Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 234-634-6 | CAS number: 12018-10-9
Carcinogenicity
Administrative data
Description of key information
Key value for chemical safety assessment
Justification for classification or non-classification
Refer to the corresponding section of the CuO and Cr2O3 CSRs.
Copper dichromium tetraoxide is highly insoluble and is not classified following exposure by the oral, dermal or inhalation routes. For risk assessment purposes, it is assumed to have a similar toxicity profile to copper oxide and chromium (III) oxide, two relatively insoluble copper and chromium (III) substances.
Although the available animal and human data on the carcinogenicity of copper and its compounds are deficient in several respects, it was concluded that the findings do not raise concerns with respect to carcinogenic activity. Consequently, further tests investigating this end-point were not recommended.
In the case of chromium (III) oxide, there are no studies in animals showing clear evidence of Cr (III) carcinogenicity. Studies of workers in tanneries reported no association between exposure to chromium (III) and excess risk of cancer. The results of the available studies do not trigger classification according to CLP/GHS criteria.
In view of the above it is concluded that copper dichromium tetraoxide does not have carcinogenic potential.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
