile.
Summary
Surface tension at 20°C provides substance information on the surface tension in (milli)Newton per metre in a concentration in (milli)gram per metre, at a temperature of 20 °C.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 5 studies submitted
- 0 studies processed
No automatically processable data submitted
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | 3 | |||
Supporting study | 1 | |||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
Not feasible | |
Sci. unjustified | |
Exposure cons. | |
Other | 1 |
Summaries
- 3 summaries submitted
- 0 summaries processed
No automatically processable data submitted
Flash point
This section summarises the flash point values from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
If more than one result is available per endpoint, the range of results (min-max, RANGE method) will be presented.
Flash point provides substance information on the substance’s flash point at a temperature measured in °C at a pressure measured in Pascal.
Summary
Flash point at 101 325 Pa provides substance information on the substance’s flash point at a temperature measured in °C at a pressure of 101 325 Pascal.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 7 studies submitted
- 4 studies processed
- R Flash point
- 9.7 - 13 °C @ 101.3 - 101.325 kPa [4]
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | 2 | |||
Supporting study | 1 | |||
Weight of evidence | 4 | |||
Other |
Data waiving | |
---|---|
no waivers |
R Summaries
- 3 summaries submitted
- 2 summaries processed
- Flash point at 101 325 Pa
- 12.85 - 13 °C
Auto flammability
This section summarises the auto flammability values from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
If more than one result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method).
Autoflammability / Self-ignition provides substance information on the substance’s self-ignition temperature in °C at a pressure measured in Pascal.
Note: Registrants can also select ‘other’ as the unit of measure for pressure. If so, the pressure data provided is not processed for the Brief Profile.
Summary
Autoflammability / Self-ignition at 101 325 Pa provides substance information on the substance’s self-ignition temperature in °C at a pressure of 101 325 Pa.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 10 studies submitted
- 4 studies processed
- R Autoflammability / self-ignition
- 363 - 455 °C @ 101.3 - 101.325 kPa [4]
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | 1 | 3 | ||
Supporting study | 6 | |||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
no waivers |
R Summaries
- 3 summaries submitted
- 2 summaries processed
- Autoflammability / self-ignition at 101 325 Pa
- 362.85 - 368.8 °C
Flammability
This section summarises the flammability values from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
If more than one value is available, results are displayed as concatenated distinct values, ordered by most to least commonly provided, with the % of provided values appended. The % is based on count of values provided.
Applicant’s summary and conclusion – Interpretation of results. Registrants can register their substance flammability as:
- Extremely flammable aerosols (Cat. 1)
- Flammable gases (Cat.1)
- Flammable solids (Cat.1)
- Pyrophoric liquids (Cat.1)
- Pyrophoric solids (Cat. 1)
- Self-heating substances and mixtures (Cat. 1)
- Substances or mixtures which in contact with water release flammable gases which may ignite spontaneously (Cat.1)
- Flammable aerosols (Cat.2)
- Flammable gases (Cat.2)
- Flammable solids (Cat.2)
- Self-heating substances and mixtures (Cat.2)
- Substances or mixtures which in contact with water release flammable gases which may ignite spontaneously (Cat.2)
- Non-flammable aerosols (Cat.3)
- Substances or mixtures which in contact with water releases flammable gases (Cat.3)
- Chemically unstable gases (Cat.A)
- Chemically unstable gases (Cat.B)
- GHS criteria not met
- Not classified based on GHS criteria
- Extremely flammable
- Extremely flammable liquefied gas
- Substances and mixtures which in contact with water emit flammable gases
- Contact with water liberates highly flammable gases
- Highly flammable
- Flammable
- Pyrophoric
- Spontaneously flammable in air (pyrophoric)
- Non–flammable
- Non flammable (based on GHS criteria)
- No information available
- Not classified
Note: Registrants can also select ‘other’ as the flammability value for their substance. If so, the data provided is not processed for the Brief Profile.
Summary
Registrants can register their substance’s flammability as:
- Extremely flammable
- Extremely flammable liquefied gas
- Contact with water liberates highly flammable gases
- Highly flammable
- Flammable
- Spontaneously flammable in air (pyrophoric)
- Non–flammable
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 10 studies submitted
- 2 studies processed
- C Interpretation of results
- Highly flammable (100%) [2]
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | 2 | |||
Supporting study | 2 | 2 | ||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
Not feasible | |
Sci. unjustified | 3 |
Exposure cons. | |
Other | 1 |
C Summaries
- 4 summaries submitted
- 4 summaries processed
- Flammability
- Highly flammable (100%)
Explosiveness
This section summarises the explosiveness values from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
If more than one value is available, results are displayed as concatenated distinct values, ordered by most to least commonly provided, with the % of provided values appended. The % is based on count of values provided.
Applicant’s summary and conclusion – Interpretation of results. Registrants can register their substance explosiveness as:
- Unstable explosive
- Mass explosion hazard (Div. 1.1)
- Projection hazard but not a mass explosion hazard (Div. 1.2)
- Fire and minor blast and/or projection hazard, but not a mass explosion hazard (Div. 1.3)
- No significant hazard (Div. 1.4)
- Very insensitive substances with mass explosion hazard (Div. 1.5)
- Extremely insensitive which do not have a mass explosion hazard (Div. 1.6)
- GHS criteria not met
- Explosive
- Non explosive
Summary
Explosiveness. Registrants can register their substance explosiveness as:
- Explosive
- Non explosive
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 4 studies submitted
- 0 studies processed
No automatically processable data submitted
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | ||||
Supporting study | ||||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
Not feasible | |
Sci. unjustified | 2 |
Exposure cons. | |
Other | 2 |
C Summaries
- 2 summaries submitted
- 2 summaries processed
- Explosiveness
- Non-explosive (100%)
Oxidising
This section summarises the oxidising values from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
If more than one value is available, results are displayed as concatenated distinct values, ordered by most to least commonly provided, with the % of provided values appended. The % is based on count of values provided.
Applicant’s summary and conclusion – Interpretation of results. Registrants can register their substance’s oxidising properties as:
- no oxidising properties
- oxidising: maximum burning rate equal or higher than reference mixture
- oxidising: vigorous reaction in preliminary test
- oxidising;
- test not applicable because organic peroxide.
Note: Registrants can also select ‘other’ as the oxidising value for their substance. If so, the data provided is not processed for the Brief Profile.
Summary
Oxidising. Registrants can register their substance oxidising properties as:
- Oxidising
- Yes
- Non oxidising
- No
- No information available
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 4 studies submitted
- 0 studies processed
No automatically processable data submitted
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | ||||
Supporting study | ||||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
Not feasible | 1 |
Sci. unjustified | 1 |
Exposure cons. | |
Other | 2 |
C Summaries
- 2 summaries submitted
- 2 summaries processed
- Oxidising
- No (100%)
Oxidation reduction potential
This section summarises the oxidation reduction potential values from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
If more than one numerical result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method).
Oxidation reduction potential in mV provides substance information on the substance’s oxidation reduction measured in millivolts at a temperature measured in °C.
Summary
Oxidation reduction potential in mV at 20°C provides substance information on the substance’s oxidation reduction measured in millivolts at a temperature of 20°C.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Data not provided by the registrant
pH
This section summarises the pH values from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
If more than one numerical result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method).
pH provides substance information on the substance’s acidity level measured in pH at a temperature measured in °C and a concentration measured in (milli)grams per litre.
Note: Results without a concentration value are not processed for the Brief Profile.
Summary
For this endpoint registrants do not provide summary data.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Data not provided by the registrant
Dissociation constant
This section summarises the dissociating values from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
If more than one picklist value is available per endpoint, results are displayed as concatenated distinct values, ordered by most to least commonly provided, with the % of provided values appended. The % is based on count of values provided.
If more than one numerical result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method).
Dissociating Properties provides substance information by picklist values:
- Yes
- No
- Ambiguous
- Not determined
Dissociation Constant provides numerical substance information on the substance’s dissociation constant values at a temperature measured in °C.
Summary
pKa at 20°C provides numerical substance information on the dissociation constant in pKa at a temperature of 20°C.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 5 studies submitted
- 3 studies processed
- C Dissociating properties
- Not determined (100%) [3]
- R Dissociation constant
- 15.9 @ 20 °C [3]
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | 3 | |||
Supporting study | 1 | |||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
Not feasible | |
Sci. unjustified | 1 |
Exposure cons. | |
Other |
R Summaries
- 3 summaries submitted
- 1 summary processed
- pKa at 20 °C
- 15.8
Viscosity
This section summarises the viscosity values from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
If more than one numerical result is available per endpoint, the range of results (min–max) and range of experimental conditions will be presented (RANGE method).
Registrants can report substance information on viscosity as:
- Dynamic viscosity (in mPa s)
- Kinematic viscosity (in mm²)/s)
- Flow time (in s) – ASTM Cup 1
- Flow time (in s) – ASTM Cup 2
- Flow time (in s) – ASTM Cup 3
- Flow time (in s) – ASTM Cup 4
- Flow time (in s) – 3 mm ISO cup
- Flow time (in s) – 4 mm ISO cup
- Flow time (in s) – 5 mm ISO cup
- Flow time (in s) – 6 mm ISO cup
- Flow time (in s) – other:
Summary
Static viscosity at 20°C provides substance information on the substance’s (static) viscosity per square millimetre per second at a temperature of 20°C.
Dynamic viscosity at 20°C provides substance information on the substance’s (dynamic) viscosity per millipascal second at a temperature of 20°C.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 8 studies submitted
- 7 studies processed
- R dynamic viscosity (in mPa s)
- 0.544 - 1.22 [6]
- R kinematic viscosity (in mm²/s)
- 1.082 - 2.247 [5]
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | 2 | |||
Supporting study | 1 | |||
Weight of evidence | 1 | 4 | ||
Other |
Data waiving | |
---|---|
no waivers |
R Summaries
- 3 summaries submitted
- 2 summaries processed
- Dynamic viscosity at 20 °C
- 1.17 - 1.2 mPa.s
This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.
Phototransformation in air
This section summarises the values related to phototransformation in air from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
If more than one numerical result is available per endpoint, the range of results (min-max, RANGE method) will be displayed.
Dissipation half-life provides substance information on the substance’s dissipation half-life for the parent compound per second/minute/hour/day/week/month/year.
Degradation rate constant (OH Radicals) provides substance information on the substance’s degradation rate constant with OH Radicals as a reaction type in cm3molecule-1s-1, cm3molecule-1d-1, m3molecule-1s-1 or m3molecule-1d-1.
Degradation rate constant (Ozone) provides substance information on the substance’s degradation rate constant with Ozone as a reaction type in cm3molecule-1s-1, cm3molecule-1d-1, m3molecule-1s-1 or m3molecule-1d-1.
Note: Registrants can also select ‘other’ as a reaction type for the degradation rate constant of the substance. If so, the data provided is not processed in the Brief Profile.
Summary
Half-life in air provides substance information on the substance’s dissipation half-life in air in seconds/minutes/hours/days/weeks/months/years.
