reaction mass of isomers of: C7-9-alkyl 3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionate

Endpoint summary

Additional information

Assessment of the parent compound Benzenepropanoic acid, 3,5-bis(1,1-dimethylethyl)-4-hydroxy-,C7-9-branched alkyl esters (CAS: 125643 -61 -0)

The terrestrial toxicity of Benzenepropanoic acid, 3,5-bis(1,1-dimethylethyl)-4-hydroxy-,C7-9-branched alkyl esters has been extensively tested towards various organisms. The following table reflects the outcome of these tests:

Test organism	Test duration	Effect parameter	Effect value mg/kg soil/sed d.w	Nominal/ measured	OECD guideline	Vehicle	Remarks
Eisenia fetida	14d	NOEC	>=1000	nominal	207	yes	No effects at the highest test concentrations
Eisenia fetida	56d	NOEC	=250	nominal	222	yes
Brassica rapa Vicia sativa Lolium perenne	19d	NOEC	>=100	nominal	208	yes	No effects at the highest test concentration
Soil microorganisms	28d	NOEC (EC50)	31.6 (497)	nominal	217	yes	C-transformation
Soil microorganisms	28d	EC50	>1000	measured	216	yes	N-transformation

There are no data on the chronic toxicity of birds available. However, the substance has no toxicological classification that is relevant for secondary poisoning (see chapter 2 Classification and Labelling). Hence, the substance is considered not to cause toxic effects if accumulated. Therefore, secondary poisoning is of no concern for this substance.

Supporting assessment of the impurity Metilox (CAS 6386-38-5)

The effects on seedling emergence and early growth of higher plants were assessed with the three species Lolium perenne, Brassica rapa and Vicia sativa in growth test in accordance to OECD guideline 208. The test was conducted with nominal concentrations of 1, 10 and 100 mg/kg. No toxic effects were observed in all three species neither emergence nor growth.