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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
toxicity to terrestrial plants: short-term
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Acceptable, well documented publication which meets basic scientific principles.

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
No information
Author:
Feng L, Wang L, Zhao Y, Bong S (1996). Effects of substituted anilines and phenols on root elongation of cabbage seed. Chemosphere 32 (8), 1575-1584.
Reference Type:
secondary source
Title:
p-Toluidine - CAS No: 106-49-0 - SIDS Initial Assessment Report.
Author:
OECD
Year:
2005
Bibliographic source:
UNEP Publications

Materials and methods

Principles of method if other than guideline:
Effects of p-Toluidine on root elongation of cabbage (Chinese) seed were observed, and the acute toxicity towards root elongations (EC50 mg/l) was determined. Test was conducted for 120 h under semi-static conditions in Petri Dishes.
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
p-toluidine
EC Number:
203-403-1
EC Name:
p-toluidine
Cas Number:
106-49-0
Molecular formula:
C7H9N
IUPAC Name:
4-methylaniline
Details on test material:
- Name of test material (as cited in study report): 4-toluidine
- Analytical purity: = 95%

Test organisms

Species:
Brassica campestris var. chinensis

Study design

Test type:
other: root elongation toxicity test
Study type:
laboratory study
Substrate type:
filter paper
Limit test:
no
Total exposure duration:
120 h

Test conditions

Test temperature:
25 ± 1°C
pH:
6.58 - 7.12
Nominal and measured concentrations:
- 6 concentrations tested in geometric series in a ratio of 1.5 - 2.0

Results and discussion

Effect concentrations
Species:
Brassica campestris var. chinensis
Duration:
120 h
Dose descriptor:
EC50
Effect conc.:
102.2 other: mg/l
Nominal / measured:
nominal
Basis for effect:
growth

Applicant's summary and conclusion