Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Direct observations: clinical cases, poisoning incidents and other

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Administrative data

Endpoint:
direct observations: clinical cases, poisoning incidents and other
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment

Data source

Reference
Reference Type:
publication
Title:
Piperidine—A hazardous chemical
Author:
Linch AL
Year:
1965
Bibliographic source:
Am. Ind. Hyg. Assoc. J. 26:95-96

Materials and methods

Study type:
poisoning incident
Endpoint addressed:
skin irritation / corrosion
Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
A worker was sprayed with piperidine when transferring the chemical under room temperature conditions. Contact time with the chemical was less than 3 min.
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Piperidine
EC Number:
203-813-0
EC Name:
Piperidine
Cas Number:
110-89-4
Molecular formula:
C5H11N
IUPAC Name:
piperidine

Method

Subjects:
- Number of subjects exposed: 1
- Sex: male
Route of exposure:
dermal
Reason of exposure:
accidental
Exposure assessment:
not specified

Results and discussion

Clinical signs:
The worker suffered first degree burns on the face, left ear, and neck; second degree burns on the forearms and abdomen, and third-degree burns on the chest.

Applicant's summary and conclusion