Degradation rate constant with OH radicals provides substance information on the substance’s degradation rate constant with OH Radicals as a reaction type in cm3molecule-1s-1, cm3molecule-1d-1, m3molecule-1s-1 or m3molecule-1d-1.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 14 studies submitted
- 4 studies processed
- R Dissipation half life (DT50)
- 2.8 - 13.8 h [8]
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | ||||
Supporting study | 4 | 4 | ||
Weight of evidence | 6 | |||
Other |
Data waiving | |
---|---|
no waivers |
R Summaries
- 2 summaries submitted
- 1 summary processed
- Half life in air
- 38 h
Hydrolysis
This section summarises the values related to hydrolysis from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
For this endpoint registrants do not provide study results that are processable for the Brief Profile.
Summary
Half-life for hydrolysis provides substance information on the substance’s half-life for hydrolysis in seconds/minutes/hours/days/weeks/months/years at a temperature measured in °C.
Note: Results without a measurement condition (temperature) are not processed for the Brief Profile.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 6 studies submitted
- 0 studies processed
Study data not processed for brief profile
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | ||||
Supporting study | 2 | |||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
Not feasible | |
Sci. unjustified | 3 |
Exposure cons. | |
Other | 1 |
Summaries
- 3 summaries submitted
- 0 summaries processed
No automatically processable data submitted
Phototransformation in water
This section summarises the values related to phototransformation in water from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
If more than one numerical result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method).
Dissipation Half-life of parent compound provides substance information on the substance’s dissipation half-life for the parent compound per second/minute/hour/day/week/month/year.
Summary
Phototransformation in water provides information on the substance’s phototransformation in water in seconds/minutes/hours/days/weeks/months/years.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Data not provided by the registrant
Phototransformation in soil
This section summarises the values related to phototransformation in soil from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
If more than one numerical result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method).
Dissipation Half-life of parent compound provides substance information on the substance’s dissipation half-life for the parent compound per second/minute/hour/day/week/month/year.
Summary
Phototransformation in soil provides substance information on the substance’s phototransformation in soil in seconds/minutes/hours/days/weeks/months/years.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Data not provided by the registrant
Biodegradation in water - screening tests
This section summarises the values related to the screening tests for biodegradation in water from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
If more than one numerical result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method).
If more than one picklist value is available per endpoint, results are displayed as concatenated distinct values, ordered by most to least commonly provided, with the % of provided values appended. The % is based on count of values provided.
BOD5 provides substance information on the substance’s BOD5 values displayed in O2 (milli)gram per gram test material.
COD provides substance information on the substance’s COD values displayed in O2 (milli)gram per gram test material.
BOD5*100/COD provides substance information on the substance’s BOD5*100/COD values displayed in O2 (milli)gram per gram test material.
BOD5/COD ratio provides substance information on the substance’s BOD5/COD ratio values displayed in O2 (milli)gram per gram test material.
BOD5/ThOD ratio provides substance information on the substance’s BOD5/ThOD ratio values displayed in O2 (milli)gram per gram test material.
BOD5*100/ThOD provides substance information on the substance’s BOD5*100/ThOD values displayed in O2 (milli)gram per gram test material.
ThOD provides substance information on the substance’s ThOD values displayed in O2 (milli)gram per gram test material.
Note: Registrants can also select ‘other’ as the unit of measure. If so, the data provided is not processed for the Brief Profile.
Applicant’s summary and conclusion – Interpretation of results provides information on the substance’s biodegradation properties in water and can be registered by the registrants by one or more of the following picklist options:
- Readily biodegradable
- Readily biodegradable but failing the 10-day window
- Inherently biodegradable
- Inherently biodegradable, fulfilling specific criteria;
- Inherently biodegradable, not fulfilling specific criteria
- Not inherently biodegradable
- Not readily biodegradable
- Under test conditions no biodegradation observed
Note: Registrants can also select ‘other’ as picklist option for describing the biodegradation values of the substance in water. If so, the data provided is not processed in the Brief Profile.
Summary
Biodegradation in water provides information on the substance’s biodegradation properties in water and can be registered by the registrants by one or more of the following picklist options:
- Readily biodegradable
- Readily biodegradable but failing the 10-day window
- Inherently biodegradable
- Inherently biodegradable, fulfilling specific criteria;
- Inherently biodegradable, not fulfilling specific criteria
- Under test conditions no biodegradation observed
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 24 studies submitted
- 7 studies processed
- R BOD5
- 1.067 - 1.236 g O2/g test material [2]
- R COD
- 1.99 g O2/g test material [3]
- C Interpretation of results
- Readily biodegradable (100%) [7]
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | 3 | 4 | ||
Supporting study | 11 | 1 | 5 | |
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
no waivers |
C Summaries
- 3 summaries submitted
- 3 summaries processed
- Biodegradation in water
- Readily biodegradable (100%)
Biodegradation in water & sediment - simulation tests
This section summarises the values related to the simulation tests for biodegradation in water and sediments from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
For this endpoint registrants do not provide study results that are processable for the Brief Profile.
Summary data
If more than one numerical result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method).
Half-life in water provides substance information on the substance’s half-life in water in seconds/minutes/hours/days/weeks/months/years at a temperature measured in °C.
Note: If a temperature value is not provided by the registrant, the information on half-life in water will not be processed for the Brief Profiles.
Half-life in sediment provides substance information on the substance’s half-life in sediment in seconds/minutes/hours/days/weeks/months/years at a temperature measured in °C.
Note: Results without a measurement condition (temperature) are not processed for the Brief Profile.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 0 studies submitted
- 0 studies processed
Study data not processed for brief profile
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | ||||
Supporting study | ||||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
no waivers |
Summaries
- 1 summary submitted
- 0 summaries processed
No automatically processable data submitted
Biodegradation in soil
This section summarises the values related to biodegradation in soil from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
For this endpoint registrants do not provide study results that are processable for the Brief Profile.
Summary data
If more than one numerical result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method).
Half-life in soil provides substance information on the substance’s half-life in water in seconds/minutes/hours/days/weeks/months/years at a temperature measured in °C.
Note: Results without a measurement condition (temperature) are not processed for the Brief Profile.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 6 studies submitted
- 0 studies processed
Study data not processed for brief profile
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | ||||
Supporting study | 1 | 1 | ||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
Not feasible | |
Sci. unjustified | 3 |
Exposure cons. | |
Other | 1 |
Summaries
- 1 summary submitted
- 0 summaries processed
No automatically processable data submitted
Bioaccumulation: aquatic / sediment
This section summarises the values related to aquatic/sediment bioaccumulation in all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
For this endpoint registrants do not provide study results that are processable for the Brief Profile.
Summary data
If more than one numerical result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method).
Bioaccumulation factor (aquatic species) provides substance information on the substance’s bioaccumulative properties not taking account the dimensions.
Bioaccumulation Factor (aquatic species) L/kg ww provides substance information on the substance’s bioaccumulative properties for aquatic species measured in litre per kilogram (wet weight).
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 7 studies submitted
- 0 studies processed
Study data not processed for brief profile
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | ||||
Supporting study | 2 | |||
Weight of evidence | ||||
Other | 1 |
Data waiving | |
---|---|
Not feasible | |
Sci. unjustified | 2 |
Exposure cons. | |
Other | 2 |
Summaries
- 1 summary submitted
- 0 summaries processed
No automatically processable data submitted
Bioaccumulation: terrestrial
This section summarises the values related to terrestrial bioaccumulation in all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
For this endpoint registrants do not provide study results that are processable for the Brief Profile.
Summary data
If more than one numerical result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method).
Bioaccumulation factor (terrestrial species) provides substance information on the substance’s terrestrial bioaccumulative properties not taking account the dimensions.
Bioaccumulation Factor (terrestrial species) L/kg ww provides substance information on the substance’s terrestrial bioaccumulative properties measured in litre per kilogram (wet weight).
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Data not provided by the registrant
Adsorption/desorption
This section summarises the values related to adsorption/desorption from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
If more than one numerical result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method).
Koc provides substance information on the substance’s Koc adsorption at a temperature measured in °C and a percentage of organic carbon.
Log Koc provides substance information on the substance’s Koc adsorption at a temperature measured in °C and a percentage of organic carbon.
Kd provides substance information on the substance’s Koc adsorption at a temperature measured in °C and a percentage of organic carbon.
Log Kd provides substance information on the substance’s Koc adsorption at a temperature measured in °C and a percentage of organic carbon.
Note: If the measurement condition (percentage of organic carbon) is not provided by the registrant for adsorption coefficient Kd, the data provided is not processed for the Brief Profile.
Summary
Koc at 20°C provides substance information on the substance’s Koc adsorption at a temperature 20 °C.
Log Koc at 20°C provides substance information on the substance’s log Koc adsorption at a temperature 20 °C.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 7 studies submitted
- 0 studies processed
No automatically processable data submitted
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | ||||
Supporting study | 1 | 2 | ||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
Not feasible | |
Sci. unjustified | 2 |
Exposure cons. | |
Other | 2 |
Summaries
- 1 summary submitted
- 0 summaries processed
No automatically processable data submitted
Henrys law constant (H)
This section summarises the values related to Henry’s law constant (H) from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
If more than one numerical result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method).
Henry’s law constant can be presented as different types, depending on the units chosen:
H dimensionless provides substance information on the substance’s Henry’s Law Constant (dimensionless) at a temperature measured in °C and a pressure measured in Pascal.
H dimensionless volumetric basis provides substance information on the substance’s Henry’s Law Constant in dimensionless volumetric basis at a temperature measured in °C and a pressure measured in Pascal.
H atm provides substance information on the substance’s Henry’s Law Constant in atm at temperature measured in °C and a pressure measured in Pascal.
H atm m3/mol provides substance information on the substance’s Henry’s Law Constant in atm m3/mol at a temperature measured in °C and a pressure measured in Pascal.
H Pa m3/mol provides substance information on the substance’s Henry’s Law Constant in Pa m3/mol at a temperature measured in °C and the atmospheric pressure measured in Pascal.
Note: Registrants can also select ‘other’ as the type of Henry’s law constant. If so, the data provided is not processed for the Brief Profile.
Summary
Henry’s Law Constant provides substance information on the substance’s Henry’s Law Constant measured in in Pa.m3.mol-1 at a temperature measured in °C.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 1 study submitted
- 0 studies processed
No automatically processable data submitted
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | ||||
Supporting study | 1 | |||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
no waivers |
Summaries
- 1 summary submitted
- 0 summaries processed
No automatically processable data submitted
Distribution modelling
This section summarises the values related to distribution modelling from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
Displayed are the RANGES of min – max of values (provided in %).
Percentage distribution in the Media displays the values attributed by the registrants to the following options:
- air
- water
- soil
- sediment
- suspended sediment
- biota
- aerosol
Summary
For this endpoint registrants do not provide summaries that are processable for the Brief Profile.Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 2 studies submitted
- 2 studies processed
- % Distribution in Media:
R Air | 12.5 - 73.3 % [2] |
R Water | 15.6 - 87.5 % [2] |
R Soil | 0 - 11.1 % [2] |
R Sediment | 0 - 0.02 % [2] |
R Suspended sediment | 0 % [1] |
R Biota | 0 % [1] |
R Aerosol | 0 % [1] |
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | 2 | |||
Supporting study | ||||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
no waivers |
No summary exists for this scientific endpoint
This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.
