Registration Dossier
Registration Dossier
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EC number: 203-219-1 | CAS number: 104-61-0
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
EU Method C.2, GLP, key study, validity 2:
48h-EC50 = 59.6 mg/L.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 59.6 mg/L
Additional information
One valid key study is available to assess the 48h acute toxicity of γ-nonalactone to aquatic invertebrates. Daphnia magna were exposed to the test substance at nominal concentrations of 0 (blank control), 25, 50 and 100 mg/L under static conditions. An analytical monitoring of the concentrations was performed at t=0h and t=48h. The concentrations were maintained during the exposure period (98 to 106.4% of the initial concentrations after 48 hours), therefore the result was based on nominal values. The 48h-EC50 was determined by geometric mean of EC0 and EC100 values and corresponds to 52 mg/L. However, this value was recalculated with ToxRat Professional software v2.10 and corresponds to 59.6 mg/L.
The 48h-EC50 at 59.6 mg/L was chosen for the chemical safety assessment.
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