Registration Dossier
Registration Dossier
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EC number: 410-510-9 | CAS number: 86753-82-4
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- other: Body responsible for the test
- Title:
- Unnamed
- Year:
- 1 991
- Report date:
- 1991
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: Annex V - method B.1
- GLP compliance:
- yes
- Test type:
- standard acute method
- Limit test:
- yes
Test material
Constituent 1
Test animals
- Species:
- other: Rat (Wistar-derived)
Administration / exposure
- Vehicle:
- corn oil
Results and discussion
Effect levels
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- > 2 000 mg/kg bw
- Mortality:
- Male: > 2000 mg/kg bw; Number of animals: 5; Number of deaths: 0Female: > 2000 mg/kg bw; Number of animals: 5; Number of deaths: 0
- Clinical signs:
- other: Signs of toxicity related to dose levels:No significant signs of toxicity were observed
- Gross pathology:
- Effects on organs:No macroscopic abnormalities were detected at post mortem
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated informationCriteria used for interpretation of results: EU
- Conclusions:
- The acute oral median lethal dose of the substance was greater than 2000 mg/kg to both male and female rats.
- Executive summary:
A group of 5 male and 5 female rats each received a single oral dose of 2000 mg/kg of the substance. The animals were assessed daily for any signs of systemic toxicity and their bodyweights were recorded at intervals.
No significant signs of toxicity were observed and none of the animals died. the test sample stained yellow the tail, coat and faeces of some of the animals.
The acute oral median lethal dose of the substance was greater than 2000 mg/kg to both male and female rats.
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