Predicted No-Effect Concentration (PNEC)
If more than one numerical result is available per endpoint, the range of results (min-max) will be presented (RANGE method).
Hazard to aquatic organisms provides information on the substance’s hazard assessment conclusion regarding aquatic organisms.
Manufacturers and importers can provide the following information in the registration dossier:
Freshwater/marine water/intermittent:
- PNEC aqua, displayed in milligram per litre.
- No data: aquatic toxicity unlikely
- No data available: testing technically not feasible
- No hazard identified
Sewage treatment plant (STP)
- PNEC STP, data displayed in milligram per litre.
- No data: aquatic toxicity unlikely
- No data available: testing technically not feasible
- No emission the STP expected
- No hazard identified
Sediment freshwater/marine water
- PNEC sediment, data displayed in milligram per kilo sediment (dry weight).
- No or insufficient data available at present
- No exposure of sediment expected
- No data available: testing technically not feasible
- No hazard identified
Hazard for Air provides information on the substance’s hazard assessment conclusion related to air.
Data is generally standardised and displayed in milligram per litre/cubic metre.
Manufacturers and importers can provide the following information in the registration dossier:
- PNEC air
- Hazard related to composition of atmosphere identified
- No hazard identified
Hazard for terrestrial organisms provides information on the substance’s hazard assessment conclusion related to terrestrial organisms/soil.
Data is generally standardised and displayed in milligram per kilo soil (dry weight).
Manufacturers and importers can provide the following information in the registration dossier:
- PNEC soil
- No or insufficient data available at present
- No exposure of soil expected
- No data available: testing technically not feasible
- No hazard identified
Hazard for predators provides information on the substance’s hazard assessment conclusion related to predators/secondary poisoning.
Data is generally standardised and displayed in in milligram per kilo of food.
Manufacturers and importers can provide the following information in the registration dossier:
- PNEC oral
- No potential for bioaccumulation
- No potential to cause toxic effects if accumulated (in higher organisms) via the food chain
- No or insufficient data available at present
- No data available: testing technically not feasible
R Summaries
- 4 summaries submitted
- 4 summaries processed
The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.
Hazard for Aquatic Organisms | |
---|---|
Freshwater | 960 µg/L (4) |
Intermittent releases (freshwater) | 2.75 mg/L (4) |
Marine water | 790 µg/L (4) |
Intermittent releases (marine water) | - |
Sewage treatment plant (STP) | 580 mg/L (4) |
Sediment (freshwater) | 3.6 mg/kg sediment dw (4) |
Sediment (marine water) | 2.9 mg/kg sediment dw (3) |
Hazard for Air | |
---|---|
Air | No hazard identified (3) |
Hazard for Terrestrial Organism | |
Soil | 630 µg/kg soil dw (4) |
Hazard for Predators | |
Secondary poisoning | 380 - 720 mg/kg food (3) |
Short–term toxicity to fish
This section summarises the values related to short–term toxicity to fish from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. Data is generally standardised and displayed in milligram per litre or molar per litre.
The availability of additional data beyond the five results displayed is indicated by (…).
Processable data is prioritised by the toxicity descriptor type (see list below) and subsequently further prioritised by duration (longer prioritised over shorter). The five highest priority groupings of provided data are displayed in milligram per litre or molar per litre.
Prioritisation by dose descriptor:
- LC50
- LC0
- LC100
- LC10
- EC50
- EC0
- EC100
- EC10
- NOEC
- LOEC
- LL50
- LL0
- LL100
- LL10
- EL50
- EL0
- EL100
- EL10
- IC50
- IC10
- IC100
- NOELR
- LOELR
Note: Registrants can also select ‘other’ as the dose descriptor type or unit of measure. If so, the data provided is not processed for the Brief Profile.
Summary
LC50 for freshwater fish provides substance information on the substance’s lethal concentration for 50% of the freshwater fish in the test, displayed in milligram per litre.
LC50 for marine water fish provides substance information on the substance’s lethal concentration for 50% of the marine water fish in the test, displayed in milligram per litre.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 30 studies submitted
- 6 studies processed
- P/RResults
- LC50 (4 days) 14.2 - 15.4 g/L [6]
- LC0 (4 days) 7.96 g/L [1]
- EC50 (4 days) 12.7 - 12.9 g/L [3]
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | 5 | 1 | ||
Supporting study | 16 | 8 | ||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
no waivers |
Summaries
- 3 summaries submitted
- 0 summaries processed
No automatically processable data submitted
Long–term toxicity to fish
This section summarises the values related to long term toxicity to fish from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. Data is generally standardised and displayed in milligram per litre or molar per litre.
The availability of additional data beyond the five results displayed is indicated by (…).
Processable data is prioritised by the toxicity descriptor type (see list below) and subsequently further prioritised by duration (longer prioritised over shorter).
Prioritisation by dose descriptor:
- NOEC
- LOEC
- EC10
- LC10
- IC10
- EC50
- LC50
- IC50
- EL10
- EL50
- LL10
- LL50
- NOELR
- LOELR
Note: Registrants can also select ‘other’ as the dose descriptor type or unit of measure. If so, the data provided is not processed for the Brief Profile.
Summary
EC10 / LC10 or NOEC for freshwater fish provides substance information on the substance’s effect concentration/lethal concentration for 10% of the tested freshwater fish or the no observed effect concentration. Values are displayed in milligram per litre.
EC10 / LC10 or NOEC for marine fish provides substance information on the substance’s effect concentration/lethal concentration for 10% of the tested freshwater fish or the no observed effect concentration. Values are displayed in milligram per litre.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 11 studies submitted
- 1 study processed
- P/RResults
- NOEC (5 days) 250 - 1 000 mg/L [2]
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | 1 | |||
Supporting study | 3 | 1 | 1 | |
Weight of evidence | ||||
Other | 2 |
Data waiving | |
---|---|
Not feasible | |
Sci. unjustified | 2 |
Exposure cons. | |
Other | 1 |
Summaries
- 2 summaries submitted
- 0 summaries processed
No automatically processable data submitted
Short–term toxicity to aquatic invertebrates
This section summarises the values related to short term toxicity to aquatic invertebrates from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. Data is generally standardised and displayed in milligram per litre or molar per litre.
The availability of additional data beyond the five results displayed is indicated by (…).
Processable data is prioritised by the toxicity descriptor type (see list below) and subsequently further prioritised by duration (longer prioritised over shorter).
Prioritisation by dose descriptor:
- EC50
- IC50
- LC50
- EC0
- LC0
- EC100
- LC100
- LC10
- EC10
- NOEC
- LOEC
- LL50
- LL0
- LL100
- LL10
- EL50
- EL0
- EL100
- EL10
- IC10
- IC100
- NOELR
- LOELR
Note: Registrants can also select ‘other’ as the dose descriptor type or unit of measure. If so, the data provided is not processed for the Brief Profile.
Summary
LC50 for freshwater invertebrates provides substance information on the substance’s lethal concentration for 50% of the freshwater invertebrates in the test, displayed in milligram per litre.
LC50 for marine water invertebrates provides substance information on the substance’s lethal concentration for 50% of the marine water invertebrates in the test, displayed in milligram per litre.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 53 studies submitted
- 4 studies processed
- P/RResults
- EC50 (48 h) 10 g/L [1]
- EC50 (24 h) 10 g/L [1]
- LC50 (48 h) 5.012 g/L [3]
- EC0 (48 h) 10 g/L [1]
- EC0 (24 h) 10 g/L [1]
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | 3 | 1 | ||
Supporting study | 44 | 5 | ||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
no waivers |
Summaries
- 3 summaries submitted
- 0 summaries processed
No automatically processable data submitted
Long–term toxicity to aquatic invertebrates
This section summarises the values related to long term toxicity to aquatic invertebrates from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. Data is generally standardised and displayed in milligram per litre or molar per litre.
The availability of additional data beyond the five results displayed is indicated by (…).
Processable data is prioritised by the toxicity descriptor type (see list below) and subsequently further prioritised by duration (longer prioritised over shorter).
Prioritisation by dose descriptor:
- NOEC
- LOEC
- EC10
- LC10
- IC10
- EC50
- LC50
- IC50
- EL10
- EL50
- LL10
- LL50
- NOELR
- LOELR
Note: Registrants can also select ‘other’ as the dose descriptor type or unit of measure. If so, the data provided is not processed for the Brief Profile.
Summary
EC10 / LC10 or NOEC for freshwater invertebrates provides substance information on the substance’s effect concentration/lethal concentration for 10% of the tested freshwater invertebrates or the no observed effect concentration for freshwater invertebrates. Values are presented in (nano/ micro/milli)gram per litre and/or (nano/ micro/milli)molar per litre.
EC10 / LC10 or NOEC for marine water invertebrates provides substance information on the substance’s effect concentration/lethal concentration for 10% of the tested marine water invertebrates or the no observed effect concentration for marine water invertebrates. Values are presented in (nano/ micro/milli)gram per litre and/or (nano/ micro/milli)molar per litre.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 20 studies submitted
- 3 studies processed
- P/RResults
- NOEC (10 days) 2 - 9.6 mg/L [2]
- NOEC (9 days) 9.6 mg/L [2]
- LC50 (10 days) 1.806 g/L [1]
- LC50 (9 days) 454 mg/L [2]
- LC50 (48 h) 9.248 g/L [2]
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | 3 | |||
Supporting study | 15 | |||
Weight of evidence | ||||
Other | 1 |
Data waiving | |
---|---|
Not feasible | |
Sci. unjustified | |
Exposure cons. | |
Other | 1 |
Summaries
- 3 summaries submitted
- 0 summaries processed
No automatically processable data submitted
Toxicity to aquatic algae and cyanobacteria
This section summarises the values related to toxicity to aquatic algae and cyanobacteria from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. Data is generally standardised and displayed in milligram per litre or molar per litre.
The availability of additional data beyond the five results displayed is indicated by (…).
Processable data is prioritised by the toxicity descriptor type (see list below) and subsequently further prioritised by duration (longer prioritised over shorter).
Prioritisation by dose descriptor:
- EC50
- IC50
- NOEC
- LOEC
- EC10
- IC10
- EC20
- EC5
- EC0
- EC100
- IC100
- EC90
- EL0
- EL5
- EL10
- EL20
- EL50
- EL90
- EL100
- NOELR
- LOELR
Note: Registrants can also select ‘other’ as the dose descriptor type or unit of measure. If so, the data provided is not processed for the Brief Profile.
Summary
LC50 for freshwater algae provides substance information on the substance’s lethal concentration for 50% of the freshwater algae in the test, displayed in generally milligram per litre.
LC50 for marine water algae provides substance information on the substance’s lethal concentration for 50% of the marine water algae in the test, generally displayed in milligram per litre.
EC10 / LC10 or NOEC for freshwater algae provides substance information on the substance’s effect concentration/lethal concentration for 10% of the tested freshwater algea or the no observed effect concentration for freshwater algae. Values are generally displayed in milligram per litre.
