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EC number: 274-572-7
CAS number: 70331-94-1
Primary irritation scores in New Zealand
White rabbits following a 24-hour patch application of TVCI B-5909
Score for Rabbit Number
Erythema and Eschar Formation
Primary Irritation Index 0
Site Key – Dorsal View of Rabbit
The purpose of this study was to evaluate the acute dermal irritation
potential of the test material in accordance with Section 162.81 of the
Regulations for the Enforcement of the Federal Insecticide, Fungicide,
and Rodenticide Act, (Federal Register, Wednesday, June 25, 1975).
0.5g of the undiluted test material was moistened with and applied to
two intact skin areas and two abraded skin areas on each of six New
Zealand White rabbits.
At the end of the 24-hour exposure period, the patches were removed and
any residual sample was gently wiped from the skin with a soft dry towel.
The reactions were scored immediately after removal of the patches
24-hour reading, and again two days later 72-hour reading.
TVCI B-5909 produced no irritating effects following application to the
intact and abraded skin of New Zealand White rabbits.
The primary irritation index was found to be 0.
Based on these results TVCI B-5909 is classified in Toxicity IV for skin
effects as these categories are described in Section 162.10 of the
above-ci ted Regulations (Federal Register, Thursday, July 3, 1975).
This corresponds to "not irritating" under The CLP Regulation. European
Regulation (EC) No 1272/2008.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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