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EC number: 274-572-7
CAS number: 70331-94-1
In Vitro Assay of Uniroyal Compound
TVIC-B-5909 Using Salmonella typhimurium (Averages)
μg of Compound Added per Plate
Histidine-Positive Revertants per Plate
The purpose of the study is to determine whether the compound (TVIC)
elicited a mutagenic response in microorganism. An Aroclor
1254-stimulated, rat-liver-homogenate metabolic activation system was
included in the assay procedure to provide metabolic steps that the
bacteria are either incapable of conducting or that they do not carry
our under the assay conditions.
The test method conformed to the procedure published by Ames et al. Mut
Res 31:347-364, 1975.
Compound TVIC was examined for mutagenic activity with Salmonella
typhimurium strains TA 98, TA 100, TA 1535, TA 1537, TA 1538. Each assay
was performed in the presence and in the absence of a metabolic
activation system. The compound assayed was found to be non-mutagenic.
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