EC10 / LC10 or NOEC for marine water algae provides substance information on the substance’s effect concentration/lethal concentration for 10% of the tested marine water algae or the no observed effect concentration for marine water algae. Values are generally displayed in milligram per litre.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 57 studies submitted
- 4 studies processed
- P/RResults
- EC50 (4 days) 675 - 22 000 mg/L [4]
- EC50 (72 h) 275 mg/L [3]
- EC10 (4 days) 86 mg/L [3]
- EC10 (72 h) 11.5 mg/L [3]
- EC100 (72 h) 14.2 g/L [3]
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | 3 | 1 | ||
Supporting study | 42 | 3 | ||
Weight of evidence | ||||
Other | 8 |
Data waiving | |
---|---|
no waivers |
R Summaries
- 3 summaries submitted
- 3 summaries processed
- EC50 for freshwater algae
- 275 mg/L
- EC50 for marine water algae
- 1.9 - 1.97 g/L
- EC10 or NOEC for freshwater algae
- 11.5 mg/L
- EC10 or NOEC for marine water algae
- 1.58 g/L
Toxicity to aquatic plants other than algae
This section summarises the values related to toxicity to aquatic plants (other than algae) from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. Data is generally standardised and the displayed in milligram per litre or molar per litre.
The availability of additional data beyond the five results displayed is indicated by (…).
Processable data is prioritised by the toxicity descriptor type (see list below) and subsequently further prioritised by duration (longer prioritised over shorter).
Prioritisation by dose descriptor:
- EC50
- IC50
- NOEC
- LOEC
- EC10
- IC10
- EC20
- EC5
- EC0
- EC100
- IC100
- EC90
- EL0
- EL5
- EL10
- EL20
- EL50
- EL90
- EL100
- NOELR
- LOELR
Note: Registrants can also select ‘other’ as the dose descriptor type or unit of measure. If so, the data provided is not processed for the Brief Profile.
Summary
EC/LC50 for freshwater plants provides substance information on the substance’s effect concentration or lethal concentration for 50% of the freshwater plants in the test, generally displayed in milligram per litre.
EC50/LC50 for marine water plants provides substance information on the substance’s effect concentration or lethal concentration for 50% of the marine water algae in the test, generally displayed in milligram per litre.
EC10 / LC10 or NOEC for freshwater plants provides substance information on the substance’s effect concentration/lethal concentration for 10% of the tested freshwater plants or the no observed effect concentration for freshwater plants. Values are generally displayed in milligram per litre.
EC10 / LC10 or NOEC for marine water plants provides substance information on the substance’s effect concentration/lethal concentration for 10% of the tested marine water plants or the no observed effect concentration for marine water plants. Values are generally displayed in milligram per litre.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 11 studies submitted
- 2 studies processed
- P/RResults
- EC50 (7 days) 4.432 - 5.967 g/L [6]
- NOEC (7 days) 280 - 1 296 mg/L [6]
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | 2 | |||
Supporting study | 9 | |||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
no waivers |
R Summaries
- 2 summaries submitted
- 2 summaries processed
- EC50 for freshwater plants
- 4.432 g/L
- EC10 or NOEC for freshwater plants
- 280 mg/L
Toxicity to microorganisms
This section summarises the values related to toxicity to microorganisms from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. Data is generally displayed in milligram per litre or molar per litre.
The availability of additional data beyond the five results displayed is indicated by (…).
Processable data is prioritised by the toxicity descriptor type (see list below) and subsequently further prioritised by duration (longer prioritised over shorter).
Prioritisation by dose descriptor:
- EC50
- IC50
- NOEC
- LOEC
- EC10
- IC10
- EC0
- IC0
- EC100
- IC100
Note: Registrants can also select ‘other’ as the dose descriptor type or unit of measure. If so, the data provided is not processed for the Brief Profile.
Summary
EC50/LC50 for microorganisms provides substance information on the substance’s effect concentration or lethal concentration for 50% of the microorganisms in the test, generally displayed in milligram per litre.
EC10 / LC10 or NOEC for microorganisms provides substance information on the substance’s effect concentration/lethal concentration for 10% of the tested microorganisms or the no observed effect concentration for microorganisms. Values are generally displayed in milligram per litre.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 23 studies submitted
- 4 studies processed
- P/RResults
- EC50 (4 h) 5.8 g/L [2]
- IC50 (3 h) 1 g/L [2]
- EC100 (10 min) 39.5 g/L [2]
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | 2 | |||
Supporting study | 6 | 5 | ||
Weight of evidence | 10 | |||
Other |
Data waiving | |
---|---|
no waivers |
R Summaries
- 2 summaries submitted
- 2 summaries processed
- EC50 for microorganisms
- 5.8 g/L
Sediment toxicity
This section summarises the values related to toxicity to sediment toxicity from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. Data is generally displayed in milligrams per kilogram sediment (dry weight) or in milligram per litre.
Processable data is prioritised by the toxicity descriptor type (see list below) and subsequently further prioritised by duration (in hours, longer prioritised over shorter).
Prioritisation by dose descriptor:
- NOEC
- LOEC
- EC10
- LC10
- LD10
- EC50
- LC50
- LD50
- EC0
- LC0
- LD0
- EC100
- LC100
- LD100
- LR10
- LR50
- LR0
- LR100
Note: Registrants can also select ‘other’ as the dose descriptor type or unit of measure. If so, the data provided is not processed for the Brief Profile.
Summary
EC/LC50 for freshwater sediment provides substance information on the substance’s effect concentration or lethal concentration for 50% of the model organisms feeding off the freshwater sediment, generally displayed in milligrams per kilogram sediment (dry weight).
EC50/LC50 for marine sediment provides substance information on the substance’s effect concentration or lethal concentration for 50% of the model organisms feeding off the marine sediment, generally displayed in milligrams per kilogram sediment (dry weight).
EC10 / LC10 or NOEC for freshwater sediment provides substance information on the substance’s effect concentration/lethal concentration for 10% of the model organisms feeding off the freshwater sediment or the no observed effect concentration for of the model organisms feeding off the freshwater sediment. Values are generally displayed in milligrams per kilogram (dry weight).
EC10 / LC10 or NOEC for marine sediment provides substance information on the substance’s effect concentration/lethal concentration for 10% of the model organisms feeding off the marine sediment or the no observed effect concentration for of the model organisms feeding off the marine sediment. Values are generally displayed in milligrams per kilogram (dry weight).
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 13 studies submitted
- 0 studies processed
No automatically processable data submitted
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | ||||
Supporting study | 8 | 1 | ||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
Not feasible | |
Sci. unjustified | 1 |
Exposure cons. | 3 |
Other |
Summaries
- 3 summaries submitted
- 0 summaries processed
No automatically processable data submitted
Endocrine disrupter testing in aquatic vertebrates – in vivo
This section summarises the values related to endocrine disrupter testing in aquatic vertebrates from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. Data is generally displayed in milligrams per litre.
The availability of additional data beyond the five results displayed is indicated by (…).
Processable data is prioritised by the toxicity descriptor type (see list below) and subsequently further prioritised by duration (longer prioritised over shorter).
Prioritisation by dose descriptor:
- NOEC
- LOEC
- EC10
- LC10
- IC10
- EC50
- LC50
- IC50
- EL10
- EL50
- LL10
- LL50
- NOELR
- LOELR
Note: Registrants can also select ‘other’ as the dose descriptor type or unit of measure. If so, the data provided is not processed for the Brief Profile.
Summary
EC10 / LC10 or NOEC for freshwater fish provides substance information on the substance’s effect concentration/lethal concentration for 10% of the tested freshwater fish or the no observed effect concentration. Values are displayed in milligram per litre.
EC10 / LC10 or NOEC for marine fish provides substance information on the substance’s effect concentration/lethal concentration for 10% of the tested freshwater fish or the no observed effect concentration. Values are displayed in milligram per litre.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Data not provided by the registrant
Toxicity to terrestrial macroorganisms except arthropods
This section summarises the values related to toxicity to soil macroorganisms (except arthropods) from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. Data is generally displayed in milligrams per kilogram in the case of soil (dry/wet weight) or gram per hectare.
The availability of additional data beyond the five results displayed is indicated by (…).
Processable data is prioritised by the toxicity descriptor type (see list below) and subsequently further prioritised by duration (in hours, longer prioritised over shorter). Thirdly the display of data is prioritised by units.
Prioritisation by dose descriptor:
- NOEC
- LOEC
- EC10
- LC10
- LD10
- EC50
- LC50
- LD50
- EC0
- LC0
- LD0
- EC100
- LC100
- LD100
- LR10
- LR50
- LR0
- LR100
Prioritisation by units (dry weight):
- Mg/cm2
- g/ha
Note: Registrants can also select ‘other’ as the dose descriptor type or unit of measure. If so, the data provided is not processed for the Brief Profile.
Summary
EC/LC50 for freshwater sediment provides substance information on the substance’s effect concentration or lethal concentration for 50% of the model organisms feeding off the freshwater sediment, generally displayed in milligrams per kilogram (dry weight).
EC50/LC50 for marine sediment provides substance information on the substance’s effect concentration or lethal concentration for 50% of the model organisms feeding off the marine sediment, generally displayed in milligrams per kilogram (dry weight).
EC10 / LC10 or NOEC for freshwater sediment provides substance information on the substance’s effect concentration/lethal concentration for 10% of the model organisms feeding off the freshwater sediment or the no observed effect concentration for of the model organisms feeding off the freshwater sediment. Values are generally displayed in milligrams per kilogram (dry weight).
EC10 / LC10 or NOEC for marine sediment provides substance information on the substance’s effect concentration/lethal concentration for 10% of the model organisms feeding off the marine sediment or the no observed effect concentration for of the model organisms feeding off the marine sediment. . Values are generally displayed in measured in (nano/ micro/milli)gram per kilogram (dry weight).
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 7 studies submitted
- 0 studies processed
No automatically processable data submitted
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | ||||
Supporting study | 3 | 1 | ||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
Not feasible | |
Sci. unjustified | |
Exposure cons. | |
Other | 3 |
Summaries
- 2 summaries submitted
- 0 summaries processed
No automatically processable data submitted
Toxicity to terrestrial arthropods
This section summarises the values related to toxicity to (terrestrial) arthropods from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. Data is generally displayed in milligrams per kilogram in the case of soil (dry/wet weight), or gram per hectare. Otherwise data is displayed reported as provided by the registrant(s).
The availability of additional data beyond the five results displayed is indicated by (…).
Processable data is prioritised by the toxicity descriptor type (see list below) and subsequently further prioritised by duration (longer prioritised over shorter). Thirdly the display of data is prioritised by unit.
Prioritisation by dose descriptor:
- NOEC
- LOEC
- EC10
- LC10
- LD10
- EC50
- LC50
- LD50
- EC0
- LC0
- LD0
- EC100
- LC100
- LD100
- LR10
- LR50
- LR0
- LR100
Prioritisation by unit:
- soil dw (g/ha and mg/cm²)
- soil ww; (g/ha and mg/cm²)
- µg per animal
- mL/ha; mg/kg bw
- mg/kg diet
- ppm
- mg/kg dung dw
Note: Registrants can also select ‘other’ as the dose descriptor type or unit of measure. If so, the data provided is not processed for the Brief Profile.
Summary
Short-term EC50 or LC50 for soil dwelling arthropods provides substance information on the substance’s effect concentration or lethal concentration (short term) for 50% of the soil dwelling arthropods in the test, generally displayed in milligram per kilo soil (dry weight).
