Registration Dossier
Registration Dossier
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EC number: 215-684-8 | CAS number: 1344-00-9
Endpoint summary
Administrative data
Description of key information
Bioaccumulation can be regarded as not applicable as the substance shows a log Pow <3.
Additional information
Bioaccumulation is not applicable because silicon dioxide/silicate, including the synthetic amorphous Silicic acid, aluminum sodium salt (CAS 1344-00-9, NAS), represents a class of inorganic compounds with a log Pow <3. Furthermore, due to its inherent chemico-physical properties, such as the absence of lipophilicity as well as the capability of the organism to excrete absorbed silicates, bioaccumulation can be disregarded. However, silica/silicate can be actively accumulated by terrestrial plants (e.g. grass) and some marine organisms (e.g. diatoms, radiolarians, and sponges), which represents a normal natural process. Silicon is the second most abundant element in the Earth’s crust mass (approx. 28 %) after oxygen. It appears as complex silicate minerals in soils and sediments, as the oxide (silica, SiO2) in crystalline form in rocks, soils and sand, and as biogenic silica in organisms such as diatoms, radiolarians, or silicoflagellates and in plants such as grass, rushes, rice or sugar cane. Thus, organisms are already adapted to silicate, and exposure to synthetic amorphous Silicic acid, aluminum sodium salt (CAS 1344-00-9, NAS) is not expected to lead to adverse effects. The same applies to aluminum which is the third most abundant element (approx. 8%) in the Earth's crust.
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