Registration Dossier
Registration Dossier
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EC number: 204-648-7 | CAS number: 123-75-1
Repeated dose toxicity: oral
Administrative data
- Endpoint:
- repeated dose toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 1974
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Russian publication.
Data source
Reference
- Title:
- p 29 - 32
- Author:
- Zaeva, G
- Year:
- 1 974
- Bibliographic source:
- Gig. Tr. Prof. Zabol. 2
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Pyrrolidine
- EC Number:
- 204-648-7
- EC Name:
- Pyrrolidine
- Cas Number:
- 123-75-1
- Molecular formula:
- C4H9N
- IUPAC Name:
- pyrrolidine
- Details on test material:
- Test substance: 10 % aqueous solution
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- female
Administration / exposure
- Route of administration:
- oral: gavage
- Duration of treatment / exposure:
- 6 times
- Frequency of treatment:
- no data
Doses / concentrations
- Remarks:
- Doses / Concentrations:
200 - 500 mg/kg
Basis:
- Control animals:
- not specified
Results and discussion
Effect levels
- Basis for effect level:
- other: At 300 mg/kg 50 % of the rats died; no further results available.
- Remarks on result:
- not measured/tested
- Remarks:
- Effect level not specified (migrated information)
Target system / organ toxicity
- Critical effects observed:
- not specified
Any other information on results incl. tables
At 300 mg/kg 50 % of the rats died.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