Long-term EC10 or LC10 or NOEC for soil dwelling arthropods provides substance information on the substance’s effect concentration or lethal concentration (long term) for 10% of the soil dwelling arthropods in the test, or the no observed effect concentration for soil dwelling arthropods. Values are generally displayed in milligram per kilo soil (dry weight).
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 5 studies submitted
- 0 studies processed
No automatically processable data submitted
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | ||||
Supporting study | 1 | |||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
Not feasible | |
Sci. unjustified | 1 |
Exposure cons. | |
Other | 3 |
Summaries
- 0 summaries submitted
- 0 summaries processed
No data available
Toxicity to terrestrial plants
This section summarises the values related to toxicity to (terrestrial) plants from all registered dossiers for the substance.
If more than one numerical result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method).
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. Data is generally displayed in milligrams per kilogram in the case of soil (dry/wet weight), or gram per hectare. Otherwise data is displayed reported as provided by the registrant(s).
The availability of additional data beyond the five results displayed is indicated by (…).
Processable data is prioritised by the toxicity descriptor type (see list below) and subsequently further prioritised by duration (longer prioritised over shorter). Thirdly the display of data is prioritised by units.
Prioritisation by dose descriptor:
- NOEC
- LOEC
- EC10
- LC10
- EC50
- LC50
- EC0
- EC25
- EC100
- LC0
- LC25
- LC100
- ER0
- ER10
- ER25
- ER50
- ER100
Prioritisation by units:
- soil dw (g/ha, kg/ha and lbs/acre).
- soil ww (g/ha, kg/ha and lbs/acre).
Note: Registrants can also select ‘other’ as the dose descriptor type or unit of measure. If so, the data provided is not processed for the Brief Profile.
Summary
Short-term EC50 or LC50 for terrestrial plants provides substance information on the substance’s effect concentration or lethal concentration (short term) for 50% of the terrestrial plants in the test, generally displayed in milligram per kilo soil (dry weight).
Long-term EC10 or LC10 or NOEC for terrestrial plants provides substance information on the substance’s effect concentration or lethal concentration (long term) for 10% of the terrestrial plants in the test, or the no observed effect concentration for terrestrial plants. Values are generally displayed in milligram per kilo soil (dry weight).
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 22 studies submitted
- 0 studies processed
No automatically processable data submitted
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | ||||
Supporting study | 16 | |||
Weight of evidence | 2 | |||
Other |
Data waiving | |
---|---|
Not feasible | |
Sci. unjustified | |
Exposure cons. | 1 |
Other | 3 |
R Summaries
- 3 summaries submitted
- 2 summaries processed
- Short-term EC50 / LC50
- 633 mg/kg soil dw
Toxicity to soil microorganisms
This section summarises the values related to toxicity to soil microorganisms from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. Data is generally displayed in milligrams per kilogram in the case of soil (dry/wet weight), or gram per hectare. Otherwise data is displayed reported as provided by the registrant(s).
The availability of additional data beyond the five results displayed is indicated by (…).
Processable data is prioritised by the toxicity descriptor type (see list below) and subsequently further prioritised by duration (longer prioritised over shorter). Thirdly the display of data is prioritised by units.
Prioritisation by dose descriptor:
- NOEC
- EC10
- EC25
- EC50
- EC100
- EC0
- ER0
- ER10
- ER25
- ER50
- ER100
Prioritisation by units:
- Soil dw (g/ha, kg/ha and lbs/acre).
- Soil ww (g/ha, kg/ha and lbs/acre).
Note: Registrants can also select ‘other’ as the dose descriptor type or unit of measure. If so, the data provided is not processed for the Brief Profile.
Summary
If more than one numerical result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method).
Short-term EC50 or LC50 for soil microorganisms provides substance information on the substance’s effect concentration or lethal concentration (short term) for 50% of soil microorganisms in the test, generally displayed in milligram per kilo soil (dry weight).
Long-term EC10 or LC10 or NOEC for soil microorganisms provides substance information on the substance’s effect concentration or lethal concentration (long term) for 10% of the soil microorganisms in the test, or the no observed effect concentration for soil microorganisms. Values are generally displayed in milligram per kilo soil (dry weight).
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 4 studies submitted
- 0 studies processed
No automatically processable data submitted
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | ||||
Supporting study | ||||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
Not feasible | |
Sci. unjustified | 1 |
Exposure cons. | |
Other | 3 |
Summaries
- 1 summary submitted
- 0 summaries processed
No automatically processable data submitted
Toxicity to birds
This section summarises the values related to toxicity to birds from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. Data is generally displayed in milligrams per kilogram, per bodyweight per day. Otherwise data is displayed reported as provided by the registrant(s).
The availability of additional data beyond the five results displayed is indicated by (…).
Processable data is prioritised by the toxicity descriptor type (see list below) and subsequently further prioritised by duration (longer prioritised over shorter). Thirdly the display of data is prioritised by units .
Prioritisation by dose descriptor type:
- NOEC
- LOEC
- LC50
- LD50
- LOEC
- LOEL
Prioritisation by unit:
- bw/day (mg/kg bw/day; mg/kg bw/day; mg/kg bw/day)
- mg/kg bw
- mg/kg diet
- mg/L drinking water.
Note: Registrants can also select ‘other’ as the dose descriptor type or unit of measure. If so, the data provided is not processed for the Brief Profile.
Summary
Short-term EC50 or LC50 for birds provides substance information on the substance’s effect concentration or lethal concentration (short term) for 50% of birds in the test, generally displayed in milligram per kilo food.
Long-term EC10 or LC10 or NOEC for birds provides substance information on the substance’s effect concentration or lethal concentration (long term) for 10% of the birds in the test, or the no observed effect concentration for birds. Values are generally displayed in milligram per kilo food.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 4 studies submitted
- 0 studies processed
No automatically processable data submitted
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | ||||
Supporting study | ||||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
Not feasible | |
Sci. unjustified | 1 |
Exposure cons. | 1 |
Other | 2 |
Summaries
- 2 summaries submitted
- 0 summaries processed
No automatically processable data submitted
Toxicity to mammals
This section summarises the values related to toxicity to mammals (other above-ground organisms) from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. Data is generally displayed in milligrams per kilogram in the case of soil (dry/wet weight), or gram per hectare. Otherwise data is displayed as provided by the registrant(s).
The availability of additional data beyond the five results displayed is indicated by (…).
Processable data is prioritised by the toxicity descriptor type (see list below) and subsequently further prioritised by duration (longer prioritised over shorter). Thirdly the display of data is prioritised by units.
Prioritisation by dose descriptor:
- NOEC
- EC50
- LC50
- LD50
- EC100
- LC100
- LD100
- EC0
- LC0
- LD0
- LR50
- LR0
- LR100
- ER50
- ER0
- ER100
Prioritisation by units
- Soil dw (g/ha and mg/cm²)
- Soil ww; (g/ha and mg/cm²)
- µg per animal
- mL/ha; mg/kg bw
- mg/kg diet
- ppm.
- mg/kg dung dw
Note: Registrants can also select ‘other’ as the dose descriptor type or unit of measure. If so, the data provided is not processed for the Brief Profile.
Summary
Short-term EC50 or LC50 for mammals provides substance information on the substance’s effect concentration or lethal concentration (short term) for 50% of mammals in the test, generally displayed in milligram per kilo food.
Long-term EC10 or LC10 or NOEC for mammals provides substance information on the substance’s effect concentration or lethal concentration (long term) for 10% of the mammals in the test, or the no observed effect concentration for mammals. Values are generally displayed in milligram per kilo food.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Data not provided by the registrant
Toxicological information
This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.
Derived No- or Minimal Effect Level (DN(M)EL)
This section provides information on the derived no- or minimal effect level (DN(M)EL), the level of exposure above which a human should not be exposed to a substance.
When more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.
When more than one result is available per endpoint the ‘worst case’ or most conservative of all the data values provided are displayed, applying a precautionary principal. The aim is to display the lowest values reported as causing the most adverse effects, and hence the broadest possible safety margins for the substance.
Inhalation exposure provides information on the substance’s hazard assessment conclusions regarding inhalation exposure.
Registrant can provide information on the long and acute/short term exposure for both systemic and local effects of inhalation exposure of workers and/or general population by selecting one of the following hazard assessment conclusions:
- DNEL (Derived No-Effect Level)
- DMEL (Derived Minimum Effect Level) - not included for short–term effects
- Other toxicological threshold
- High hazard (no threshold derived)
- Medium hazard (no threshold derived)
- Low hazard (no threshold derived)
- Insufficient data available (further information necessary)
- Hazard unknown (no further information necessary)
- No hazard identified
- Hazard unknown but no further hazard information necessary as no exposure expected
Prioritisation of display occurs based on the order above. If a threshold is derived, the type of hazard assessment conclusion is displayed and the registered threshold is reported in (nano/micro/milli)gram per cubic metre. If more than one DNEL/DMEL is available the most conservative (i.e. the lowest numerical data) is displayed.
Information on the most sensitive study can be provided by the registrants as:
- Acute toxicity
- Repeated dose toxicity
- Effect on fertility
- Developmental toxicity/teratogenicity
- Neurotoxicity
- Immunotoxicity
- Sensitisation (skin)
- Sensitisation (respiratory tract)
- Carcinogenicity
- Skin irritation/corrosion
- Irritation (respiratory tract)
- Genetic toxicity
Dermal exposure provides information on the substance’s hazard assessment conclusions regarding dermal exposure (for workers).
See ‘Data for workers – Inhalation exposure’, with the following additional hazard assessment conclusion in the case of short term:
- ‘No DNEL required: short term exposure controlled by conditions for long-term’ is added
The registered threshold is generally displayed in milligrams per kilogram per bodyweight per day.
Data for workers – eye exposure provides information on the substance’s hazard assessment conclusions regarding eye exposure (for workers).
Registrant can provide information on eye exposure by selecting one of the following hazard assessment conclusions:
- High hazard (no threshold derived)
- Medium hazard (no threshold derived)
- Low hazard (no threshold derived)
- Hazard unknown (no further information necessary)
- No hazard identified
- Hazard unknown but no further hazard information necessary as no exposure expected
Data for general population – eye exposure provides information on the substance’s hazard assessment conclusions regarding eye exposure (for the general population).
Registrant can provide information on eye exposure as mentioned above for ‘Data for workers – eye exposure.’
M/C Summaries
- 5 summaries submitted
- 4 summaries processed
The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.
