Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 270-109-8 | CAS number: 68411-20-1
Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
Description of key information
Performing of a BCF study with this complex substance is considerd to be technically not feasible. However a QSAR for the final product of the hydrolys and especially the hydrolysis in the presence of light, 3-ethyl-4-propyl-quinoline yielded an estimated BCF of 596 L/kg wwt (logBCF= 2.77). This result indicates that the final product of butanal reaction products with aniline in water does not meet the B criterion.
Key value for chemical safety assessment
Additional information
It has been demonstated in the waiving statements that the substance is not only complex and contains a high number of components, but it is also not stable in water and has a complex reaction pattern in water.
A search in the ECHA database and other public databases as well as in REACH guidance documents did not lead to examples or guidances for BCF studies performed with UVCB substances. The Registrant is aware that this item is currently under discussion in expert groups, e.g. from CEFIC and ECHA. As a BCF study is consuming animals, the Registrant is willing performing of a such study (after having stated a study proposal) if an adequate and scientifically found study design is available which allows the proper determination of a BCF value.
Having the B criterion in focus, a more detailed analysis of the hydrolysis products will be performed which also allows to fully compare the analysis of the UVCB substance "butanal, reaction products with aniline" (via GC-MS) with the analytical method performed on the hydrolysis products (LC-MS). After further analytical characterization of relevant compounds the corresponding BCFs will be estimated via QSAR with an accepted calculation method and correlated with the abiotic and/or biotic degradation properties of the respective compound.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
