Registration Dossier
Registration Dossier
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EC number: 700-102-1 | CAS number: 105112-76-3
Toxicological Summary
Administrative data
Workers - Hazard via inhalation route
Systemic effects
Acute/short term exposure
DNEL related information
Local effects
Acute/short term exposure
DNEL related information
Workers - Hazard via dermal route
Systemic effects
Acute/short term exposure
DNEL related information
Workers - Hazard for the eyes
Additional information - workers
The substance 3,3'-[biphenyl-4,4'-diylbis(oxy)]dianiline is not imported or used as such in the European Union. It is contained as an unintended residual monomer in the polyimide resins imported into the EU in form of powder, pellets or compounds, which are used in the manufacture by heat moulding of articles for industrial use such as in the automotive industry. However, the concentration of 3,3'-[biphenyl-4,4'-diylbis(oxy)]dianiline in the resins is negligible (< 0.1 ppm). A release of substance from the resins is highly unlikely because of the low vapour pressure, low water solubility and moderate octanol-water partition coefficient of 3,3'-[biphenyl-4,4'-diylbis(oxy)]dianiline. During the heat moulding process, any residual 3,3'-[biphenyl-4,4'-diylbis(oxy)]dianiline will decompose thermally. Therefore, no human exposure to 3,3'-[biphenyl-4,4'-diylbis(oxy)]dianiline is expected for the identified use of the substance in the EU. No exposure and risk assessments are performed because of the negligible human exposure, and DNELs are not derived.
General Population - Hazard via inhalation route
Systemic effects
Acute/short term exposure
DNEL related information
Local effects
Acute/short term exposure
DNEL related information
General Population - Hazard via dermal route
Systemic effects
Acute/short term exposure
DNEL related information
General Population - Hazard via oral route
Systemic effects
Acute/short term exposure
DNEL related information
General Population - Hazard for the eyes
Additional information - General Population
Exposure of the general public to 3,3'-[biphenyl-4,4'-diylbis(oxy)]dianiline from its use in the European Union is highly unlikely and considered as negligible. Thus, no DNELs for the general public have been derived.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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