Data for WORKERS
INHALATION Exposure | Threshold | Most sensitive study |
---|---|---|
Systemic Effects | ||
Long-term: | (DNEL) 380 mg/m³ | carcinogenicity |
Acute /short term: | No hazard identified | |
Local Effects | ||
Long-term: | No hazard identified | |
Acute /short term: | (DNEL) 1 900 mg/m³ | irritation (respiratory tract) |
DERMAL Exposure | Threshold | Most sensitive study |
Systemic Effects | ||
Long-term: | (DNEL) 343 mg/kg bw/day | repeated dose toxicity |
Acute /short term: | No hazard identified | |
Local Effects | ||
Long-term: | No hazard identified | |
Acute /short term: | No hazard identified | |
EYE Exposure | ||
Medium hazard (no threshold derived) |
Data for the GENERAL POPULATION
INHALATION Exposure | Threshold | Most sensitive study |
---|---|---|
Systemic Effects | ||
Long-term: | (DNEL) 114 mg/m³ | carcinogenicity |
Acute /short term: | No hazard identified | |
Local Effects | ||
Long-term: | No hazard identified | |
Acute /short term: | (DNEL) 950 mg/m³ | irritation (respiratory tract) |
DERMAL Exposure | Threshold | Most sensitive study |
Systemic Effects | ||
Long-term: | (DNEL) 206 mg/kg bw/day | repeated dose toxicity |
Acute /short term: | No hazard identified | |
Local Effects | ||
Long-term: | No hazard identified | |
Acute /short term: | No hazard identified | |
ORAL Exposure | Threshold | Most sensitive study |
Systemic Effects | ||
Long-term: | (DNEL) 87 mg/kg bw/day | repeated dose toxicity |
Acute /short term: | No hazard identified | |
EYE Exposure | ||
Medium hazard (no threshold derived) |
Toxicokinetics, metabolism, and distribution
This section displays the values (see below) related to toxicokinetics, metabolism, and distribution from all registered dossiers for the substance.
Study results
For this endpoint registrants do not provide study result data.
Summary
Displayed is the MOST CONSERVATIVE of the value(s) provided, ranking in the order as below.
Registrants can register their substance’s bioaccumulation properties as:
- High bioaccumulation potential
- Low bioaccumulation potential
- No bioaccumulation potential
Registrants can register their substance’s oral/dermal/inhalation absorption rate values in percentages. If multiple values are available, the most conservative value (the highest percentage) is displayed.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
Study data: basic toxicokinetics
- 56 studies submitted
- 0 studies processed
Study data not processed for brief profile
Type of Study provided
Study data: basic toxicokinetics
Studies with data | ||||
---|---|---|---|---|
Key study | 13 | |||
Supporting study | 20 | 1 | 17 | |
Weight of evidence | 1 | 4 | ||
Other |
Data waiving | |
---|---|
no waivers |
Study data: dermal absorption
- 11 studies submitted
- 0 studies processed
Study data not processed for brief profile
Study data: dermal absorption
Studies with data | ||||
---|---|---|---|---|
Key study | 6 | |||
Supporting study | 5 | |||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
no waivers |
M/C Summaries
- 3 summaries submitted
- 2 summaries processed
- Bioaccumulation potential:
- No bioaccumulation potential
- Absorption values
- Oral: 90 %
- Dermal: 21 %
- Inhalation: 75 %
Acute toxicity
This section displays the values related to acute toxicity from all registered dossiers for the substance.
Study results - oral
Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. Data is generally displayed in milligram per kilo bodyweight. The availability of additional data beyond the five results displayed is indicated by (…).
Results
Processable data for study results is prioritised by test species (see list below) and subsequently further prioritised by the dose descriptor.
Prioritization by test species:
- Rat
- Mouse
- Dog
- Cat
- Cattle
- Gerbil
- Guinea pig
- Hamster (combine hamster, Armenian; hamster, Chinese and hamster, Syrian)
- Hen
- Miniature swine
- Monkey
- Pig
- Primate
- Rabbit
- Sheep
Prioritisation by dose descriptor type:
- LD50
- LD50 cut-off
- Discriminating dose
- LD0
- LD100
- LDLo
- Approximate LD50
Note: Registrants can also select ‘other’ as the test species, dose descriptor type and/or the unit of measure. If so, the data provided is not processed for the Brief Profile.
Applicant’s summary and conclusion – Interpretation of results (oral). Registrants can choose from the following (picklist) conclusions:
- Category 1 based on GHS criteria
- Category 2 based on GHS criteria
- Category 3 based on GHS criteria
- Category 4 based on GHS criteria
- Category 5 based on GHS criteria
- Study cannot be used for classification
- GHS criteria not met
- Extremely toxic
- Very toxic
- Highly toxic
- Toxic
- Moderately toxic
- Slightly toxic
- Toxicity category I
- Toxicity category II
- Toxicity category III
- Toxicity category IV
- Toxicity category V
- Practically nontoxic
- Harmful
- Relatively harmless
- Not classified
- Other
Displayed is the MOST CONSERVATIVE of the value(s) provided, ranking in the order as above.
Note: Registrants can also select ‘other’ as the picklist conclusion. If so, the data provided is not processed for the Brief Profile.
Study results - dermal
Results
See information under ‘Study results oral’.
Applicant’s summary and conclusion – Interpretation of results (dermal). See information under ‘Applicant’s summary and conclusion – interpretation of results (oral)’.
Study results - Inhalation
Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. Data is generally displayed in milligram per kilo bodyweight. The availability of additional data beyond the five results displayed is indicated by (…).
Results
Processable data for study results is prioritised by test species (see list below) and subsequently further prioritised by the dose descriptor. Within each of these categories, data is prioritised further by duration (in hours), with longer prioritised over shorter.
Prioritization by test species:
- Rat
- Mouse
- Dog
- Cat
- Cattle
- Gerbil
- Guinea pig
- Hamster (combine hamster, Armenian; hamster, Chinese and hamster, Syrian)
- Hen
- Miniature swine
- Monkey
- Pig
- Primate
- Rabbit
- Sheep
Prioritisation by dose descriptor type:
- LC50
- LC50 cut-off
- Discriminating conc.
- LC0
- LC1
- LC100
- LCLo
Note: Registrants can also select ‘other’ as the test species, dose descriptor type and/or the unit of measure. If so, the data provided is not processed for the Brief Profile.
Applicant’s summary and conclusion – Interpretation of results (inhalation). See information under ‘Applicant’s summary and conclusion – interpretation of results (oral)’.
Study results - other routes
Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. Data is generally displayed in milligram per kilo bodyweight. The availability of additional data beyond the five results displayed is indicated by (…) icon.
Results
Processable data for study results is prioritised by test species (see list below) and subsequently further prioritised by the dose descriptor.
Prioritization by test species:
- Rat
- Mouse
- Dog
- Cat
- Cattle
- Gerbil
- Guinea pig
- Hamster (combine hamster, Armenian; hamster, Chinese and hamster, Syrian)
- Hen
- Miniature swine
- Monkey
- Pig
- Primate
- Rabbit
- Sheep
Prioritization by the dose descriptor type:
- EC50
- LC50
- LD50
- EC0
- LC0
- LD0
- EC100
- LC100
- LD100
- LCLo
- LDLo
Note: Registrants can also select ‘other’ as the test species, dose descriptor type and/or the unit of measure. If so, the data provided is not processed for the Brief Profile.
Summary
Displayed in all cases is the MOST CONSERVATIVE of the value(s) provided, ranking in the order as above, i.e. the minimum numerical value associated with the highest priority picklist item.
Oral route provides substance information on the substance’s acute toxicity via the oral route. Registrants can choose from the following picklist endpoint conclusions:
- Adverse effect observed
- No adverse effect observed
- No study available
If an adverse effect is observed, data can be provided as LD 50 or discriminating dose, displayed here in milligrams per kilogram bodyweight.
Dermal route provides substance information on the substance’s acute toxicity via the dermal route. Registrants can choose from the following picklist endpoint conclusions:
- Adverse effect observed
- No adverse effect observed
- No study available
If an adverse effect is observed, data can be provided as LD 50 or discriminating dose, displayed here in milligrams per kilogram bodyweight.
Inhalation route provides substance information on the substance’s acute toxicity via the inhalation route. Registrants can choose from the following picklist endpoint conclusions:
- Adverse effect observed
- No adverse effect observed
- No study available
If an adverse effect is observed, data can be provided as LD 50 or discriminating concentration, displayed here in milligram per cubic metre.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
oral
- 26 studies submitted
- 7 studies processed
- P/RResults
- LD50 1 187 - 15 010 mg/kg bw (rat) [6]
- LD50 7 800 - 22 500 mL/kg bw (rat) [3]
- LD50 8 300 mg/kg bw (mouse) [1]
- M/CInterpretations of results
- Not classified [6]
Type of Study provided
oral
Studies with data | ||||
---|---|---|---|---|
Key study | 3 | |||
Supporting study | 14 | 5 | ||
Weight of evidence | 3 | 1 | ||
Other |
Data waiving | |
---|---|
no waivers |
inhalation
- 16 studies submitted
- 5 studies processed
- P/RResults
- LC50 (6 h) 82.1 - 92.6 mg/L air (rat) [3]
- LC50 (4 h) 115.9 - 133.8 mg/L air (rat) [6]
- LC50 (60 min) 60 000 ppm (mouse) [2]
- M/CInterpretations of results
- Not classified [3]
inhalation
Studies with data | ||||
---|---|---|---|---|
Key study | 3 | |||
Supporting study | 6 | 5 | ||
Weight of evidence | 2 | |||
Other |
Data waiving | |
---|---|
no waivers |
dermal
- 6 studies submitted
- 0 studies processed
No automatically processable data submitted
dermal
Studies with data | ||||
---|---|---|---|---|
Key study | ||||
Supporting study | 2 | |||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
Not feasible | |
Sci. unjustified | 2 |
Exposure cons. | |
Other | 2 |
other routes
- 6 studies submitted
- 0 studies processed
No automatically processable data submitted
other routes
Studies with data | ||||
---|---|---|---|---|
Key study | ||||
Supporting study | 6 | |||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
no waivers |
M/C Summaries
- 4 summaries submitted
- 1 summary processed
- Oral route:
- No adverse effect observed LD50 8 300 mg/kg bw
Irritation / corrosion
This section displays the values related to irritation and corrosion from all registered dossiers for the substance.
Study results
For this endpoint registrants do not provide study results that are processable for the Brief Profile.
Summary
Displayed in all cases is the MOST CONSERVATIVE of the value(s) provided, ranking in the order as below.
Skin irritation/corrosion provides substance information on the substance’s irritation/corrosion effect on the skin. Registrants can choose from the following picklist endpoint conclusions/effect levels:
Endpoint conclusion – picklist
- Adverse effect observed (irritating)
- Adverse effect observed (corrosive)
- No adverse effect observed (not irritating)
- No study available
Eye irritation provides substance information on the substance’s irritation effect on the eye. Registrants can choose from the following picklist endpoint conclusions/effect levels:
- Adverse effect observed (irreversible damage)
- Adverse effect observed (irritating)
- No adverse effect observed (not irritating)
- No study available
Respiratory irritation provides substance information on the substance’s irritation effect on the respiratory system. Registrants can choose from the following picklist endpoint conclusions/effect levels:
- <
- Adverse effect observed (irritating)
- No adverse effect observed (not irritating)
- No study available
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
Study data: skin
- 24 studies submitted
- 0 studies processed
Study data not processed for brief profile
Type of Study provided
Study data: skin
Studies with data | ||||
---|---|---|---|---|
Key study | 2 | 1 | ||
Supporting study | 20 | |||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
Not feasible | |
Sci. unjustified | 1 |
Exposure cons. | |
Other |
Study data: eye
- 17 studies submitted
- 0 studies processed
Study data not processed for brief profile
Study data: eye
Studies with data | ||||
---|---|---|---|---|
Key study | 3 | 1 | ||
Supporting study | 11 | |||
Weight of evidence | 1 | |||
Other |
Data waiving | |
---|---|
Not feasible | |
Sci. unjustified | 1 |
Exposure cons. | |
Other |
M/C Summaries
- 4 summaries submitted
- 3 summaries processed
- Skin
- No adverse effect observed (not irritating)
- Eye
- Adverse effect observed (irritating)
Sensitisation
This section displays the values related to sensitisation from all registered dossiers for the substance.
