Iodine pentafluoride

Endpoint summary

Additional information

No aquatic toxicity studies with iodine pentafluoride are available or can be performed as in contact with water iodine pentafluoride reacts instantly and violently under formation of hydrogen fluoride and iodate. Hydrogen fluoride will further react to fluoride, iodate in water forms an equilibrium with iodide. Therefore available data from studies with fluoride, iodate and iodide are given as indication of the aquatic toxicity of iodine pentafluoride. If no data on iodate and iodide is available, read across is made to the aquatic toxicity data of iodine.

Short-term toxicity studies in fish are available for all three IF5 decomposition products. For fluoride several studies performed with sodium fluoride in different fish species are available. From these studies, the lowest effect value is a 96 -h LC50 of 51 mg fluoride/L in rainbow trout. For sodium -iodate and -iodide a single study is available also in rainbow trout. The 96 -h LC50 values for iodate and iodide in this study are 220 and 860 mg/L, respectively.

Short-term toxicity studies in aquatic invertebrates are available for all three IF5 decomposition products. For fluoride several studies performed with sodium fluoride in different aquatic invertebrates are available. From these studies, the lowest effect value is a 96 -h EC50 of 26 mg fluoride/L in benthic macroinvertebrates. For sodium -iodate and -iodide a single study with Daphnia magna is available. The 48 -h LC50 values for iodate and iodide in this study are 10.3 and 0.17 mg/L, respectively.

Toxicity studies in algae are available for fluoride and iodine. For fluoride several studies performed with sodium fluoride in different algae species are available. From these studies, the lowest effect value is a 96 -h EC50 for biomass of 43 mg fluoride/L in Scenedesmus sp.. For iodine a single study with desmodesmus subspicatus is available. The 72 -h EC50 for growth rate is 0.13 mg/L. The corresponding NOEC was 0.025 mg/L. Correction of these effect values for the molecular weights of iodate and iodide gives EC50 values of 0.18 and 0.13 mg/L, respectively, and NOEC values of 0.035 mg/L and 0.025 mg/L, respectively.

Long-term ecotoxicological information is available only for fluoride.

For fish, a long-term NOEC is available for fluoride from a 21 -day study with Oncorhynchus mykiss. In this study a LC5 value of 4 mg fluoride/L was reported which is considered equivalent to the NOEC for mortality. This test was carried out in very soft water (12 mg CaCO3/L).

For aquatic invertebrates, two 21 -day studies with fluoride are reported which provide NOEC values based on reproduction. The arithmetic mean of both studies gives a NOEC value of 8.9 mg fluoride/L.

Toxicity studies with microorganisms are available for fluoride and iodine. For fluoride several studies performed with sodium fluoride in different microorganisms are available. From these studies, only two can theoretically be used for deriving a PNEC for fluoride. The critical effect value is a 3 -h EC10 value of 510 mg/ fluoride/L in activated sludge. For iodine a single respiration inhibition test with activated sludge is available. The 3 -h EC50 is 280 mg/L and the 3 -h EC10 is 110 mg/L for iodine. Correction of these effect values for the molecular weights of iodate and iodide gives EC50 values of 388 and 280 mg/L, respectively, and EC10 values of 152 mg/L and 110 mg/L, respectively.