Registration Dossier
Registration Dossier
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EC number: 203-403-1 | CAS number: 106-49-0
Partition coefficient
Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Data from handbook or collection of data Adopted according to HSDB (Peer reviewed data base)
Data source
Referenceopen allclose all
- Reference Type:
- review article or handbook
- Title:
- Exploring QSAR. Hydrophobic, Electronic, and Steric Constants.
- Author:
- Hansch C, Leo A and Hoekmann D
- Year:
- 1 995
- Bibliographic source:
- ACS Professional Refernce Book. Amaerican Chemical Society, Washington, DC, p. 32
- Reference Type:
- review article or handbook
- Title:
- 4-Aminotoluene
- Author:
- HSDB
- Year:
- 2 009
- Bibliographic source:
- National Library of Medicine (NLM)
Materials and methods
- Principles of method if other than guideline:
- secondary peer reviewed source, valid collection of data
- GLP compliance:
- not specified
- Partition coefficient type:
- octanol-water
Test material
- Reference substance name:
- p-toluidine
- EC Number:
- 203-403-1
- EC Name:
- p-toluidine
- Cas Number:
- 106-49-0
- Molecular formula:
- C7H9N
- IUPAC Name:
- 4-methylaniline
- Details on test material:
- - Name of test material (as cited in study report): p-Toluidine
- Analytical purity: not specified
Constituent 1
Results and discussion
Partition coefficientopen allclose all
- Type:
- log Pow
- Partition coefficient:
- 1.44
- pH:
- 7.4
- Type:
- log Pow
- Partition coefficient:
- 1.39
- Type:
- log Pow
- Partition coefficient:
- 1.39
- pH:
- 7.5
Any other information on results incl. tables
Temperature was not specified. Three values were given: 1.39, 1.39, and 1.44 from 3 different sources. log Pow 1.44 was signed as preferred value. log Pow 1.39 was signed as preferred value for the neutral form (this value is cited in HSDB).
Applicant's summary and conclusion
- Executive summary:
Hansch C, 1995
The measured logPow of p-toluidine is 1.39.
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