Study results
For this endpoint registrants do not provide study results that are processable for the Brief Profile.
Summary
Displayed in all cases is the MOST CONSERVATIVE of the value(s) provided, ranking in the order as below.
Skin sensitisation provides substance information on the substance’s sensitisation effect on the skin. Registrants can choose from the following picklist endpoint conclusions:
- Adverse effect observed
- No adverse effect observed (not irritating)
- No study available
Respiratory sensitisation provides substance information on the substance’s sensitisation effect on the respiratory system. Registrants can choose the same picklist endpoint conclusions as mentioned under ‘Skin sensitisation’.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
Study data: skin
- 7 studies submitted
- 0 studies processed
Study data not processed for brief profile
Type of Study provided
Study data: skin
Studies with data | ||||
---|---|---|---|---|
Key study | 1 | |||
Supporting study | ||||
Weight of evidence | 4 | |||
Other |
Data waiving | |
---|---|
Not feasible | |
Sci. unjustified | 2 |
Exposure cons. | |
Other |
Study data: respiratory
- 3 studies submitted
- 0 studies processed
Study data not processed for brief profile
Study data: respiratory
Studies with data | ||||
---|---|---|---|---|
Key study | ||||
Supporting study | 3 | |||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
no waivers |
M/C Summaries
- 4 summaries submitted
- 2 summaries processed
- Skin sensitisation
- No adverse effect observed (not sensitising)
- Respiratory sensitisation
- No adverse effect observed (not sensitising)
Repeated dose toxicity
This section displays the values related to repeated dose toxicity from all registered dossiers for the substance.
Study results oral
Processable data for study results is prioritised by dose descriptor type (see list below) and subsequently further prioritised by the test species. Thirdly the display of data is prioritised by units.
Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. Data is generally displayed in milligrams per kilogram bodyweight per day.
The availability of additional data beyond the five results displayed is indicated by (…).
Prioritization by dose descriptor type:
- NOAEL
- LOAEL
- NOEL
- LOEL
- BMD05
- BMDL05
- BMDL10
- BMC05
- BMCL05
- BMCL10
- no NOAEL identified
Note: Registrants can also select ‘BMD’, ‘BMC’, ‘dose level’ and ‘conc. level’ as the dose descriptor. If so, the data provided is not processed for the Brief Profile.
Prioritisation by test species:
- Rat
- Mouse
- Dog
- Cat
- Cattle
- Gerbil
- Guinea pig
- Hamster (combine hamster, Armenian; hamster, Chinese and hamster, Syrian)
- Hen
- Miniature swine
- Monkey
- Pig
- Primate
- Rabbit
- Sheep
Prioritisation by units:
- mg/kg bw/day (nominal/actual dose received)
- mg/kg diet
- mg/L drinking water
- mg/kg bw (total dose)
- ppm
Note: Registrants can also select ‘other’ as the test species, dose descriptor type and/or the unit of measure. If so, the data provided is not processed for the Brief Profile.
Study results inhalation
Processable data for study results is prioritised by dose descriptor type (see list below) and subsequently further prioritised by the test species. Thirdly the display of data is prioritised by units.
Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. Data is generally displayed in milligram per litre air.
The availability of additional data beyond the five results displayed is indicated by (…).
Prioritization by dose descriptor type:
- NOAEL
- LOAEL
- NOEL
- LOEL
- NOAEC
- NOEC
- LOAEC
- LOEC
- BMD05
- BMDL05
- BMDL10
- BMC05
- BMCL05
- BMCL10
- no NOAEL identified
- no NOAEC identified
Note: Registrants can also select ‘BMD’, ‘BMC’, ‘dose level’ and ‘conc. level’ as the dose descriptor. If so, the data provided is not processed for the Brief Profile.
Prioritization by test species:
- See ‘Study results oral: Prioritization by test species’
Prioritisation by unit:
- mg/L air (combining mg/L air, mg/L air (nominal), mg/L air (analytical), mg/m³ air, mg/m³ air (nominal), mg/m³ air (analytical))
- ppm (combine ppm, ppm (nominal), ppm (analytical), mg/kg bw/day (actual dose received)
Note: Registrants can also select ‘other’ as the test species, dose descriptor type and/or the unit of measure. If so, the data provided is not processed for the Brief Profile.
Study results dermal
See ‘Study results Oral’, except:
Prioritisation by unit:
- mg/kg bw/day (combining mg/kg bw/day (nominal), mg/kg bw/day (actual dose received) and mg/kg bw/day)
- mg/kg bw (total dose)
- mg/cm² per day (combining mg/cm² per day, mg/cm² per day (nominal), mg/cm² per day (analytical))
Note: Registrants can also select ‘other’ as the test species, dose descriptor type and/or the unit of measure. If so, the data provided is not processed for the Brief Profile.
Summary oral – systemic effects
Processable data for the summary is prioritised by test species (see list below) and subsequently further prioritised by the dose descriptor. Displayed is the most conservative of the prioritised value(s). If more than one result with the same value, data is further prioritised by test type and endpoint conclusion.
Data is generally displayed in milligrams per kilogram bodyweight per day.
Prioritization by test species:
- Rat
- Mouse
- Dog
- Cat
- Cattle
- Gerbil
- Guinea pig
- Hamster (combine hamster, Armenian; hamster, Chinese and hamster, Syrian)
- Hen
- Miniature swine
- Monkey
- Pig
- Primate
- Rabbit
- Sheep
Prioritisation by descriptor type:
- NOAEL
- LOAEL
- T25
- BMDL05
- BMD05
- BMDL10
Prioritisation by test type:
- Chronic
- Subchronic
- Subacute
Prioritisation by endpoint conclusion:
- Adverse effect observed
- No adverse effect observed
- No study available / no study available (further information necessary)
Summary dermal - systemic effects
See ‘Summary oral systemic effects’
Summary dermal - local effects
See ‘Summary oral systemic effects’, except:
Unit of measure: mg/cm2
Summary inhalation - systemic effects
See ‘Summary oral Route’, except:
Unit of measure: mg/m3
Prioritisation by dose descriptor type:
- NOAEC
- LOAEC
- BMCL05
- BMC05
- BMCL10
- T25
Summary inhalation - local effects
‘See Summary inhalation systemic effects’
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
Study data: oral
- 22 studies submitted
- 2 studies processed
- P/RResults
- NOAEL (rat): 1 730 mg/kg bw/day [1]
- NOAEL (mouse): 9 700 mg/kg bw/day [1]
- NOAEL (mouse): 9 400 mg/kg bw (total dose) [1]
- LOAEL (rat): 3 200 mg/kg bw/day [1]
Type of Study provided
Study data: oral
Studies with data | ||||
---|---|---|---|---|
Key study | 2 | |||
Supporting study | 18 | 1 | ||
Weight of evidence | 1 | |||
Other |
Data waiving | |
---|---|
no waivers |
Study data: inhalation
- 24 studies submitted
- 4 studies processed
- P/RResults
- NOAEC (rat): 6.66 mg/L air [1]
- NOAEC (mouse): 1.3 mg/L air [1]
- NOAEC (monkey): 13 mg/m³ air [1]
- NOEC (rat): 130 mg/m³ air [1]
- NOEC (mouse): 130 mg/m³ air [1]
Study data: inhalation
Studies with data | ||||
---|---|---|---|---|
Key study | ||||
Supporting study | 11 | 7 | ||
Weight of evidence | 4 | |||
Other |
Data waiving | |
---|---|
Not feasible | |
Sci. unjustified | 2 |
Exposure cons. | |
Other |
Study data: dermal
- 3 studies submitted
- 0 studies processed
No automatically processable data submitted
Study data: dermal
Studies with data | ||||
---|---|---|---|---|
Key study | ||||
Supporting study | ||||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
Not feasible | |
Sci. unjustified | 1 |
Exposure cons. | |
Other | 2 |
M/C Summaries
- 4 summaries submitted
- 1 summary processed
- Oral route - systemic effects:
- No adverse effect observed NOAEL 9 400 mg/kg bw/day (subchronic, mouse)
Genetic toxicity
This section displays the values related to genetic toxicity from all registered dossiers for the substance.
Study results
For this endpoint registrants do not provide study results that are processable for the Brief Profile.
Summary
Processable data for study results is prioritised by endpoint conclusion: the most conservative value is displayed.
Prioritisation by endpoint conclusion:
- Adverse effect observed
- No adverse effect observed
- No study available / no study available (further information necessary)
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
Study data: in vitro
- 59 studies submitted
- 0 studies processed
Study data not processed for brief profile
Type of Study provided
Study data: in vitro
Studies with data | ||||
---|---|---|---|---|
Key study | 6 | 3 | ||
Supporting study | 36 | 6 | ||
Weight of evidence | 6 | |||
Other | 2 |
Data waiving | |
---|---|
no waivers |
Study data: in vivo
- 42 studies submitted
- 0 studies processed
Study data not processed for brief profile
Study data: in vivo
Studies with data | ||||
---|---|---|---|---|
Key study | 2 | |||
Supporting study | 31 | 1 | ||
Weight of evidence | 5 | |||
Other | 3 |
Data waiving | |
---|---|
no waivers |
Summaries
- 3 summaries submitted
- 0 summaries processed
No automatically processable data submitted
Carcinogenicity
This section displays the values related to carcinogenicity from all registered dossiers for the substance.
Study results
Study results are not processed for carcinogenicity in the context of Brief Profiles due to the use of complex field(s) to report the information, which cannot be easily summarised by an automatic algorithm.
Summary oral route
Processable data for summary is prioritised by test species (see list below) and subsequently further prioritised by the dose descriptor. Displayed is the most conservative of the prioritised value(s). If there is more than one result with the same value, data is further prioritised by test type and endpoint conclusion.
Data is generally displayed in milligrams per kilogram bodyweight per day.
Prioritization by test species:
- Rat
- Mouse
- Dog
- Cat
- Cattle
- Gerbil
- Guinea pig
- Hamster (combine hamster, Armenian; hamster, Chinese and hamster, Syrian)
- Hen
- Miniature swine
- Monkey
- Pig
- Primate
- Rabbit
- Sheep
Note: Registrants can also select ‘other’ as the test species. If so, the data provided is not processed for the Brief Profile.
Prioritisation by descriptor type:
- NOAEL
- LOAEL
- T25
- BMDL05
- BMD05
- BMDL10
Prioritisation by test type:
- Chronic
- Subchronic
- Subacute
Prioritisation by endpoint conclusion:
- Adverse effect observed
- No adverse effect observed
- No study available / no study available (further information necessary)
Summary dermal route
See ‘Summary oral Route’
Summary inhalation route
See ‘Summary oral Route’, except:
Measurement units: mg/m3
Prioritisation by dose descriptor type:
- NOAEC
- LOAEC
- BMCL05
- BMC05
- BMCL10
- T25
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 27 studies submitted
- 0 studies processed
Study data not processed for brief profile
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | 2 | |||
Supporting study | 5 | 1 | ||
Weight of evidence | ||||
Other | 19 |
Data waiving | |
---|---|
no waivers |
Summaries
- 2 summaries submitted
- 0 summaries processed
No automatically processable data submitted
Toxicity to reproduction
This section displays the values related to reproductive toxicity from all registered dossiers for the substance.
