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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
comparable to guideline study with acceptable restrictions

Data source

Reference
Reference Type:
secondary source
Title:
EHC 216
Year:
2000
Bibliographic source:
http://www.safe.nite.go.jp/english/ghs/11-mhlw-0074e.html

Materials and methods

GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Chloroacetonitrile
EC Number:
203-467-0
EC Name:
Chloroacetonitrile
Cas Number:
107-14-2
Molecular formula:
C2H2ClN
IUPAC Name:
2-chloroacetonitrile
Test material form:
liquid

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
oral: unspecified
Control animals:
not specified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
152.8 mg/kg bw
Based on:
test mat.
Mortality:
Not specified
Clinical signs:
other: Not specified
Gross pathology:
Not specified

Applicant's summary and conclusion

Interpretation of results:
Category 3 based on GHS criteria