Registration Dossier
Registration Dossier
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EC number: 232-019-7 | CAS number: 7783-66-6
Endpoint summary
Administrative data
Description of key information
The substance is corrosive to skin and eyes.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (corrosive)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Respiratory irritation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
Iodine pentafluoride is a highly reactive substance which immediately decomposes in contact with water or moisture to produce hydrofluoric acid and iodic acid.Both acids are corrosive to skin and eyes. From this it follows that iodine pentafluoride is also corrosive to the skin and eyes.The skin corrosive properties of iodine pentafluoride were confirmed in an in vivo study predating OECD and GLP guidelines (Hanzlik, 1919). In this study iodine pentafluoride was found to be a severe irritant as indicated by hyperemia, swelling and edema, ulceration, necrosis, etc., on dog's skin and similar changes together with vesication on human skin.
Effects on skin irritation/corrosion: corrosive
Effects on eye irritation: corrosive
Justification for classification or non-classification
Due to the fact that the substance reacts violently with moisture always present in the skin, and produces hydrofluoric and iodic acids, both corrosive to skin and eyes, the substance should be classified as Corrosive Cat. 1A, H314 (Causes severe skin burns and eye damage) according to the EU Classification, Labeling and Packaging of Substances and Mixtures (CLP) Regulation (EC) No. 1272/2008. According to EU Directive 67/548/EEC the substance should be classified as C, R35 (Causes severe burns).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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