Study results
Study results are not processed for carcinogenicity in the context of Brief Profiles due to the use of complex field(s) to report the information, which cannot be easily summarised by an automatic algorithm.
Summary effect on fertility oral route
Processable data for study results is prioritised by test species (see list below) and subsequently further prioritised by the dose descriptor. Displayed is the most conservative of the prioritised value(s). If there is more than one result with the same value, data is further prioritised by test type and endpoint conclusion.
Data is generally displayed in milligrams per kilogram bodyweight per day.
Prioritization by test species:
- Rat
- Mouse
- Dog
- Cat
- Cattle
- Gerbil
- Guinea pig
- Hamster (combine hamster, Armenian; hamster, Chinese and hamster, Syrian)
- Hen
- Miniature swine
- Monkey
- Pig
- Primate
- Rabbit
- Sheep
Note: Registrants can also select ‘other’ as the test species. If so, the data provided is not processed for the Brief Profile.
Prioritisation by descriptor type:
- NOAEL
- LOAEL
- T25
- BMDL05
- BMD05
- BMDL10
Prioritisation by test type:
- Chronic
- Subchronic
- Subacute
Prioritisation by endpoint conclusion:
- Adverse effect observed
- No adverse effect observed
- No study available / no study available (further information necessary)
Summary effect on fertility dermal route
See ‘Summary effect on fertility oral route’
Summary effect on fertility inhalation route
See ‘Summary effect on fertility oral route’, except:
Dose descriptor prioritization:
- NOAEC
- LOAEC
- BMCL01
- BMC05
- BMCL10
Measurement units: mg/m3
Summary developmental toxicity oral route
See ‘Summary effect on fertility oral route’
Summary developmental toxicity dermal route
See ‘Summary effect on fertility oral route’
Summary developmental toxicity inhalation route
See ‘Summary effect on fertility oral route’, except:
Dose descriptor prioritization:
- NOAEC
- LOAEC
- BMCL01
- BMC05
- BMCL10
Measurement units: mg/m3
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
Study data: reproduction
- 44 studies submitted
- 0 studies processed
Study data not processed for brief profile
Type of Study provided
Study data: reproduction
Studies with data | ||||
---|---|---|---|---|
Key study | 3 | |||
Supporting study | 38 | 1 | ||
Weight of evidence | 2 | |||
Other |
Data waiving | |
---|---|
no waivers |
Study data: developmental
- 88 studies submitted
- 0 studies processed
Study data not processed for brief profile
Study data: developmental
Studies with data | ||||
---|---|---|---|---|
Key study | 6 | |||
Supporting study | 67 | 10 | ||
Weight of evidence | 4 | |||
Other | 1 |
Data waiving | |
---|---|
no waivers |
Study data: other studies
- 3 studies submitted
- 0 studies processed
Study data not processed for brief profile
Study data: other studies
Studies with data | ||||
---|---|---|---|---|
Key study | ||||
Supporting study | 2 | |||
Weight of evidence | ||||
Other | 1 |
Data waiving | |
---|---|
no waivers |
M/C Summaries
- 3 summaries submitted
- 1 summary processed
- Effect on fertility
- Oral route:
- No adverse effect observed NOAEL 20 700 mg/kg bw/day (subchronic, mouse)
- Effect on developmental toxicity
- Inhalation route:
- No adverse effect observed NOAEC 30 400 mg/m³ (subchronic, rat)
Neurotoxicity
This section displays the values related to neurotoxicity from all registered dossiers for the substance.
Study results
For this endpoint registrants do not provide study results that are processable for the Brief Profile.
Summary oral route
Processable data for study results is prioritised by test species (see list below) and subsequently further prioritised by the dose descriptor. Displayed is the most conservative of the prioritised value(s). If there is more than one result with the same value, data is further prioritised by test type and endpoint conclusion.
Data is generally displayed in milligrams per kilogram bodyweight per day.
Prioritization by test species:
- Rat
- Mouse
- Dog
- Cat
- Cattle
- Gerbil
- Guinea pig
- Hamster (combine hamster, Armenian; hamster, Chinese and hamster, Syrian)
- Hen
- Miniature swine
- Monkey
- Pig
- Primate
- Rabbit
- Sheep
Prioritisation by descriptor type:
- NOAEL
- LOAEL
- T25
- BMDL05
- BMD05
- BMDL10
Prioritisation by test type:
- Chronic
- Subchronic
- Subacute
Prioritisation by endpoint conclusion:
- Adverse effect observed
- No adverse effect observed
- No study available / no study available (further information necessary)
Summary dermal route
See ‘Summary oral route’
Summary inhalation route
See ‘Summary oral route’, except:
Dose descriptor prioritization:
- NOAEC
- LOAEC
- BMCL01
- BMC05
- BMCL10
Measurement units: mg/m3
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 23 studies submitted
- 0 studies processed
Study data not processed for brief profile
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | ||||
Supporting study | 23 | |||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
no waivers |
M/C Summaries
- 2 summaries submitted
- 1 summary processed
- Inhalation route:
- Adverse effect observed NOAEC 19 000 mg/m³ (subchronic, rat)
Immunotoxicity
This section displays the values related to immunotoxicity from all registered dossiers for the substance.
Study results
For this endpoint registrants do not provide study results that are processable for the Brief Profile.
Summary oral route
Processable data for study results is prioritised by test species (see list below) and subsequently further prioritised by the dose descriptor. Displayed is the most conservative of the prioritised value(s). If there is more than one result with the same value, data is further prioritised by test type and endpoint conclusion.
Data generally displayed in milligrams per kilogram bodyweight per day.
Prioritization by test species:
- Rat
- Mouse
- Dog
- Cat
- Cattle
- Gerbil
- Guinea pig
- Hamster (combine hamster, Armenian; hamster, Chinese and hamster, Syrian)
- Hen
- Miniature swine
- Monkey
- Pig
- Primate
- Rabbit
- Sheep
Prioritisation by descriptor type:
- NOAEL
- LOAEL
- T25
- BMDL05
- BMD05
- BMDL10
Prioritisation by test type:
- Chronic
- Subchronic
- Subacute
Prioritisation by endpoint conclusion:
- Adverse effect observed
- No adverse effect observed
- No study available / no study available (further information necessary)
Note: Registrants can also select ‘other’ as the test species, dose descriptor type and/or the unit of measure. If so, the data provided is not processed for the Brief Profile.
Summary dermal route
See ‘Summary oral route’
Summary inhalation route
See ‘Summary oral route’, except:
Dose descriptor prioritization:
- NOAEC
- LOAEC
- BMCL01
- BMC05
- BMCL10
Measurement units: mg/m3
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 3 studies submitted
- 0 studies processed
Study data not processed for brief profile
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | ||||
Supporting study | 3 | |||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
no waivers |
M/C Summaries
- 1 summary submitted
- 1 summary processed
- Inhalation route:
- No adverse effect observed NOAEC 40 000 mg/m³ (subchronic, rat)
Endocrine disrupter mammalian screening - in vivo
This section displays the values related to endocrine disrupter mammalian screening from all registered dossiers for the substance.
Study results
If more than one value is available, results are displayed as concatenated distinct values, ordered by most to least commonly provided, with the % of provided values appended. The % is based on count of values provided.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Data not provided by the registrant
- Physical and chemical properties
- Appearance/physical state / colour
- Melting/freezing point
- Boiling point
- Density
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising
- Oxidation reduction potential
- pH
- Dissociation constant
- Viscosity
- Environmental fate and pathways
- Phototransformation in air
- Hydrolysis
- Phototransformation in water
- Phototransformation in soil
- Biodegradation in water - screening tests
- Biodegradation in water & sediment - simulation tests
- Biodegradation in soil
- Bioaccumulation: aquatic / sediment
- Bioaccumulation: terrestrial
- Adsorption/desorption
- Henrys law constant (H)
- Distribution modelling
- Ecotoxicological information
- Predicted No-Effect Concentration (PNEC)
- Short–term toxicity to fish
- Long–term toxicity to fish
- Short–term toxicity to aquatic invertebrates
- Long–term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Sediment toxicity
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to terrestrial macroorganisms except arthropods
- Toxicity to terrestrial arthropods
- Toxicity to terrestrial plants
- Toxicity to soil microorganisms
- Toxicity to birds
- Toxicity to mammals
- Toxicological information
- Derived No- or Minimal Effect Level (DN(M)EL)
- Toxicokinetics, metabolism, and distribution
- Acute toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Neurotoxicity
- Immunotoxicity
- Endocrine disrupter mammalian screening - in vivo
The brief profile is based on non-confidential data contained in ECHA’s databases at the time of generation. Please be aware that as additional data is submitted to ECHA, the brief profile will also be updated to reflect the new situation. All data remain the property of its respective owners.
Note that the brief profile is an automatically generated summary and that not all available data may be displayed. The content is subject to change without prior notice. The information has not been reviewed or verified by ECHA or any other authority. The Agency thus cannot guarantee the correctness of the information displayed. The identification of applicable legislative frameworks is done automatically and without manual verification. Therefore this does not constitute official and legally binding information. To confirm if a substance is covered by a specific legislative framework the official publication should be consulted.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner. The Agency does not take any responsibility whatsoever for any copyright or other infringements that may be caused by using the information. This brief profile is covered by the ECHA Legal Notice.
Helpful information
Lorem ipsum dolor sit amet, consectetur adipiscing elit. Praesent et nulla orci. Aliquam nec erat semper, suscipit libero et, bibendum mauris. Nam ante ipsum, suscipit non sapien nec, congue consequat ante. Vivamus mauris lorem, fringilla at diam a, laoreet consequat eros. Nulla pulvinar vitae nunc vitae sagittis. Proin faucibus mollis lectus ut fermentum. Duis pulvinar non magna ac viverra. Fusce eget lorem sed purus tempus blandit. Vestibulum tincidunt ultricies libero quis mollis. Suspendisse porttitor leo quis purus porttitor posuere sit amet sit amet nunc. Sed elementum odio augue, eget iaculis lorem faucibus vel.
Lorem ipsum dolor sit amet, consectetur adipiscing elit. Praesent et nulla orci. Aliquam nec erat semper, suscipit libero et, bibendum mauris. Nam ante ipsum, suscipit non sapien nec, congue consequat ante. Vivamus mauris lorem, fringilla at diam a, laoreet consequat eros. Nulla pulvinar vitae nunc vitae sagittis. Proin faucibus mollis lectus ut fermentum. Duis pulvinar non magna ac viverra. Fusce eget lorem sed purus tempus blandit. Vestibulum tincidunt ultricies libero quis mollis. Suspendisse porttitor leo quis purus porttitor posuere sit amet sit amet nunc. Sed elementum odio augue, eget iaculis lorem faucibus vel.