Registration Dossier
Registration Dossier
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EC number: 204-648-7 | CAS number: 123-75-1
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
The toxicity of Pyrrolidine to aquatic algae was assessed according to
OECD guideline No. 201 and GLP principles. Nominal exposure
concentrations were the following:
Range-finding test: 0.1, 1.0, 10 and 100 mg/L;
Final test: 1.0, 3.2, 10, 32 and 100 mg/L
The EC50 for growth rate reduction (ERC50: 0 -72h) was 39 mg/L and the
EC10 (ERC10: 0 -72h) was 10 mg/L. The EC50 for yield inhibition (EYC50:
0-72h) was 16 mg/L and the EC10 for yield inhibition (EYC10: 0-72h) was
4.2 mg/L. All criteria for acceptability of the test were met according
to OECD guideline No. 201 and the test is categorized as reliable
without restrictions.
The toxicity of Pyrrolidine to marine algae (Skeletonema costatum) was
assessed according to ISO 1025. The ErC50 resultet in 3.1 mg/L after 72h.
The test was categorized as reliable with restrictions.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 39 mg/L
- EC50 for marine water algae:
- 3.1 mg/L
- EC10 or NOEC for freshwater algae:
- 10 mg/L
Additional information
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